AML-144 Uroporphyrinogen Decarboxylase (UROD) Is a Therapeutically Targetable Dependency in Acute Erythroid Leukemia
Friske, Jake, Fukuda, Yu, Backhaus, Emily, Baviskar, Prady, Benini, Francesca, Connelly, Jon, Klein, Jonathon, Cunningham, Trevor, Yu, Jiyang, Pruett-Miller, Shondra, Schuetz, John, Mullighan, Charles, lacobucci, Ilaira
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
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Poster: AML-144 Uroporphyrinogen Decarboxylase (UROD) Is a Therapeutically Targetable Dependency in Acute Erythroid Leukemia
Friske, Jake, Fukuda, Yu, Backhaus, Emily, Baviskar, Prady, Benini, Francesca, Connelly, Jon, Klein, Jonathon, Cunningham, Trevor, Yu, Jiyang, Pruett-Miller, Shondra, Schuetz, John, Mullighan, Charles, Iacobucci, Ilaira
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
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The miR-424(322)/503 gene cluster regulates pro- versus anti-inflammatory skin DC subset differentiation by modulating TGF-β signaling
Zyulina, Victoria, Yan, Koon-Kiu, Ju, Bensheng, Schwarzenberger, Elke, Passegger, Christina, Tam-Amersdorfer, Carmen, Pan, Qingfei, Sconocchia, Tommaso, Pollack, Christian, Shaner, Bridget, Zebisch, Armin, Easton, John, Yu, Jiyang, Silva, Jose M., Strobl, Herbert
Published in Cell reports (Cambridge) (27.04.2021)
Published in Cell reports (Cambridge) (27.04.2021)
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Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death
Tosello, Valeria, Saccomani, Valentina, Yu, Jiyang, Bordin, Fulvio, Amadori, Alberto, Piovan, Erich
Published in Oncotarget (19.07.2016)
Published in Oncotarget (19.07.2016)
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Breast Cancer Cells Respond Differentially to Modulation of TGF beta 2 Signaling after Exposure to Chemotherapy or Hypoxia
O'Brien, Siobhan K, Chen, Liang, Zhong, Wenyan, Armellino, Douglas, Yu, Jiyang, Loreth, Christine, Follettie, Maximillian, Damelin, Marc
Published in Cancer research (Chicago, Ill.) (01.11.2015)
Published in Cancer research (Chicago, Ill.) (01.11.2015)
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Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia
Gocho, Yoshihiro, Liu, Jingjing, Hu, Jianzhong, Yang, Wentao, Dharia, Neekesh V, Zhang, Jingliao, Shi, Hao, Du, Guoqing, John, August, Lin, Ting-Nien, Hunt, Jeremy, Huang, Xin, Ju, Bensheng, Rowland, Lauren, Shi, Lei, Maxwell, Dylan, Smart, Brandon, Crews, Kristine R, Yang, Wenjian, Hagiwara, Kohei, Zhang, Yingchi, Roberts, Kathryn, Wang, Hong, Jabbour, Elias, Stock, Wendy, Eisfelder, Bartholomew, Paietta, Elisabeth, Newman, Scott, Roti, Giovanni, Litzow, Mark, Easton, John, Zhang, Jinghui, Peng, Junmin, Chi, Hongbo, Pounds, Stanley, Relling, Mary V, Inaba, Hiroto, Zhu, Xiaofan, Kornblau, Steven, Pui, Ching-Hon, Konopleva, Marina, Teachey, David, Mullighan, Charles G, Stegmaier, Kimberly, Evans, William E, Yu, Jiyang, Yang, Jun J
Published in Nature cancer (01.03.2021)
Published in Nature cancer (01.03.2021)
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An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling
Wijaya, Juwina, Vo, BaoHan T, Liu, Jingjing, Xu, Beisi, Wu, Gang, Wang, Yao, Peng, Junmin, Zhang, Jin, Janke, Laura J, Orr, Brent A, Yu, Jiyang, Roussel, Martine F, Schuetz, John D
Published in Cancer research (Chicago, Ill.) (01.04.2020)
Published in Cancer research (Chicago, Ill.) (01.04.2020)
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Development of a Lumped Parameter Dynamic Degassing Model for Spray-Heating Degasser and Its Application in the Pressurizer of a Pressurized Water Reactor
Zhong, Xianping, Yu, Jiyang, Zhang, Xiaolong, Saeed, Muhammad, Li, Yi, Chen, Zhihui, Tang, Bin, Sun, Yan, Huang, Tao
Published in Nuclear technology (01.02.2021)
Published in Nuclear technology (01.02.2021)
