Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease
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Published in The New England journal of medicine (25.12.2008)
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Published in Diabetes (New York, N.Y.) (01.10.2007)
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Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes
Liu, Yuk-Fun, Powrie, Jake, Arif, Sefina, Yang, Jennie H M, Williams, Evangelia, Khatri, Leena, Joshi, Mamta, Lhuillier, Loic, Fountoulakis, Nikolaos, Smith, Emma, Beam, Craig, Lorenc, Anna, Peakman, Mark, Tree, Timothy
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Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource
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Published in Nature genetics (01.09.2009)
Published in Nature genetics (01.09.2009)
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miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment
Lopez, Juan Pablo, Lim, Raymond, Cruceanu, Cristiana, Crapper, Liam, Fasano, Caroline, Labonte, Benoit, Maussion, Gilles, Yang, Jennie P, Yerko, Volodymyr, Vigneault, Erika, El Mestikawy, Salah, Mechawar, Naguib, Pavlidis, Paul, Turecki, Gustavo
Published in Nature medicine (01.07.2014)
Published in Nature medicine (01.07.2014)
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Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes
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Published in Human molecular genetics (15.06.2012)
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IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors
Whitehouse, Gavin, Gray, Elizabeth, Mastoridis, Sotiris, Merritt, Elliot, Kodela, Elisavet, Yang, Jennie H. M., Danger, Richard, Mairal, Marta, Christakoudi, Sofia, Lozano, Juan J., Macdougall, Iain C., Tree, Timothy I. M., Sanchez-Fueyo, Alberto, Martinez-Llordella, Marc
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2017)
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Type 1 diabetes-associated IL2RA variation lowers IL-2 signaling and contributes to diminished CD4+CD25+ regulatory T cell function
Garg, Garima, Tyler, Jennifer R, Yang, Jennie H M, Cutler, Antony J, Downes, Kate, Pekalski, Marcin, Bell, Gwynneth L, Nutland, Sarah, Peakman, Mark, Todd, John A, Wicker, Linda S, Tree, Timothy I M
Published in The Journal of immunology (1950) (01.05.2012)
Published in The Journal of immunology (1950) (01.05.2012)
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Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing
Heap, Graham A., Yang, Jennie H.M., Downes, Kate, Healy, Barry C., Hunt, Karen A., Bockett, Nicholas, Franke, Lude, Dubois, Patrick C., Mein, Charles A., Dobson, Richard J., Albert, Thomas J., Rodesch, Matthew J., Clayton, David G., Todd, John A., van Heel, David A., Plagnol, Vincent
Published in Human molecular genetics (01.01.2010)
Published in Human molecular genetics (01.01.2010)
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Low-dose IL-2 reduces IL-21+ T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes
Zhang, Jia-Yuan, Hamey, Fiona, Trzupek, Dominik, Mickunas, Marius, Lee, Mercede, Godfrey, Leila, Yang, Jennie H. M., Pekalski, Marcin L., Kennet, Jane, Waldron-Lynch, Frank, Evans, Mark L., Tree, Timothy I. M., Wicker, Linda S., Todd, John A., Ferreira, Ricardo C.
Published in Nature communications (28.11.2022)
Published in Nature communications (28.11.2022)
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Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes
Yang, Jennie H M, Cutler, Antony J, Ferreira, Ricardo C, Reading, James L, Cooper, Nicholas J, Wallace, Chris, Clarke, Pamela, Smyth, Deborah J, Boyce, Christopher S, Gao, Guo-Jian, Todd, John A, Wicker, Linda S, Tree, Timothy I M
Published in Diabetes (New York, N.Y.) (01.11.2015)
Published in Diabetes (New York, N.Y.) (01.11.2015)
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Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes
Alhadj Ali, Mohammad, Liu, Yuk-Fun, Arif, Sefina, Tatovic, Danijela, Shariff, Hina, Gibson, Vivienne B, Yusuf, Norkhairin, Baptista, Roman, Eichmann, Martin, Petrov, Nedyalko, Heck, Susanne, Yang, Jennie H M, Tree, Timothy I M, Pujol-Autonell, Irma, Yeo, Lorraine, Baumard, Lucas, Stenson, Rachel, Howell, Alex, Clark, Alison, Boult, Zoe, Powrie, Jake, Adams, Laura, Wong, Florence S, Luzio, Stephen, Dunseath, Gareth, Green, Kate, O'Keefe, Alison, Bayly, Graham, Thorogood, Natasha, Andrews, Robert, Leech, Nicola, Joseph, Frank, Nair, Sunil, Seal, Susan, Cheung, HoYee, Beam, Craig, Hills, Robert, Peakman, Mark, Dayan, Colin M
Published in Science translational medicine (09.08.2017)
Published in Science translational medicine (09.08.2017)
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Clinical-grade multipotent adult progenitor cells durably control pathogenic T cell responses in human models of transplantation and autoimmunity
