The Knockout Mouse Project
Austin, Christopher P, Battey, James F, Bradley, Allan, Bucan, Maja, Capecchi, Mario, Collins, Francis S, Dove, William F, Duyk, Geoffrey, Dymecki, Susan, Eppig, Janan T, Grieder, Franziska B, Heintz, Nathaniel, Hicks, Geoff, Insel, Thomas R, Joyner, Alexandra, Koller, Beverly H, Lloyd, K C Kent, Magnuson, Terry, Moore, Mark W, Nagy, Andras, Pollock, Jonathan D, Roses, Allen D, Sands, Arthur T, Seed, Brian, Skarnes, William C, Snoddy, Jay, Soriano, Philippe, Stewart, David J, Stewart, Francis, Stillman, Bruce, Varmus, Harold, Varticovski, Lyuba, Verma, Inder M, Vogt, Thomas F, von Melchner, Harald, Witkowski, Jan, Woychik, Richard P, Wurst, Wolfgang, Yancopoulos, George D, Young, Stephen G, Zambrowicz, Brian
Published in Nature genetics (01.09.2004)
Published in Nature genetics (01.09.2004)
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Neurotrophin-3: A Neurotrophic Factor Related to NGF and BDNF
Maisonpierre, Peter C., Belluscio, Leonardo, Squinto, Stephen, Ip, Nancy Y., Furth, Mark E., Lindsay, Ronald M., Yancopoulos, George D.
Published in Science (American Association for the Advancement of Science) (23.03.1990)
Published in Science (American Association for the Advancement of Science) (23.03.1990)
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Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials
Bachert, Claus, Han, Joseph K, Desrosiers, Martin, Hellings, Peter W, Amin, Nikhil, Lee, Stella E, Mullol, Joaquim, Greos, Leon S, Bosso, John V, Laidlaw, Tanya M, Cervin, Anders U, Maspero, Jorge F, Hopkins, Claire, Olze, Heidi, Canonica, G Walter, Paggiaro, Pierluigi, Cho, Seong H, Fokkens, Wytske J, Fujieda, Shigeharu, Zhang, Mei, Lu, Xin, Fan, Chunpeng, Draikiwicz, Steven, Kamat, Siddhesh A, Khan, Asif, Pirozzi, Gianluca, Patel, Naimish, Graham, Neil M H, Ruddy, Marcella, Staudinger, Heribert, Weinreich, David, Stahl, Neil, Yancopoulos, George D, Mannent, Leda P
Published in The Lancet (British edition) (02.11.2019)
Published in The Lancet (British edition) (02.11.2019)
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Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial
Bachert, Claus, Mannent, Leda, Naclerio, Robert M, Mullol, Joaquim, Ferguson, Berrylin J, Gevaert, Philippe, Hellings, Peter, Jiao, Lixia, Wang, Lin, Evans, Robert R, Pirozzi, Gianluca, Graham, Neil M, Swanson, Brian, Hamilton, Jennifer D, Radin, Allen, Gandhi, Namita A, Stahl, Neil, Yancopoulos, George D, Sutherland, E. Rand
Published in JAMA : the journal of the American Medical Association (02.02.2016)
Published in JAMA : the journal of the American Medical Association (02.02.2016)
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Soluble Forms of the Interleukin-6 Signal-Transducing Receptor Component gp130 in Human Serum Possessing a Potential to Inhibit Signals Through Membrane-Anchored gp130
Narazaki, Masashi, Yasukawa, Kiyoshi, Saito, Takashi, Ohsugi, Yoshiyuki, Fukui, Hiroyasu, Koishihara, Yasuo, Yancopoulos, George D., Taga, Tetsuya, Kishimoto, Tadamitsu
Published in Blood (15.08.1993)
Published in Blood (15.08.1993)
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Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6
Mostoslavsky, Raul, Chua, Katrin F., Lombard, David B., Pang, Wendy W., Fischer, Miriam R., Gellon, Lionel, Liu, Pingfang, Mostoslavsky, Gustavo, Franco, Sonia, Murphy, Michael M., Mills, Kevin D., Patel, Parin, Hsu, Joyce T., Hong, Andrew L., Ford, Ethan, Cheng, Hwei-Ling, Kennedy, Caitlin, Nunez, Nomeli, Bronson, Roderick, Frendewey, David, Auerbach, Wojtek, Valenzuela, David, Karow, Margaret, Hottiger, Michael O., Hursting, Stephen, Barrett, J. Carl, Guarente, Leonard, Mulligan, Richard, Demple, Bruce, Yancopoulos, George D., Alt, Frederick W.
