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Bai, Yan, Li, Guang, Yung, Laiming, Yu, Paul B, Ai, Xingbin
Published in American journal of physiology. Lung cellular and molecular physiology (01.08.2023)
Published in American journal of physiology. Lung cellular and molecular physiology (01.08.2023)
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The role of bone morphogenetic protein signaling in vascular calcification
Yang, Peiran, Troncone, Luca, Augur, Zachary M., Kim, Stephanie S.J., McNeil, Megan E., Yu, Paul B.
Published in Bone (New York, N.Y.) (01.12.2020)
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A new class of small molecule inhibitor of BMP signaling
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Published in PloS one (30.04.2013)
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A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation
Kim, Jung-Min, Yang, Yeon-Suk, Park, Kwang Hwan, Ge, Xianpeng, Xu, Ren, Li, Na, Song, Minkyung, Chun, Hyunho, Bok, Seoyeon, Charles, Julia F., Filhol-Cochet, Odile, Boldyreff, Brigitte, Dinter, Teresa, Yu, Paul B., Kon, Ning, Gu, Wei, Takarada, Takeshi, Greenblatt, Matthew B., Shim, Jae-Hyuck
Published in Nature communications (08.05.2020)
Published in Nature communications (08.05.2020)
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The traumatic bone: Trauma-induced heterotopic ossification
Dey, Devaveena, Wheatley, Benjamin M, Cholok, David, Agarwal, Shailesh, Yu, Paul B, Levi, Benjamin, Davis, Thomas A
Published in Translational research : the journal of laboratory and clinical medicine (01.08.2017)
Published in Translational research : the journal of laboratory and clinical medicine (01.08.2017)
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Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification
Dey, Devaveena, Bagarova, Jana, Hatsell, Sarah J, Armstrong, Kelli A, Huang, Lily, Ermann, Joerg, Vonner, Ashley J, Shen, Yue, Mohedas, Agustin H, Lee, Arthur, Eekhoff, Elisabeth M W, van Schie, Annelies, Demay, Marie B, Keller, Charles, Wagers, Amy J, Economides, Aris N, Yu, Paul B
Published in Science translational medicine (23.11.2016)
Published in Science translational medicine (23.11.2016)
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Inhibition of Bone Morphogenetic Protein Signaling Reduces Vascular Calcification and Atherosclerosis
Derwall, Matthias, Malhotra, Rajeev, Lai, Carol S, Beppu, Yuko, Aikawa, Elena, Seehra, Jasbir S, Zapol, Warren M, Bloch, Kenneth D, Yu, Paul B
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2012)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2012)
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Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
Yu, Paul B, Hoyng, Stefan A, Bloch, Kenneth D, Lin, Herbert Y, Hong, Charles C, Deng, Donna Y, Peterson, Randall T, Babitt, Jodie L, Sachidanandan, Chetana
Published in Nature chemical biology (01.01.2008)
Published in Nature chemical biology (01.01.2008)
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Bone Morphogenetic Protein 9 Is a Mechanistic Biomarker of Portopulmonary Hypertension
Nikolic, Ivana, Yung, Lai-Ming, Yang, Peiran, Malhotra, Rajeev, Paskin-Flerlage, Samuel D, Dinter, Teresa, Bocobo, Geoffrey A, Tumelty, Kathleen E, Faugno, Anthony J, Troncone, Luca, McNeil, Megan E, Huang, Xiuli, Coser, Kathryn R, Lai, Carol S C, Upton, Paul D, Goumans, Marie Jose, Zamanian, Roham T, Elliott, C Gregory, Lee, Arthur, Zheng, Wei, Berasi, Stephen P, Huard, Christine, Morrell, Nicholas W, Chung, Raymond T, Channick, Richard W, Roberts, Kari E, Yu, Paul B
Published in American journal of respiratory and critical care medicine (01.04.2019)
Published in American journal of respiratory and critical care medicine (01.04.2019)