Reading, James L, Yang, Jennie H M, Sabbah, Shereen, Skowera, Ania, Knight, Robin R, Pinxteren, Jef, Vaes, Bart, Allsopp, Timothy, Ting, Anthony E, Busch, Sarah, Raber, Amy, Deans, Robert, Tree, Timothy I M
Published in The Journal of immunology (1950) (01.05.2013)
Published in The Journal of immunology (1950) (01.05.2013)
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Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes
Maitra, Malosree, Mitsuhashi, Haruka, Rahimian, Reza, Chawla, Anjali, Yang, Jennie, Fiori, Laura M., Davoli, Maria Antonietta, Perlman, Kelly, Aouabed, Zahia, Mash, Deborah C., Suderman, Matthew, Mechawar, Naguib, Turecki, Gustavo, Nagy, Corina
Published in Nature communications (22.05.2023)
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Ustekinumab for type 1 diabetes in adolescents: a multicenter, double-blind, randomized phase 2 trial
Tatovic, Danijela, Marwaha, Ashish, Taylor, Peter, Hanna, Stephanie J., Carter, Kym, Cheung, W. Y., Luzio, Steve, Dunseath, Gareth, Hutchings, Hayley A., Holland, Gail, Hiles, Steve, Fegan, Greg, Williams, Evangelia, Yang, Jennie H. M., Domingo-Vila, Clara, Pollock, Emily, Wadud, Muntaha, Ward-Hartstonge, Kirsten, Marques-Jones, Susie, Bowen-Morris, Jane, Stenson, Rachel, Levings, Megan K., Gregory, John W., Tree, Timothy I. M., Dayan, Colin
Published in Nature medicine (01.09.2024)
Published in Nature medicine (01.09.2024)
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Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
Todd, John A, Walker, Neil M, Cooper, Jason D, Smyth, Deborah J, Downes, Kate, Plagnol, Vincent, Bailey, Rebecca, Nejentsev, Sergey, Field, Sarah F, Payne, Felicity, Lowe, Christopher E, Szeszko, Jeffrey S, Hafler, Jason P, Zeitels, Lauren, Yang, Jennie H M, Vella, Adrian, Nutland, Sarah, Stevens, Helen E, Schuilenburg, Helen, Coleman, Gillian, Maisuria, Meeta, Meadows, William, Smink, Luc J, Healy, Barry, Burren, Oliver S, Lam, Alex A C, Ovington, Nigel R, Allen, James, Adlem, Ellen, Leung, Hin-Tak, Wallace, Chris, Howson, Joanna M M, Guja, Cristian, Ionescu-Tîrgovi te, Constantin, Simmonds, Matthew J, Heward, Joanne M, Gough, Stephen C L, Dunger, David B, Wicker, Linda S, Clayton, David G
Published in Nature genetics (01.07.2007)
Published in Nature genetics (01.07.2007)
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Guidelines for standardizing T‐cell cytometry assays to link biomarkers, mechanisms, and disease outcomes in type 1 diabetes
Yang, Jennie H. M., Ward‐Hartstonge, Kirsten A., Perry, Daniel J., Blanchfield, J. Lori, Posgai, Amanda L., Wiedeman, Alice E., Diggins, Kirsten, Rahman, Adeeb, Tree, Timothy I. M., Brusko, Todd M., Levings, Megan K., James, Eddie A., Kent, Sally C., Speake, Cate, Homann, Dirk, Long, S. Alice
Published in European journal of immunology (01.03.2022)
Published in European journal of immunology (01.03.2022)
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Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial
Todd, John A, Evangelou, Marina, Cutler, Antony J, Pekalski, Marcin L, Walker, Neil M, Stevens, Helen E, Porter, Linsey, Smyth, Deborah J, Rainbow, Daniel B, Ferreira, Ricardo C, Esposito, Laura, Hunter, Kara M D, Loudon, Kevin, Irons, Kathryn, Yang, Jennie H, Bell, Charles J M, Schuilenburg, Helen, Heywood, James, Challis, Ben, Neupane, Sankalpa, Clarke, Pamela, Coleman, Gillian, Dawson, Sarah, Goymer, Donna, Anselmiova, Katerina, Kennet, Jane, Brown, Judy, Caddy, Sarah L, Lu, Jia, Greatorex, Jane, Goodfellow, Ian, Wallace, Chris, Tree, Tim I, Evans, Mark, Mander, Adrian P, Bond, Simon, Wicker, Linda S, Waldron-Lynch, Frank
Published in PLoS medicine (11.10.2016)
Published in PLoS medicine (11.10.2016)
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Dysfunction of Astrocyte Connexins 30 and 43 in Dorsal Lateral Prefrontal Cortex of Suicide Completers
Ernst, Carl, Nagy, Corina, Kim, Sangyheon, Yang, Jennie P, Deng, Xiaoming, Hellstrom, Ian C, Choi, Kwang Ho, Gershenfeld, Howard, Meaney, Michael J, Turecki, Gustavo
Published in Biological psychiatry (1969) (15.08.2011)
Published in Biological psychiatry (1969) (15.08.2011)
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Single-cell RNAseq identifies clonally expanded antigen-specific T-cells following intradermal injection of gold nanoparticles loaded with diabetes autoantigen in humans
Hanna, Stephanie J, Thayer, Terri C, Robinson, Emma J S, Vinh, Ngoc-Nga, Williams, Nigel, Landry, Laurie G, Andrews, Robert, Siah, Qi Zhuang, Leete, Pia, Wyatt, Rebecca, McAteer, Martina A, Nakayama, Maki, Wong, F Susan, Yang, Jennie H M, Tree, Timothy I M, Ludvigsson, Johnny, Dayan, Colin M, Tatovic, Danijela
Published in Frontiers in immunology (2023)
Published in Frontiers in immunology (2023)
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