A patatin‐like phospholipase functions during gametocyte induction in the malaria parasite Plasmodium falciparum
Flammersfeld, Ansgar, Panyot, Atscharah, Yamaryo‐Botté, Yoshiki, Aurass, Philipp, Przyborski, Jude M., Flieger, Antje, Botté, Cyrille, Pradel, Gabriele
Published in Cellular microbiology (01.03.2020)
Published in Cellular microbiology (01.03.2020)
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PI4‐kinase and PfCDPK7 signaling regulate phospholipid biosynthesis in Plasmodium falciparum
Maurya, Ranjana, Tripathi, Anuj, Kumar, Manish, Antil, Neelam, Yamaryo‐Botté, Yoshiki, Kumar, Praveen, Bansal, Priyanka, Doerig, Christian, Botté, Cyrille Y, Prasad, T S Keshava, Sharma, Pushkar
Published in EMBO reports (03.02.2022)
Published in EMBO reports (03.02.2022)
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Phosphatidic Acid-Mediated Signaling Regulates Microneme Secretion in Toxoplasma
Bullen, Hayley E., Jia, Yonggen, Yamaryo-Botté, Yoshiki, Bisio, Hugo, Zhang, Ou, Jemelin, Natacha Klages, Marq, Jean-Baptiste, Carruthers, Vern, Botté, Cyrille Y., Soldati-Favre, Dominique
Published in Cell host & microbe (09.03.2016)
Published in Cell host & microbe (09.03.2016)
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Toxoplasma gondii acetyl-CoA synthetase is involved in fatty acid elongation (of long fatty acid chains) during tachyzoite life stages
Dubois, David, Fernandes, Stella, Amiar, Souad, Dass, Sheena, Katris, Nicholas J., Botté, Cyrille Y., Yamaryo-Botté, Yoshiki
Published in Journal of lipid research (01.06.2018)
Published in Journal of lipid research (01.06.2018)
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Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage
Dass, Sheena, Shunmugam, Serena, Berry, Laurence, Arnold, Christophe-Sebastien, Katris, Nicholas J., Duley, Samuel, Pierrel, Fabien, Cesbron-Delauw, Marie-France, Yamaryo-Botté, Yoshiki, Botté, Cyrille Y.
Published in Nature communications (17.05.2021)
Published in Nature communications (17.05.2021)
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Variation in Lipid Species Profiles among Leukemic Cells Significantly Impacts Their Sensitivity to the Drug Targeting of Lipid Metabolism and the Prognosis of AML Patients
Lo Presti, Caroline, Yamaryo-Botté, Yoshiki, Mondet, Julie, Berthier, Sylvie, Nutiu, Denisa, Botté, Cyrille, Mossuz, Pascal
Published in International journal of molecular sciences (22.03.2023)
Published in International journal of molecular sciences (22.03.2023)
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Coupling of lysosomal and mitochondrial membrane permeabilization in trypanolysis by APOL1
Vanwalleghem, Gilles, Fontaine, Frédéric, Lecordier, Laurence, Tebabi, Patricia, Klewe, Kristoffer, Nolan, Derek P., Yamaryo-Botté, Yoshiki, Botté, Cyrille, Kremer, Anneke, Burkard, Gabriela Schumann, Rassow, Joachim, Roditi, Isabel, Pérez-Morga, David, Pays, Etienne
Published in Nature communications (26.08.2015)
Published in Nature communications (26.08.2015)
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ALA10, a Phospholipid Flippase, Controls FAD2/FAD3 Desaturation of Phosphatidylcholine in the ER and Affects Chloroplast Lipid Composition in Arabidopsis thaliana
Botella, César, Sautron, Emeline, Boudiere, Laurence, Michaud, Morgane, Dubots, Emmanuelle, Yamaryo-Botté, Yoshiki, Albrieux, Catherine, Marechal, Eric, Block, Maryse A., Jouhet, Juliette
Published in Plant physiology (Bethesda) (01.03.2016)
Published in Plant physiology (Bethesda) (01.03.2016)
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Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation
Dass, Sheena, Shunmugam, Serena, Charital, Sarah, Duley, Samuel, Arnold, Christophe-Sébastien, Katris, Nicholas J., Cavaillès, Pierre, Cesbron-Delauw, Marie-France, Yamaryo-Botté, Yoshiki, Botté, Cyrille Y.
