Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function
Kumar, Manish, Molkentine, David, Molkentine, Jessica, Bridges, Kathleen, Xie, Tongxin, Yang, Liangpeng, Hefner, Andrew, Gao, Meng, Bahri, Reshub, Dhawan, Annika, Frederick, Mitchell J., Seth, Sahil, Abdelhakiem, Mohamed, Beadle, Beth M., Johnson, Faye, Wang, Jing, Shen, Li, Heffernan, Timothy, Sheth, Aakash, Ferris, Robert L., Myers, Jeffrey N., Pickering, Curtis R., Skinner, Heath D.
Published in Nature communications (03.11.2021)
Published in Nature communications (03.11.2021)
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BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer
Liu, Xiyou, Kumar, Manish, Yang, Liangpeng, Molkentine, David P, Valdecanas, David, Yu, Shiying, Meyn, Raymond E, Heymach, John V, Skinner, Heath D
Published in Clinical cancer research (01.02.2018)
Published in Clinical cancer research (01.02.2018)
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p16 Represses DNA Damage Repair via a Novel Ubiquitin-Dependent Signaling Cascade
Molkentine, David P, Molkentine, Jessica M, Bridges, Kathleen A, Valdecanas, David R, Dhawan, Annika, Bahri, Reshub, Hefner, Andrew J, Kumar, Manish, Yang, Liangpeng, Abdelhakiem, Mohamed, Pifer, Phillip M, Sandulache, Vlad, Sheth, Aakash, Beadle, Beth M, Thames, Howard D, Mason, Kathryn A, Pickering, Curtis R, Meyn, Raymond E, Skinner, Heath D
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Published in Cancer research (Chicago, Ill.) (01.03.2022)
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Combination treatment with radiotherapy and a novel oxidative phosphorylation inhibitor overcomes PD-1 resistance and enhances antitumor immunity
Chen, Dawei, Barsoumian, Hampartsoum B, Fischer, Grant, Yang, Liangpeng, Verma, Vivek, Younes, Ahmed I, Hu, Yun, Masropour, Fatemeh, Klein, Katherine, Vellano, Christopher, Marszalek, Joseph, Davies, Michael, Cortez, Maria Angelica, Welsh, James
Published in Journal for immunotherapy of cancer (01.06.2020)
Published in Journal for immunotherapy of cancer (01.06.2020)
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A radioenhancing nanoparticle mediated immunoradiation improves survival and generates long-term antitumor immune memory in an anti-PD1-resistant murine lung cancer model
Hu, Yun, Paris, Sébastien, Barsoumian, Hampartsoum, Abana, Chike O, He, Kewen, Sezen, Duygu, Wasley, Mark, Masrorpour, Fatemeh, Chen, Dawei, Yang, Liangpeng, Dunn, Joe D, Gandhi, Saumil, Nguyen, Quynh-Nhu, Cortez, Maria Angelica, Welsh, James W
Published in Journal of nanobiotechnology (11.12.2021)
Published in Journal of nanobiotechnology (11.12.2021)
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Combining a nanoparticle-mediated immunoradiotherapy with dual blockade of LAG3 and TIGIT improves the treatment efficacy in anti-PD1 resistant lung cancer
Hu, Yun, Paris, Sébastien, Bertolet, Genevieve, Barsoumian, Hampartsoum B, He, Kewen, Sezen, Duygu, Chen, Dawei, Wasley, Mark, SILVA, Jordan DA, Mitchell, Joylise A, Voss, Tiffany A, Masrorpour, Fatemeh, Leyton, Claudia Kettlun, Yang, Liangpeng, Leuschner, Carola, Puebla-Osorio, Nahum, Gandhi, Saumil, Nguyen, Quynh-Nhu, Cortez, Maria Angelica, Welsh, James W
Published in Journal of nanobiotechnology (19.09.2022)
Published in Journal of nanobiotechnology (19.09.2022)
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Addition of TLR9 agonist immunotherapy to radiation improves systemic antitumor activity
Younes, Ahmed I., Barsoumian, Hampartsoum B., Sezen, Duygu, Verma, Vivek, Patel, Roshal, Wasley, Mark, Hu, Yun, Dunn, Joe D., He, Kewen, Chen, Dawei, Menon, Hari, Masrorpour, Fatemeh, Gu, Meidi, Yang, Liangpeng, Puebla-Osorio, Nahum, Cortez, Maria Angelica, Welsh, James W.
