A New Class of Safe, Potent, and Specific P‑gp Modulator: Flavonoid Dimer FD18 Reverses P‑gp-Mediated Multidrug Resistance in Human Breast Xenograft in Vivo
Yan, Clare S. W, Wong, Iris L. K, Chan, Kin-Fai, Kan, Jason W. Y, Chong, Tsz Cheung, Law, Man Chun, Zhao, Yunzhe, Chan, Shun Wan, Chan, Tak Hang, Chow, Larry M. C
Published in Molecular pharmaceutics (05.10.2015)
Published in Molecular pharmaceutics (05.10.2015)
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Discovery of a Flavonoid FM04 as a Potent Inhibitor to Reverse P-Glycoprotein-Mediated Drug Resistance in Xenografts and Improve Oral Bioavailability of Paclitaxel
Kan, Jason W Y, Yan, Clare S W, Wong, Iris L K, Su, Xiaochun, Liu, Zhen, Chan, Tak Hang, Chow, Larry M C
Published in International journal of molecular sciences (04.12.2022)
Published in International journal of molecular sciences (04.12.2022)
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Flavonoid Dimers as Bivalent Modulators for P-Glycoprotein-Based Multidrug Resistance: Structure-Activity Relationships
Chan, Kin-Fai, Zhao, Yunzhe, Chow, Toby W. S., Yan, Clare S. W., Ma, Dik Lung, Burkett, Brendan A., Wong, Iris L. K., Chow, Larry M. C., Chan, Tak Hang
Published in ChemMedChem (17.04.2009)
Published in ChemMedChem (17.04.2009)
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Characterization of a Potent, Selective, and Safe Inhibitor, Ac15(Az8)2, in Reversing Multidrug Resistance Mediated by Breast Cancer Resistance Protein (BCRP/ABCG2)
Chong, Tsz Cheung, Wong, Iris L. K., Cui, Jiahua, Law, Man Chun, Zhu, Xuezhen, Hu, Xuesen, Kan, Jason W. Y., Yan, Clare S. W., Chan, Tak Hang, Chow, Larry M. C.
Published in International journal of molecular sciences (31.10.2022)
Published in International journal of molecular sciences (31.10.2022)
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Amine Linked Flavonoid Dimers as Modulators for P-Glycoprotein-Based Multidrug Resistance: Structure–Activity Relationship and Mechanism of Modulation
Chan, Kin-Fai, Wong, Iris L. K, Kan, Jason W. Y, Yan, Clare S. W, Chow, Larry M. C, Chan, Tak Hang
Published in Journal of medicinal chemistry (08.03.2012)
Published in Journal of medicinal chemistry (08.03.2012)
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Design and Syntheses of Permethyl Ningalin B Analogues: Potent Multidrug Resistance (MDR) Reversal Agents of Cancer Cells
Zhang, Pu Yong, Wong, Iris L. K, Yan, Clare S. W, Zhang, Xiao Yu, Jiang, Tao, Chow, Larry M. C, Wan, Sheng Biao
Published in Journal of medicinal chemistry (22.07.2010)
Published in Journal of medicinal chemistry (22.07.2010)
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Identification of Binding Sites in the Nucleotide-Binding Domain of P‑Glycoprotein for a Potent and Nontoxic Modulator, the Amine-Containing Monomeric Flavonoid FM04
Liu, Zhen, Wong, Iris L. K., Sang, Jingcheng, Liu, Fufeng, Yan, Clare S. W., Kan, Jason W. Y., Chan, Tak Hang, Chow, Larry M. C.
Published in Journal of medicinal chemistry (11.05.2023)
Published in Journal of medicinal chemistry (11.05.2023)
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