Early deficits in synaptic mitochondria in an Alzheimer’s disease mouse model
Du, Heng, Guo, Lan, Yan, Shiqiang, Sosunov, Alexander A., McKhann, Guy M., Yan, Shirley ShiDu, Cuatrecasas, Pedro M.
Published in Proceedings of the National Academy of Sciences - PNAS (26.10.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (26.10.2010)
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Journal Article
Astrocytes Attenuate Mitochondrial Dysfunctions in Human Dopaminergic Neurons Derived from iPSC
Du, Fang, Yu, Qing, Chen, Allen, Chen, Doris, Yan, Shirley ShiDu
Published in Stem cell reports (13.02.2018)
Published in Stem cell reports (13.02.2018)
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Journal Article
Mitochondrial permeability transition pore is a potential drug target for neurodegeneration
Rao, Valasani Koteswara, Carlson, Emily A., Yan, Shirley Shidu
Published in Biochimica et biophysica acta (01.08.2014)
Published in Biochimica et biophysica acta (01.08.2014)
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Journal Article
Hypertension Induces Brain β-Amyloid Accumulation, Cognitive Impairment, and Memory Deterioration Through Activation of Receptor for Advanced Glycation End Products in Brain Vasculature
Carnevale, Daniela, Mascio, Giada, DʼAndrea, Ivana, Fardella, Valentina, Bell, Robert D, Branchi, Igor, Pallante, Fabio, Zlokovic, Berislav, Yan, Shirley ShiDu, Lembo, Giuseppe
Published in Hypertension (Dallas, Tex. 1979) (01.07.2012)
Published in Hypertension (Dallas, Tex. 1979) (01.07.2012)
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Journal Article
Drp1-mediated mitochondrial abnormalities link to synaptic injury in diabetes model
Huang, Shengbin, Wang, Yongfu, Gan, Xueqi, Fang, Du, Zhong, Changjia, Wu, Long, Hu, Gang, Sosunov, Alexander A, McKhann, Guy M, Yu, Haiyang, Yan, Shirley ShiDu
Published in Diabetes (New York, N.Y.) (01.05.2015)
Published in Diabetes (New York, N.Y.) (01.05.2015)
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Journal Article
Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell
Gan, Xueqi, Huang, Shengbin, Wu, Long, Wang, Yongfu, Hu, Gang, Li, Guangyue, Zhang, Hongju, Yu, Haiyang, Swerdlow, Russell Howard, Chen, John Xi, Yan, Shirley ShiDu
Published in Biochimica et biophysica acta (01.02.2014)
Published in Biochimica et biophysica acta (01.02.2014)
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Journal Article
Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease
Yu, Qing, Wang, Yongfu, Du, Fang, Yan, Shijun, Hu, Gang, Origlia, Nicola, Rutigliano, Grazia, Sun, Qinru, Yu, Haiyang, Ainge, James, Yan, Shi Fang, Gunn-Moore, Frank, Yan, Shirley ShiDu
Published in Nature communications (30.07.2018)
Published in Nature communications (30.07.2018)
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Journal Article
High Dietary Advanced Glycation End Products Impair Mitochondrial and Cognitive Function
Akhter, Firoz, Chen, Doris, Akhter, Asma, Sosunov, Alexander A, Chen, Allen, McKhann, Guy M, Yan, Shi Fang, Yan, Shirley ShiDu
Published in Journal of Alzheimer's disease (01.01.2020)
Published in Journal of Alzheimer's disease (01.01.2020)
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Journal Article
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction
Takuma, Kazuhiro, Fang, Fang, Zhang, Wensheng, Yan, Shiqiang, Fukuzaki, Emiko, Du, Heng, Sosunov, Alexander, McKhann, Guy, Funatsu, Yoko, Nakamichi, Noritaka, Nagai, Taku, Mizoguchi, Hiroyuki, Ibi, Daisuke, Hori, Osamu, Ogawa, Satoshi, Stern, David M, Yamada, Kiyofumi, Yan, Shirley ShiDu
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2009)
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Journal Article
Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons
Guo, Lan, Du, Heng, Yan, Shiqiang, Wu, Xiaoping, McKhann, Guy M, Chen, John Xi, Yan, Shirley ShiDu
Published in PloS one (31.01.2013)
Published in PloS one (31.01.2013)
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Journal Article
Identification of a Small Molecule Cyclophilin D Inhibitor for Rescuing Aβ-Mediated Mitochondrial Dysfunction
Valasani, Koteswara Rao, Sun, Qinru, Fang, Du, Zhang, Zhihua, Yu, Qing, Guo, Yaopeng, Li, Jianping, Roy, Anuradha, ShiDu Yan, Shirley
Published in ACS medicinal chemistry letters (10.03.2016)
Published in ACS medicinal chemistry letters (10.03.2016)
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Journal Article
ABAD Directly Links Aβ to Mitochondrial Toxicity in Alzheimer's Disease
Lustbader, Joyce W., Cirilli, Maurizio, Lin, Chang, Xu, Hong Wei, Takuma, Kazuhiro, Wang, Ning, Caspersen, Casper, Chen, Xi, Pollak, Susan, Chaney, Michael, Trinchese, Fabrizio, Liu, Shumin, Gunn-Moore, Frank, Lue, Lih-Fen, Walker, Douglas G., Kuppusamy, Periannan, Zewier, Zay L., Arancio, Ottavio, Stern, David, Yan, Shirley ShiDu, Wu, Hao
Published in Science (American Association for the Advancement of Science) (16.04.2004)
Published in Science (American Association for the Advancement of Science) (16.04.2004)
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