Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis
Banerji, Aleena, Busse, Paula, Shennak, Mustafa, Lumry, William, Davis-Lorton, Mark, Wedner, Henry J, Jacobs, Joshua, Baker, James, Bernstein, Jonathan A, Lockey, Richard, Li, H. Henry, Craig, Timothy, Cicardi, Marco, Riedl, Marc, Al-Ghazawi, Ahmad, Soo, Carolyn, Iarrobino, Ryan, Sexton, Daniel J, TenHoor, Christopher, Kenniston, Jon A, Faucette, Ryan, Still, J. Gordon, Kushner, Harvey, Mensah, Robert, Stevens, Chris, Biedenkapp, Joseph C, Chyung, Yung, Adelman, Burt
Published in The New England journal of medicine (23.02.2017)
Published in The New England journal of medicine (23.02.2017)
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Journal Article
Ecallantide for the Acute Treatment of Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema: A Multicenter, Randomized, Controlled Trial
Lewis, Lawrence M., MD, Graffeo, Charles, MD, Crosley, Pascal, DO, Klausner, Howard A., MD, Clark, Carol L., MD, Frank, Anthony, MD, Miner, James, MD, Iarrobino, Ryan, BA, Chyung, Yung, MD
Published in Annals of emergency medicine (01.02.2015)
Published in Annals of emergency medicine (01.02.2015)
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A Randomized Phase 1 Safety, Pharmacokinetic and Pharmacodynamic Study of the Novel Myostatin Inhibitor Apitegromab (SRK-015): A Potential Treatment for Spinal Muscular Atrophy
Barrett, Doreen, Bilic, Sanela, Chyung, Yung, Cote, Shaun M., Iarrobino, Ryan, Kacena, Katherine, Kalra, Ashish, Long, Kimberly, Nomikos, George, Place, Amy, Still, James Gordon, Vrishabhendra, Leela
Published in Advances in therapy (01.06.2021)
Published in Advances in therapy (01.06.2021)
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A phase 1 study investigating DX-2930 in healthy subjects
Chyung, Yung, MD, Vince, Bradley, DO, Iarrobino, Ryan, BA, Sexton, Dan, PhD, Kenniston, Jon, PhD, Faucette, Ryan, BS, TenHoor, Chris, PharmD, PhD, Stolz, Leslie E., PhD, Stevens, Chris, MD, Biedenkapp, Joseph, PhD, Adelman, Burt, MD
Published in Annals of allergy, asthma, & immunology (01.10.2014)
Published in Annals of allergy, asthma, & immunology (01.10.2014)
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Hereditary Angioedema Is Associated with Neuropathic Pain, Systemic Lupus Erythematosis and Systemic Mastocytosis in an Analysis of a Health Analytics Claims Database
Stevens, Chris, Biedenkapp, Joseph C, Mensah, Robert, Chyung, Yung H, Adelman, Burt
Published in Journal of allergy and clinical immunology (01.02.2016)
Published in Journal of allergy and clinical immunology (01.02.2016)
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Journal Article
Characterization of anaphylaxis after ecallantide treatment of hereditary angioedema attacks
Craig, Timothy J, Li, H Henry, Riedl, Marc, Bernstein, Jonathan A, Lumry, William R, MacGinnitie, Andrew J, Stolz, Leslie E, Biedenkapp, Joseph, Chyung, Yung
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01.03.2015)
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01.03.2015)
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Comparison Of Plasma Kallikrein Inhibition By The Monoclonal Antibody Inhibitor DX-2930 To Endogenous C1-INH
Sexton, Daniel, Kenniston, Jon, Faucette, Ryan, Nixon, Andrew, TenHoor, Christopher, Chyung, Yung H, Adelman, Burt
Published in Journal of allergy and clinical immunology (01.02.2014)
Published in Journal of allergy and clinical immunology (01.02.2014)
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Journal Article
Refined Method for Collection of Plasma Samples to Evaluate the Role of Plasma Kallikrein in Various Disease States
Bernstein, Jonathan A., MD, Wedner, H. James, MD FAAAAI, Busse, Paula J., MD FAAAAI, Banerji, Aleena, MD, Cicardi, Marco, Sufritti, C, Brooks, Edward G., MD, Cheifitz, Adam, Schwartz, Lawrence B., MD PhD FAAAAI, Akin, Cem, MD PhD FAAAAI, Sexton, Daniel, Stevens, Chris, Stolz, Leslie E, Viswanathan, Malini, Faucette, Ryan, Biedenkapp, Joseph C, Chyung, Yung H, Adelman, Burt
Published in Journal of allergy and clinical immunology (01.02.2016)
Published in Journal of allergy and clinical immunology (01.02.2016)
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Journal Article
Pharmacodynamic Effect of DX-2930 on Plasma Kallikrein in Hereditary Angioedema Patients
