Synthesis and Biological Evaluation of Quinuclidine Derivatives Incorporating Phenothiazine Moieties as Squalene Synthase Inhibitors
Ishihara, Tsukasa, Kakuta, Hirotoshi, Moritani, Hiroshi, Ugawa, Tohru, Yanagisawa, Isao
Published in Chemical & Pharmaceutical Bulletin (01.10.2004)
Published in Chemical & Pharmaceutical Bulletin (01.10.2004)
Get full text
Journal Article
Syntheses and biological evaluation of novel quinuclidine derivatives as squalene synthase inhibitors
Ishihara, Tsukasa, Kakuta, Hirotoshi, Moritani, Hiroshi, Ugawa, Tohru, Sakamoto, Shuichi, Tsukamoto, Shin-ichi, Yanagisawa, Isao
Published in Bioorganic & medicinal chemistry (29.05.2003)
Published in Bioorganic & medicinal chemistry (29.05.2003)
Get full text
Journal Article
The discovery of YM-60828: A potent, selective and orally-bioavailable factor Xa inhibitor
HIRAYAMA, Fukushi, KOSHIO, Hiroyuki, YANAGISAWA, Isao, KATAYAMA, Naoko, KURIHARA, Hiroyuki, TANIUCHI, Yuta, SATO, Kazuo, HISAMICHI, Nami, SAKAI-MORITANI, Yumiko, KAWASAKI, Tomihisa, MATSUMOTO, Yuzo
Published in Bioorganic & medicinal chemistry (01.05.2002)
Published in Bioorganic & medicinal chemistry (01.05.2002)
Get full text
Journal Article
An Easy Access to 7-Methyl-2-naphthalenecarbonitrile
Koshio, Hiroyuki, Ishihara, Tsukasa, Yamada, Hiroyoshi, Hirayama, Fukushi, Matsumoto, Yuzo, Yanagisawa, Isao
Published in Chemical & Pharmaceutical Bulletin (01.04.2005)
Published in Chemical & Pharmaceutical Bulletin (01.04.2005)
Get full text
Journal Article
Effects of Angiotensin II Type 1 Receptor Antagonist, YM358, on Cardiac Hypertrophy and Dysfunction after Myocardial Infarction in Rats
Tokioka-Akagi, Tomoko, Fujimori, Akira, Shibasaki, Masayuki, Matsuda-Satoh, Yasuko, Inagaki, Osamu, Yanagisawa, Isao
Published in Biological & pharmaceutical bulletin (01.07.2002)
Published in Biological & pharmaceutical bulletin (01.07.2002)
Get full text
Journal Article
Synthesis and Pharmacological Evaluation of 2-(3-Piperidyl)-1,2,3,4-tetrahydroisoquinoline Derivatives as Specific Bradycardic Agents
Kakefuda, Akio, Watanabe, Toshihiro, Taguchi, Yasuko, Masuda, Noriyuki, Tanaka, Akihiro, Yanagisawa, Isao
Published in Chemical & Pharmaceutical Bulletin (2003)
Published in Chemical & Pharmaceutical Bulletin (2003)
Get full text
Journal Article
Ethenesulfonamide Derivatives, a Novel Class of Orally Active Endothelin-A Receptor Antagonists
HARADA, Hironori, KAZAMI, Jun-ichi, WATANUKI, Susumu, TSUZUKI, Ryuji, SUDOH, Katsumi, FUJIMORI, Akira, TANAKA, Akihiro, TSUKAMOTO, Shin-ichi, YANAGISAWA, Isao
Published in Chemical & pharmaceutical bulletin (01.05.2001)
Published in Chemical & pharmaceutical bulletin (01.05.2001)
Get full text
Journal Article
Novel Potassium Channel Activators. III. Synthesis and Pharmacological Evaluation of 3, 4-Dihydro-2H-1, 4-benzoxazine Derivatives : Modification at the 2 Position
MATSUMOTO, Yuzo, UCHIDA, Wataru, NAKAHARA, Hideaki, YANAGISAWA, Isao, SHIBANUMA, Tadao, NOHIRA, Hiroyuki
Published in Chemical & pharmaceutical bulletin (2000)
Published in Chemical & pharmaceutical bulletin (2000)
Get full text
Journal Article
Novel Potassium Channel Activators : Synthesis and Structure-Activity Relationship Studies of 3, 4-Dihydro-2H-1, 4-benzoxazine Derivatives
MATSUMOTO, Yuzo, TSUZUKI, Ryuji, MATSUHISA, Akira, TAKAYAMA, Kazuhisa, YODEN, Toru, UCHIDA, Wataru, ASANO, Masaharu, FUJITA, Shigeo, YANAGISAWA, Isao, FUJIKURA, Takashi
Published in Chemical & pharmaceutical bulletin (01.01.1996)
Published in Chemical & pharmaceutical bulletin (01.01.1996)
Get full text
Journal Article
Novel potassium channel activators. II. Synthesis and pharmacological evaluation of 3,4-dihydro-2H-1,4-benzoxazine derivatives: Modification of the aromatic part
Matsumoto, Y, Tsuzuki, R, Matsuhisa, A, Masuda, N, Yamagiwa, Y, Yanagisawa, Shibanuma, T, Nohira, H
Published in Chemical & pharmaceutical bulletin (1999)
Published in Chemical & pharmaceutical bulletin (1999)
Get full text
Journal Article
Purification of a chitooligosaccharidolytic beta-N-acetylglucosaminidase from Bombyx mori larvae during metamorphosis and the nucleotide sequence of its cDNA
Nagamatsu, Y. (Hiroshima Univ., Fukuyama (Japan). Faculty of Applied Biological Science), Yanagisawa, I, Kimoto, M, Okamoto, E, Kogha, D
Published in Bioscience, biotechnology, and biochemistry (1995)
Published in Bioscience, biotechnology, and biochemistry (1995)
Get full text
Journal Article
Synthesis and Structure—Activity Relationships in a Series of Ethenesulfonamide Derivatives, a Novel Class of Endothelin Receptor Antagonists
HARADA, Hironori, KAZAMI, Jun-ichi, WATANUKI, Susumu, TSUZUKI, Ryuji, SUDOH, Katsumi, FUJIMORI, Akira, TOKUNAGA, Tatsuhiro, TANAKA, Akihiro, TSUKAMOTO, Shin-ichi, YANAGISAWA, Isao
Published in Chemical & pharmaceutical bulletin (2001)
Published in Chemical & pharmaceutical bulletin (2001)
Get full text
Journal Article
Antihypertensive activity of a nonpeptide angiotensin II receptor antagonist, YM358, in rats and dogs
Shibasaki, Masayuki, Fujimori, Akira, Kusayama, Toshiyuki, Tokioka, Tomoko, Satoh, Yasuko, Okazaki, Toshio, Uchida, Wataru, Inagaki, Osamu, Yanagisawa, Isao
Published in European journal of pharmacology (24.09.1997)
Published in European journal of pharmacology (24.09.1997)
Get full text
Journal Article
Effects of YM358, an Angiotensin II Type 1 (AT1) Receptor Antagonist, and Enalapril on Blood Pressure and Vasoconstriction in Two Renal Hypertension Models
TOKIOKA, Tomoko, SHIBASAKI, Masayuki, FUJIMORI, Akira, MATSUDA-SATOH, Yasuko, UCHIDA, Wataru, INAGAKI, Osamu, YANAGISAWA, Isao
Published in Biological & pharmaceutical bulletin (01.02.2000)
Published in Biological & pharmaceutical bulletin (01.02.2000)
Get full text
Journal Article