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Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia
Wang, Feng, Morita, Kiyomi, DiNardo, Courtney D., Furudate, Ken, Tanaka, Tomoyuki, Yan, Yuanqing, Patel, Keyur P., MacBeth, Kyle J., Wu, Bin, Liu, Guowen, Frattini, Mark, Matthews, Jairo A., Little, Latasha D., Gumbs, Curtis, Song, Xingzhi, Zhang, Jianhua, Thompson, Erika J., Kadia, Tapan M., Garcia-Manero, Guillermo, Jabbour, Elias, Ravandi, Farhad, Bhalla, Kapil N., Konopleva, Marina, Kantarjian, Hagop M., Andrew Futreal, P., Takahashi, Koichi
Published in Nature communications (10.05.2021)
Published in Nature communications (10.05.2021)
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PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy
Hsu, Joanne I., Dayaram, Tajhal, Tovy, Ayala, De Braekeleer, Etienne, Jeong, Mira, Wang, Feng, Zhang, Jianhua, Heffernan, Timothy P., Gera, Sonal, Kovacs, Jeffrey J., Marszalek, Joseph R., Bristow, Christopher, Yan, Yuanqing, Garcia-Manero, Guillermo, Kantarjian, Hagop, Vassiliou, George, Futreal, P. Andrew, Donehower, Lawrence A., Takahashi, Koichi, Goodell, Margaret A.
Published in Cell stem cell (01.11.2018)
Published in Cell stem cell (01.11.2018)
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Metabolic stress induces GD2+ cancer stem cell-like phenotype in triple-negative breast cancer
Jaggupilli, Appalaraju, Ly, Stanley, Nguyen, Khoa, Anand, Vivek, Yuan, Bin, El-Dana, Fouad, Yan, Yuanqing, Arvanitis, Zoe, Piyarathna, Danthasinghe Waduge Badrajee, Putluri, Nagireddy, Piwnica-Worms, Helen, Manning, Henry Charles, Andreeff, Michael, Battula, V. Lokesh
Published in British journal of cancer (09.03.2022)
Published in British journal of cancer (09.03.2022)
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ST8SIA1 Regulates Tumor Growth and Metastasis in TNBC by Activating the FAK–AKT–mTOR Signaling Pathway
Nguyen, Khoa, Yan, Yuanqing, Yuan, Bin, Dasgupta, Abhishek, Sun, Jeffrey, Mu, Hong, Do, Kim-Anh, Ueno, Naoto T., Andreeff, Michael, Battula, V. Lokesh
Published in Molecular cancer therapeutics (01.12.2018)
Published in Molecular cancer therapeutics (01.12.2018)
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Clearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia
Morita, Kiyomi, Kantarjian, Hagop M., Wang, Feng, Yan, Yuanqing, Bueso-Ramos, Carlos, Sasaki, Koji, Issa, Ghayas C., Wang, Sa, Jorgensen, Jeffrey, Song, Xingzhi, Zhang, Jianhua, Tippen, Samantha, Thornton, Rebecca, Coyle, Marcus, Little, Latasha, Gumbs, Curtis, Pemmaraju, Naveen, Daver, Naval, DiNardo, Courtney D., Konopleva, Marina, Andreeff, Michael, Ravandi, Farhad, Cortes, Jorge E., Kadia, Tapan, Jabbour, Elias, Garcia-Manero, Guillermo, Patel, Keyur P., Futreal, P. Andrew, Takahashi, Koichi
Published in Journal of clinical oncology (20.06.2018)
Published in Journal of clinical oncology (20.06.2018)
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Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics
Lu, Lina, Wang, Jennifer Rui, Henderson, Ying C., Bai, Shanshan, Yang, Jie, Hu, Min, Shiau, Cheng-Kai, Pan, Timothy, Yan, Yuanqing, Tran, Tuan M., Li, Jianzhuo, Kieser, Rachel, Zhao, Xiao, Wang, Jiping, Nurieva, Roza, Williams, Michelle D., Cabanillas, Maria E., Dadu, Ramona, Busaidy, Naifa Lamki, Zafereo, Mark, Navin, Nicholas, Lai, Stephen Y., Gao, Ruli
Published in The Journal of clinical investigation (01.06.2023)
Published in The Journal of clinical investigation (01.06.2023)
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High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors
Shiau, Cheng-Kai, Lu, Lina, Kieser, Rachel, Fukumura, Kazutaka, Pan, Timothy, Lin, Hsiao-Yun, Yang, Jie, Tong, Eric L., Lee, GaHyun, Yan, Yuanqing, Huse, Jason T., Gao, Ruli
Published in Nature communications (11.07.2023)
Published in Nature communications (11.07.2023)
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Cerebrospinal fluid ctDNA and metabolites are informative biomarkers for the evaluation of CNS germ cell tumors
Takayasu, Takeshi, Shah, Mauli, Dono, Antonio, Yan, Yuanqing, Borkar, Roshan, Putluri, Nagireddy, Zhu, Jay-Jiguang, Hama, Seiji, Yamasaki, Fumiyuki, Tahara, Hidetoshi, Sugiyama, Kazuhiko, Kurisu, Kaoru, Esquenazi, Yoshua, Ballester, Leomar Y.