Published in Cell (27.01.2006)
Published in Cell (27.01.2006)
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Inhibition of Vascular Endothelial Growth Factor (VEGF) Signaling in Cancer Causes Loss of Endothelial Fenestrations, Regression of Tumor Vessels, and Appearance of Basement Membrane Ghosts
Inai, Tetsuichiro, Mancuso, Michael, Hashizume, Hiroya, Baffert, Fabienne, Haskell, Amy, Baluk, Peter, Hu-Lowe, Dana D., Shalinsky, David R., Thurston, Gavin, Yancopoulos, George D., McDonald, Donald M.
Published in The American journal of pathology (01.07.2004)
Published in The American journal of pathology (01.07.2004)
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Lhx6 Delineates a Pathway Mediating Innate Reproductive Behaviors from the Amygdala to the Hypothalamus
Choi, Gloria B., Dong, Hong-wei, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Swanson, Larry W., Anderson, David J.
Published in Neuron (Cambridge, Mass.) (19.05.2005)
Published in Neuron (Cambridge, Mass.) (19.05.2005)
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Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways
Glass, David J, Rommel, Christian, Bodine, Sue C, Clarke, Brian A, Rossman, Roni, Nunez, Lorna, Stitt, Trevor N, Yancopoulos, George D
Published in Nature cell biology (01.11.2001)
Published in Nature cell biology (01.11.2001)
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Insulin-like Growth Factor-1 (IGF-1) Inversely Regulates Atrophy-induced Genes via the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Pathway
Latres, Esther, Amini, Ami R., Amini, Ashley A., Griffiths, Jennifer, Martin, Francis J., Wei, Yi, Lin, Hsin Chieh, Yancopoulos, George D., Glass, David J.
Published in The Journal of biological chemistry (28.01.2005)
Published in The Journal of biological chemistry (28.01.2005)
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Vascular-specific growth factors and blood vessel formation
Yancopoulos, George D, Davis, Samuel, Gale, Nicholas W, Rudge, John S, Wiegand, Stanley J, Holash, Jocelyn
Published in Nature (London) (14.09.2000)
Published in Nature (London) (14.09.2000)
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VEGF-Trap: A VEGF Blocker with Potent Antitumor Effects
Holash, Jocelyn, Davis, Sam, Papadopoulos, Nick, Croll, Susan D., Ho, Lillian, Russell, Michelle, Boland, Patricia, Leidich, Ray, Hylton, Donna, Burova, Elena, Ioffe, Ella, Huang, Tammy, Radziejewski, Czeslaw, Bailey, Kevin, Fandl, James P., Daly, Tom, Wiegand, Stanley J., Yancopoulos, George D., Rudge, John S.
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
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Conditional Activation of Akt in Adult Skeletal Muscle Induces Rapid Hypertrophy
Lai, Ka-Man V., Gonzalez, Michael, Poueymirou, William T., Kline, William O., Na, Erqian, Zlotchenko, Elizabeth, Stitt, Trevor N., Economides, Aris N., Yancopoulos, George D., Glass, David J.
Published in Molecular and Cellular Biology (01.11.2004)
Published in Molecular and Cellular Biology (01.11.2004)
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Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
Bodine, Sue C, Yancopoulos, George D, Stitt, Trevor N, Gonzalez, Michael, Kline, William O, Stover, Gretchen L, Bauerlein, Roy, Zlotchenko, Elizabeth, Scrimgeour, Angus, Lawrence, John C, Glass, David J
Published in Nature cell biology (01.11.2001)
Published in Nature cell biology (01.11.2001)
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Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis
Xia, Yu-Ping, Li, Baosheng, Hylton, Donna, Detmar, Michael, Yancopoulos, George D., Rudge, John S.
Published in Blood (01.07.2003)
Published in Blood (01.07.2003)
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Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy
Bodine, Sue C., Latres, Esther, Baumhueter, Susanne, Venus K.-M. Lai, Nunez, Lorna, Clarke, Brian A., Poueymirou, William T., Panaro, Frank J., Na, Erqian, Dharmarajan, Kumar, Pan, Zhen-Qiang, Valenzuela, David M., DeChiara, Thomas M., Stitt, Trevor N., Yancopoulos, George D., Glass, David J.
Published in Science (American Association for the Advancement of Science) (23.11.2001)
Published in Science (American Association for the Advancement of Science) (23.11.2001)
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Angiopoietin-2 Is Required for Postnatal Angiogenesis and Lymphatic Patterning, and Only the Latter Role Is Rescued by Angiopoietin-1
Gale, Nicholas W., Thurston, Gavin, Hackett, Sean F., Renard, Roumiana, Wang, Quan, McClain, Joyce, Martin, Cliff, Witte, Charles, Witte, Marlys H., Jackson, David, Suri, Chitra, Campochiaro, Peter A., Wiegand, Stanley J., Yancopoulos, George D.
Published in Developmental cell (01.09.2002)
Published in Developmental cell (01.09.2002)
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