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Abstract P1-19-27: Phase IB trial of ACY-1215 (ricolinostat) combined with nab-paclitaxel in metastatic breast cancer (MBC)
Kalinsky, Kevin, Chiuzan, Cody, Onishi, Maika, Trivedi, Meghna S, Accordino, Melissa, Zeleke, Tizita, Pan, Qingfei, Kelly, Sean, Honan, Erin, Wu, Ruby, Fenn, Kathleen, Crew, Katherin D, Hershman, Dawn L, Maurer, Matthew, Yu, Jiyang, Silva, Jose
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Abstract 1543: Mining cancer-specific isoforms as CAR T-cell therapy targets for pediatric solid and brain tumors
Shaw, Timothy I., Wagner, Jessica, Wickman, Elizabeth, Tian, Liqing, Li, Dong, Poudel, Suresh, Stewart, Elizabeth, Li, Yuxin, Wang, Hong, Niu, Mingming, Paul, Robin, Reilly, Colleen, Zhou, Xin, Dyer, Michael, Baker, Suzanne, Peng, Junmin, Yu, Jiyang, Velasquez, Paulina, DeRenzo, Chris, Krenciute, Giedre, Zhang, Jinghui, Gottschalk, Stephen
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 645: Network-based assessment of HDAC6 activity is highly predictive of pre-clinical and clinical responses to the HDAC6 inhibitor ricolinostat
Pan, Qingfei, Zeleke, Tizita, Chiuzan, Cody, Onishi, Maika, Alvarez, Mariano, Honan, Erin, Yang, Min, Chia, Pei Ling, Mukhopadhyay, Partha, Kelly, Sean, Wu, Ruby, Fenn, Kathleen, Trivedi, Meghna, Accordino, Melissa, Crew, Katherine, Hershman, Dawn, Maurer, Matthew, Jones, Simon, Califano, Andrea, Kalinsky, Kevin, Yu, Jiyang, Silva, Jose
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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An ABC transporter drives the Sonic Hedgehog pathway contributing to medulloblastoma pathogenesis
Wijaya, Juwina, Vo, BaoHan T, Liu, Jingjing, Xu, Beisi, Wu, Gang, Wang, Yao, Peng, Junmin, Zhang, Jin, Janke, Laura J, Orr, Brent A, Yu, Jiyang, Roussel, Martine F, Schuetz, John D
Published in Cancer research (Chicago, Ill.) (16.01.2020)
Published in Cancer research (Chicago, Ill.) (16.01.2020)
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SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents
Gartrell, Jessica, Mellado-Largarde, Marcia, Clay, Michael R, Bahrami, Armita, Sahr, Natasha A, Sykes, April, Blankenship, Kaley, Hoffmann, Lauren, Xie, Jia, Cho, Hyekyung P, Twarog, Nathaniel, Connelly, Michele, Yan, Koon-Kiu, Yu, Jiyang, Porter, Shaina N, Pruett-Miller, Shondra M, Neale, Geoffrey, Tinkle, Christopher L, Federico, Sara M, Stewart, Elizabeth A, Shelat, Anang A
Published in Molecular cancer therapeutics (01.11.2021)
Published in Molecular cancer therapeutics (01.11.2021)
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Phase IB trial of ACY-1215 (Ricolinostat) combined with nab-paclitaxel in metastatic breast cancer
Kalinsky, Kevin, Onishi, Maika, Yu, JiYang, Trivedi, Meghna S., Accordino, Melissa Kate, Crew, Katherine D., Hershman, Dawn L., Maurer, Matthew A., Silva, Jose
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Abstract 3652: USP7 heterozygous loss-of-function affects T-cell differentiation in pediatric T-ALL
Shaw, Timothy I., Dong, Li, High, Anthony, Liu, Yu, Ju, Bensheng, Kavdia, Kanisha, Pagala, Vishwajeeth, Shaner, Bridget, Easton, John, Qian, Chenxi, Yu, Jiyang, Janke, Janke, Choi, John Kim, Peng, Junmin, Gu, Wei, Downing, James R., Zhang, Jinghui
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract A71: HDAC6 activity is a non-oncogene addiction hub for in inflammatory breast cancers
Putcha, Preeti, Yu, Jiyang, Rodriguez-Barrueco, Ruth, Califano, Andrea, silva, jose
Published in Molecular cancer research (01.02.2016)
Published in Molecular cancer research (01.02.2016)
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Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells
Cheng, Haiying, Zhang, Zhenfeng, Rodriguez-Barrueco, Ruth, Borczuk, Alain, Liu, Huijie, Yu, Jiyang, Silva, Jose M, Cheng, Simon K, Perez-Soler, Roman, Halmos, Balazs
Published in Oncotarget (17.05.2016)
Published in Oncotarget (17.05.2016)
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