Published in Scientific Reports (31.08.2020)
Published in Scientific Reports (31.08.2020)
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Bone marrow stromal cells induce an ALDH+ stem cell-like phenotype and enhance therapy resistance in AML through a TGF-β-p38-ALDH2 pathway
Yuan, Bin, El Dana, Fouad, Ly, Stanley, Yan, Yuanqing, Ruvolo, Vivian, Shpall, Elizabeth J., Konopleva, Marina, Andreeff, Michael, Battula, Venkata Lokesh
Published in PloS one (30.11.2020)
Published in PloS one (30.11.2020)
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NOTCH-Induced MDSC Recruitment after oHSV Virotherapy in CNS Cancer Models Modulates Antitumor Immunotherapy
Otani, Yoshihiro, Yoo, Ji Young, Lewis, Cole T., Chao, Samantha, Swanner, Jessica, Shimizu, Toshihiko, Kang, Jin Muk, Murphy, Sara A., Rivera-Caraballo, Kimberly, Hong, Bangxing, Glorioso, Joseph C., Nakashima, Hiroshi, Lawler, Sean E., Banasavadi-Siddegowda, Yeshavanth, Heiss, John D., Yan, Yuanqing, Pei, Guangsheng, Caligiuri, Michael A., Zhao, Zhongming, Chiocca, E. Antonio, Yu, Jianhua, Kaur, Balveen
Published in Clinical cancer research (01.04.2022)
Published in Clinical cancer research (01.04.2022)
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Characterization of genomic alterations in primary central nervous system lymphomas
Zorofchian, Soheil, El-Achi, Hanadi, Yan, Yuanqing, Esquenazi, Yoshua, Ballester, Leomar Y.
Published in Journal of neuro-oncology (01.12.2018)
Published in Journal of neuro-oncology (01.12.2018)
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Integrative genomic analysis of adult mixed phenotype acute leukemia delineates lineage associated molecular subtypes
Takahashi, Koichi, Wang, Feng, Morita, Kiyomi, Yan, Yuanqing, Hu, Peter, Zhao, Pei, Zhar, Abdallah Abou, Wu, Chang Jiun, Gumbs, Curtis, Little, Latasha, Tippen, Samantha, Thornton, Rebecca, Coyle, Marcus, Mendoza, Marisela, Thompson, Erika, Zhang, Jianhua, DiNardo, Courtney D., Jain, Nitin, Ravandi, Farhad, Cortes, Jorge E., Garcia-Manero, Guillermo, Kornblau, Steven, Andreeff, Michael, Jabbour, Elias, Bueso-Ramos, Carlos, Takaori-Kondo, Akifumi, Konopleva, Marina, Patel, Keyur, Kantarjian, Hagop, Futreal, P. Andrew
Published in Nature communications (10.07.2018)
Published in Nature communications (10.07.2018)
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Oncolytic HSV–Infected Glioma Cells Activate NOTCH in Adjacent Tumor Cells Sensitizing Tumors to Gamma Secretase Inhibition
Otani, Yoshihiro, Yoo, Ji Young, Chao, Samantha, Liu, Joseph, Jaime-Ramirez, Alena Cristina, Lee, Tae Jin, Hurwitz, Brian, Yan, Yuanqing, Dai, Hongsheng, Glorioso, Joseph C., Caligiuri, Michael A., Yu, Jianhua, Kaur, Balveen
Published in Clinical cancer research (15.05.2020)
Published in Clinical cancer research (15.05.2020)
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Oncolytic HSV Therapy Modulates Vesicular Trafficking Inducing Cisplatin Sensitivity and Antitumor Immunity
Hong, Bangxing, Chapa, Valerie, Saini, Uksha, Modgil, Puneet, Cohn, David E., He, Guangan, Siddik, Zahid H., Sood, Anil K., Yan, Yuanqing, Selvendiran, Karuppaiyah, Pei, Guangsheng, Zhao, Zhongming, Yoo, Ji Young, Kaur, Balveen
Published in Clinical cancer research (15.01.2021)
Published in Clinical cancer research (15.01.2021)
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Neurobehavioral Deficits After Subarachnoid Hemorrhage in Mice: Sensitivity Analysis and Development of a New Composite Score
Matsumura, Kanako, Kumar, T. Peeyush, Guddanti, Tejesh, Yan, Yuanqing, Blackburn, Spiros L., McBride, Devin W.
Published in Journal of the American Heart Association (16.04.2019)
Published in Journal of the American Heart Association (16.04.2019)
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IL-1β–dependent extravasation of preexisting lung-restricted autoantibodies during lung transplantation activates complement and mediates primary graft dysfunction
Yang, Wenbin, Cerier, Emily Jeong, Núñez-Santana, Félix L., Wu, Qiang, Yan, Yuanqing, Kurihara, Chitaru, Liu, Xianpeng, Yeldandi, Anjana, Khurram, Nigar, Avella-Patino, Diego, Sun, Haiying, Budinger, G.R. Scott, Kreisel, Daniel, Mohanakumar, Thalachallour, Lecuona, Emilia, Bharat, Ankit
Published in The Journal of clinical investigation (17.10.2022)
Published in The Journal of clinical investigation (17.10.2022)
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Inhibiting protein phosphatase 2A increases the antitumor effect of protein arginine methyltransferase 5 inhibition in models of glioblastoma
Otani, Yoshihiro, Sur, Hannah P, Rachaiah, Guruprasad, Namagiri, Sriya, Chowdhury, Ashis, Lewis, Cole T, Shimizu, Toshihiko, Gangaplara, Arunakumar, Wang, Xiang, Vézina, Amélie, Maric, Dragan, Jackson, Sadhana, Yan, Yuanqing, Zhengping, Zhuang, Ray-Chaudhury, Abhik, Kumar, Sachin, Ballester, Leomar Y, Chittiboina, Prashant, Yoo, Ji Young, Heiss, John, Kaur, Balveen, Banasavadi-Siddegowda, Yeshavanth Kumar
Published in Neuro-oncology (Charlottesville, Va.) (01.09.2021)
Published in Neuro-oncology (Charlottesville, Va.) (01.09.2021)
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