Davis-Lorton, Mark A., MD FAAAAI, Busse, Paula J., MD FAAAAI, Banerji, Aleena, MD, Shennak, Mustafa, Lumry, William R., MD FAAAAI, Wedner, H. James, MD FAAAAI, Jacobs, Joshua S., MD, Baker, James W., MD FAAAAI, Bernstein, Jonathan A., MD, Lockey, Richard F., MD, Li, H. Henry, MD PhD, Craig, Timothy J, Cicardi, Marco, Riedl, Marc A., MD MS, Al-Ghazawi, Ahmad, Soo, Carolyn, Iarrobino, Ryan, Sexton, Daniel, TenHoor, Christopher, Faucette, Ryan, Biedenkapp, Joseph C, Chyung, Yung H, Adelman, Burt
Published in Journal of allergy and clinical immunology (01.02.2016)
Published in Journal of allergy and clinical immunology (01.02.2016)
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Relationship Between Drug Exposure and Clinical Response Observed in the Phase 1b Study of DX-2930 in Subjects with Hereditary Angioedema
Jacobs, Joshua S., MD, Busse, Paula J., MD FAAAAI, Banerji, Aleena, MD, Shennak, Mustafa, Lumry, William R., MD FAAAAI, Davis-Lorton, Mark A., MD FAAAAI, Wedner, H. James, MD FAAAAI, Baker, James W., MD FAAAAI, Bernstein, Jonathan A., MD, Lockey, Richard F., MD, Li, H. Henry, MD PhD, Craig, Timothy J, Cicardi, Marco, Riedl, Marc A., MD MS, Al-Ghazawi, Ahmad, Soo, Carolyn, Iarrobino, Ryan, Sexton, Daniel, TenHoor, Christopher, Faucette, Ryan, Biedenkapp, Joseph C, Chyung, Yung H, Adelman, Burt
Published in Journal of allergy and clinical immunology (01.02.2016)
Published in Journal of allergy and clinical immunology (01.02.2016)
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Modeling and Analyses to Identify Potential Dosing Regimens of DX-2930 for the Long-Term Prophylaxis of Hereditary Angioedema
Wedner, H. James, MD FAAAAI, Busse, Paula J., MD FAAAAI, Banerji, Aleena, MD, Shennak, Mustafa, Lumry, William R., MD FAAAAI, Davis-Lorton, Mark A., MD FAAAAI, Jacobs, Joshua S., MD, Baker, James W., MD FAAAAI, Bernstein, Jonathan A., MD, Lockey, Richard F., MD, Li, H. Henry, MD PhD, Craig, Timothy J, Cicardi, Marco, Riedl, Marc A., MD MS, Al-Ghazawi, Ahmad, Soo, Carolyn, Iarrobino, Ryan, Sexton, Daniel, TenHoor, Christopher, Faucette, Ryan, Biedenkapp, Joseph C, Chyung, Yung H, Adelman, Burt
Published in Journal of allergy and clinical immunology (01.02.2016)
Published in Journal of allergy and clinical immunology (01.02.2016)
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Characterization of a Protein Complex Containing Spliceosomal Proteins SAPs 49, 130, 145, and 155
Das, Biplab K., Xia, Ling, Palandjian, Leon, Gozani, Or, Chyung, Yung, Reed, Robin
Published in Molecular and Cellular Biology (01.10.1999)
Published in Molecular and Cellular Biology (01.10.1999)
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Safety and Efficacy of Apitegromab in Patients With Spinal Muscular Atrophy Types 2 and 3: The Phase 2 TOPAZ Study
Crawford, Thomas O, Darras, Basil T, Day, John W, Dunaway Young, Sally, Duong, Tina, Nelson, Leslie L, Barrett, Doreen, Song, Guochen, Bilic, Sanela, Cote, Shaun, Sadanowicz, Mara, Iarrobino, Ryan, Xu, Tiina J, O'Neil, Janet, Rossello, José, Place, Amy, Kertesz, Nathalie, Nomikos, George, Chyung, Yung
Published in Neurology (12.03.2024)
Published in Neurology (12.03.2024)
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Journal Article
Safety and Efficacy of Apitegromab in Patients With Spinal Muscular Atrophy Types 2 and 3: The Phase 2 TOPAZ Study
Published in Neurology
(09.07.2024)
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Relationship of pharmacokinetics and pharmacodynamics to apitegromab efficacy in patients with later-onset spinal muscular atrophy (Types 2 and 3 SMA): Results from the TOPAZ study
Crawford, Thomas, Place, Amy, Barrett, Doreen, Cote, Shaun, Nomikos, George, Song, Guochen, Bilic, Sanela, Kalra, Ashish, Sadanowicz, Mara, O'Neil, Janet, Iarrobino, Ryan, Kertesz, Nathalie, Chyung, Yung
Published in Journal of the neurological sciences (01.10.2021)
Published in Journal of the neurological sciences (01.10.2021)
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First-in-human phase 1 trial (DRAGON) of SRK-181, a potential first-in-class selective latent TGFβ1 inhibitor, alone or in combination with anti-PD-(L)1 treatment in patients with advanced solid tumors
Yap, Timothy A., Barve, Minal A., Gainor, Justin F., Weekes, Colin D., Bockorny, Bruno, Ju, Yawen, Faucette, Ryan, Bilic, Sanela, Lee-Hoeflich, Si Tuen, Song, Guochen, Chyung, Yung, Legler, Michelle, Gan, Lu, Bendell, Johanna C.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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