Published in Translational oncology (01.02.2021)
Published in Translational oncology (01.02.2021)
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Polymyxin B, in combination with fluconazole, exerts a potent fungicidal effect
Zhai, Bing, Zhou, Henry, Yang, Liangpeng, Zhang, Jun, Jung, Kathy, Giam, Chou-Zen, Xiang, Xin, Lin, Xiaorong
Published in Journal of antimicrobial chemotherapy (01.05.2010)
Published in Journal of antimicrobial chemotherapy (01.05.2010)
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Complex Cell Cycle Abnormalities Caused by Human T-Lymphotropic Virus Type 1 Tax
Yang, Liangpeng, Kotomura, Naoe, Ho, Yik-Khuan, Zhi, Huijun, Bixler, Sandra, Schell, Michael J, Giam, Chou-Zen
Published in Journal of Virology (01.03.2011)
Published in Journal of Virology (01.03.2011)
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575 Dual blockade of LAG3 and TIGIT improves the treatment efficacy of a nanoparticle-mediated immunoradiation in anti-PD1 resistant lung cancer in mice
Hu, Yun, Welsh, James, Paris, Sebastien, Bertolet, Genevieve, Barsoumian, Hampartsoum, Schuda, Lily, He, Kewen, Sezen, Duygu, Wasley, Mark, Mitchell, Joylise, Voss, Tiffany, Masrorpour, Fatemeh, Jordan, SILVA, Leyton, Claudia Kettlun, Yang, Liangpeng, Puebla-Osorio, Nahum, Gandhi, Saumil, Nguyen, Quynh-Nhu, Cortez, Angelica
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Human T-Cell Leukemia Virus Type 1 Infection Leads to Arrest in the G1 Phase of the Cell Cycle
Liu, Meihong, Yang, Liangpeng, Zhang, Ling, Liu, Baoying, Merling, Randall, Xia, Zheng, Giam, Chou-Zen
Published in Journal of Virology (01.09.2008)
Published in Journal of Virology (01.09.2008)
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Radiation Therapy Enhanced by NBTXR3 Nanoparticles Overcomes Anti-PD1 Resistance and Evokes Abscopal Effects
Hu, Yun, Paris, Sébastien, Barsoumian, Hampartsoum, Abana, Chike O., He, Kewen, Wasley, Mark, Younes, Ahmed I., Masrorpour, Fatemeh, Chen, Dawei, Yang, Liangpeng, Dunn, Joe Dan, Zhang, Jie, Gandhi, Saumil, Nguyen, Quynh-Nhu, Cortez, Maria Angelica, Welsh, James
Published in International journal of radiation oncology, biology, physics (01.11.2021)
Published in International journal of radiation oncology, biology, physics (01.11.2021)
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FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner
Pifer, Phillip M, Yang, Liangpeng, Kumar, Manish, Xie, Tongxin, Frederick, Mitchell, Hefner, Andrew, Beadle, Beth, Molkentine, David, Molkentine, Jessica, Dhawan, Annika, Abdelhakiem, Mohamed, Osman, Abdullah A, Leibowitz, Brian J, Myers, Jeffrey N, Pickering, Curtis R, Sandulache, Vlad C, Heymach, John, Skinner, Heath D
Published in Clinical cancer research (05.01.2024)
Published in Clinical cancer research (05.01.2024)
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SHP-2 and PD-L1 Inhibition Combined with Radiotherapy Enhances Systemic Antitumor Effects in an Anti-PD-1-Resistant Model of Non-Small Cell Lung Cancer
Chen, Dawei, Barsoumian, Hampartsoum B, Yang, Liangpeng, Younes, Ahmed I, Verma, Vivek, Hu, Yun, Menon, Hari, Wasley, Mark, Masropour, Fatemeh, Mosaffa, Sara, Ozgen, Tugce, Klein, Katherine, Cortez, Maria Angelica, Welsh, James W
Published in Cancer immunology research (01.07.2020)
Published in Cancer immunology research (01.07.2020)
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Abstract 6185: In vivo screening in HPV positive and HPV negative head and neck squamous cell carcinoma
Abdelhakiem, Mohamed K., Yang, Liangpeng, Xie, Tongxin, Kumar, Manish, Molkentine, David, Sheth, Aakash, Frederick, Mitchell, Myers, Jeffrey, Pickering, Curtis R., Skinner, Heath D.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Targeting DNA damage response in head and neck cancers through abrogation of cell cycle checkpoints
Molkentine, Jessica M., Molkentine, David P., Bridges, Kathleen A., Xie, Tongxin, Yang, Liangpeng, Sheth, Aakash, Heffernan, Timothy P., Clump, David A., Faust, Alma Z., Ferris, Robert L., Myers, Jeffrey N., Frederick, Mitchell J., Mason, Kathryn A., Meyn, Raymond E., Pickering, Curtis R., Skinner, Heath D.
Published in International journal of radiation biology (03.08.2021)
Published in International journal of radiation biology (03.08.2021)
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High Plus Low Dose Radiation Strategy in Combination with TIGIT and PD1 Blockade to Promote Systemic Antitumor Responses
Barsoumian, Hampartsoum B, Sezen, Duygu, Menon, Hari, Younes, Ahmed I, Hu, Yun, He, Kewen, Puebla-Osorio, Nahum, Wasley, Mark, Hsu, Ethan, Patel, Roshal R, Yang, Liangpeng, Cortez, Maria A, Welsh, James W
Published in Cancers (03.01.2022)
Published in Cancers (03.01.2022)
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Abstract 978: In vivo shRNA screening identifies synthetic cytotoxicity in CREBBP/EP300 mutant head and neck cancer
Kumar, Manish, Bridges, Kathleen, Molkentine, David, Yang, Liangpeng, Sheth, Aakash, Meyn, Raymond, Frederick, Mitchell, Myers, Jeffrey, Pickering, Curtis, Skinner, Heath D.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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(OA30) In Vivo Screening Identifies ESR1 as a Clinically Relevant Target for Radiosensitization In HNSCC
Sheth, Aakash, Molkentine, David, Bridges, Second Author, Kathleen, Kumar, Yang, Liangpeng, Xie, Tongxin, Fredrick, Mitchell, Myers, Jeffrey, Meyn, Raymond, Pickering, Curtis, Skinner, Heath
Published in International journal of radiation oncology, biology, physics (01.06.2018)
Published in International journal of radiation oncology, biology, physics (01.06.2018)
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