Published in Journal of lipid research (01.10.2024)
Published in Journal of lipid research (01.10.2024)
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An essential vesicular-trafficking phospholipase mediates neutral lipid synthesis and contributes to hemozoin formation in Plasmodium falciparum
Asad, Mohd, Yamaryo-Botté, Yoshiki, Hossain, Mohammad E, Thakur, Vandana, Jain, Shaifali, Datta, Gaurav, Botté, Cyrille Y, Mohmmed, Asif
Published in BMC biology (11.08.2021)
Published in BMC biology (11.08.2021)
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Journal Article
Protein kinase TgCDPK7 regulates vesicular trafficking and phospholipid synthesis in Toxoplasma gondii
Bansal, Priyanka, Antil, Neelam, Kumar, Manish, Yamaryo-Botté, Yoshiki, Rawat, Rahul Singh, Pinto, Sneha, Datta, Keshava K, Katris, Nicholas J, Botté, Cyrille Y, Prasad, T S Keshava, Sharma, Pushkar
Published in PLoS pathogens (01.02.2021)
Published in PLoS pathogens (01.02.2021)
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CRISPR Screens Identify Toxoplasma Genes That Determine Parasite Fitness in Interferon Gamma-Stimulated Human Cells
Krishnamurthy, Shruthi, Maru, Parag, Wang, Yifan, Bitew, Mebratu A, Mukhopadhyay, Debanjan, Yamaryo-Botté, Yoshiki, Paredes-Santos, Tatiana C, Sangaré, Lamba O, Swale, Christopher, Botté, Cyrille Y, Saeij, Jeroen P J
Published in mBio (25.04.2023)
Published in mBio (25.04.2023)
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Journal Article
Division and Adaptation to Host Environment of Apicomplexan Parasites Depend on Apicoplast Lipid Metabolic Plasticity and Host Organelle Remodeling
Amiar, Souad, Katris, Nicholas J., Berry, Laurence, Dass, Sheena, Duley, Samuel, Arnold, Christophe-Sebastien, Shears, Melanie J., Brunet, Camille, Touquet, Bastien, McFadden, Geoffrey I., Yamaryo-Botté, Yoshiki, Botté, Cyrille Y.
Published in Cell reports (Cambridge) (17.03.2020)
Published in Cell reports (Cambridge) (17.03.2020)
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Long-term intermittent hypoxia in mice induces inflammatory pathways implicated in sleep apnea and steatohepatitis in humans
Gaucher, Jonathan, Montellier, Emilie, Vial, Guillaume, Chuffart, Florent, Guellerin, Maëlle, Bouyon, Sophie, Lemarie, Emeline, Yamaryo-Botté, Yoshiki, Dirani, Aya, Ben Messaoud, Raoua, Faure, Marie Joyeux, Ribuot, Diane Godin, Costentin, Charlotte, Tamisier, Renaud, Botté, Cyrille Y., Khochbin, Saadi, Rousseaux, Sophie, Pépin, Jean-Louis
Published in iScience (16.02.2024)
Published in iScience (16.02.2024)
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Atypical lipid composition in the purified relict plastid (apicoplast) of malaria parasites
Botté, Cyrille Y., Yamaryo-Botté, Yoshiki, Rupasinghe, Thusitha W. T., Mullin, Kylie A., MacRae, James I., Spurck, Timothy P., Kalanon, Ming, Shears, Melanie J., Coppel, Ross L., Crellin, Paul K., Maréchal, Eric, McConville, Malcolm J., McFadden, Geoffrey I.
Published in Proceedings of the National Academy of Sciences - PNAS (30.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (30.04.2013)
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The acyl-CoA synthetase TgACS1 allows neutral lipid metabolism and extracellular motility in Toxoplasma gondii through relocation via its peroxisomal targeting sequence (PTS) under low nutrient conditions
Charital, Sarah, Shunmugam, Serena, Dass, Sheena, Alazzi, Anna Maria, Arnold, Christophe-Sébastien, Katris, Nicholas J., Duley, Samuel, Quansah, Nyamekye A., Pierrel, Fabien, Govin, Jérôme, Yamaryo-Botté, Yoshiki, Botté, Cyrille Y.
Published in mBio (10.04.2024)
Published in mBio (10.04.2024)
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Journal Article
The patatin-like phospholipase PfPNPLA2 is involved in the mitochondrial degradation of phosphatidylglycerol during Plasmodium falciparum blood stage development
Shunmugam, Serena, Quansah, Nyamekye, Flammersfeld, Ansgar, Islam, Md Muzahidul, Sassmannshausen, Juliane, Bennink, Sandra, Yamaryo-Botté, Yoshiki, Pradel, Gabriele, Botté, Cyrille Y.
Published in Frontiers in cellular and infection microbiology (20.11.2023)
Published in Frontiers in cellular and infection microbiology (20.11.2023)
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Apicoplast-Localized Lysophosphatidic Acid Precursor Assembly Is Required for Bulk Phospholipid Synthesis in Toxoplasma gondii and Relies on an Algal/Plant-Like Glycerol 3-Phosphate Acyltransferase
Amiar, Souad, MacRae, James I, Callahan, Damien L, Dubois, David, van Dooren, Giel G, Shears, Melanie J, Cesbron-Delauw, Marie-France, Maréchal, Eric, McConville, Malcolm J, McFadden, Geoffrey I, Yamaryo-Botté, Yoshiki, Botté, Cyrille Y
Published in PLoS pathogens (01.08.2016)
Published in PLoS pathogens (01.08.2016)
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Journal Article
TgPL2, a patatin‐like phospholipase domain‐containing protein, is involved in the maintenance of apicoplast lipids homeostasis in Toxoplasma
Lévêque, Maude F., Berry, Laurence, Yamaryo‐Botté, Yoshiki, Nguyen, Hoa Mai, Galera, Marine, Botté, Cyrille Y., Besteiro, Sébastien
Published in Molecular microbiology (01.07.2017)
Published in Molecular microbiology (01.07.2017)
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Journal Article
Activation of the Chloroplast Monogalactosyldiacylglycerol Synthase MGD1 by Phosphatidic Acid and Phosphatidylglycerol
Dubots, Emmanuelle, Audry, Magali, Yamaryo, Yoshiki, Bastien, Olivier, Ohta, Hiroyuki, Breton, Christelle, Maréchal, Eric, Block, Maryse A.
Published in The Journal of biological chemistry (26.02.2010)
Published in The Journal of biological chemistry (26.02.2010)
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