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Circulating BMP9 Protects the Pulmonary Endothelium during Inflammation-induced Lung Injury in Mice
Li, Wei, Long, Lu, Yang, Xudong, Tong, Zhen, Southwood, Mark, King, Ross, Caruso, Paola, Upton, Paul D, Yang, Peiran, Bocobo, Geoffrey A, Nikolic, Ivana, Higuera, Angelica, Salmon, Richard M, Jiang, He, Lodge, Katharine M, Hoenderdos, Kim, Baron, Rebecca M, Yu, Paul B, Condliffe, Alison M, Summers, Charlotte, Nourshargh, Sussan, Chilvers, Edwin R, Morrell, Nicholas W
Published in American journal of respiratory and critical care medicine (01.06.2021)
Published in American journal of respiratory and critical care medicine (01.06.2021)
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BMP type I receptor inhibition reduces heterotopic ossification
Yu, Paul B, Deng, Donna Y, Lai, Carol S, Hong, Charles C, Cuny, Gregory D, Bouxsein, Mary L, Hong, Deborah W, McManus, Patrick M, Katagiri, Takenobu, Sachidanandan, Chetana, Kamiya, Nobuhiro, Fukuda, Tomokazu, Mishina, Yuji, Peterson, Randall T, Bloch, Kenneth D
Published in Nature medicine (01.12.2008)
Published in Nature medicine (01.12.2008)
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Structure–Activity Relationship of 3,5-Diaryl-2-aminopyridine ALK2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants
Mohedas, Agustin H, Wang, You, Sanvitale, Caroline E, Canning, Peter, Choi, Sungwoon, Xing, Xuechao, Bullock, Alex N, Cuny, Gregory D, Yu, Paul B
Published in Journal of medicinal chemistry (09.10.2014)
Published in Journal of medicinal chemistry (09.10.2014)
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Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension
Joshi, Sachindra R., Liu, Jun, Bloom, Troy, Karaca Atabay, Elif, Kuo, Tzu-Hsing, Lee, Michael, Belcheva, Elitza, Spaits, Matthew, Grenha, Rosa, Maguire, Michelle C., Frost, Jeffrey L., Wang, Kathryn, Briscoe, Steven D., Alexander, Mark J., Herrin, Brantley R., Castonguay, Roselyne, Pearsall, R. Scott, Andre, Patrick, Yu, Paul B., Kumar, Ravindra, Li, Gang
Published in Scientific reports (12.05.2022)
Published in Scientific reports (12.05.2022)
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Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
Aykul, Senem, Huang, Lily, Wang, Lili, Das, Nanditha M, Reisman, Sandra, Ray, Yonaton, Zhang, Qian, Rothman, Nyanza, Nannuru, Kalyan C, Kamat, Vishal, Brydges, Susannah, Troncone, Luca, Johnsen, Laura, Yu, Paul B, Fazio, Sergio, Lees-Shepard, John, Schutz, Kevin, Murphy, Andrew J, Economides, Aris N, Idone, Vincent, Hatsell, Sarah J
Published in The Journal of clinical investigation (15.06.2022)
Published in The Journal of clinical investigation (15.06.2022)
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Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts
Kamiya, Nobuhiro, Kobayashi, Tatsuya, Mochida, Yoshiyuki, Yu, Paul B, Yamauchi, Mitsuo, Kronenberg, Henry M, Mishina, Yuji
Published in Journal of bone and mineral research (01.02.2010)
Published in Journal of bone and mineral research (01.02.2010)
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Development of an ALK2-Biased BMP Type I Receptor Kinase Inhibitor
Mohedas, Agustin H, Xing, Xuechao, Armstrong, Kelli A, Bullock, Alex N, Cuny, Gregory D, Yu, Paul B
Published in ACS chemical biology (21.06.2013)
Published in ACS chemical biology (21.06.2013)
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Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells
Hao, Jijun, Daleo, Marie A, Murphy, Clare K, Yu, Paul B, Ho, Joshua N, Hu, Jianyong, Peterson, Randall T, Hatzopoulos, Antonis K, Hong, Charles C
Published in PloS one (06.08.2008)
Published in PloS one (06.08.2008)
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Diminished muscle integrity in patients with fibrodysplasia ossificans progressiva assessed with at-home electrical impedance myography
Farid, Alexander, Golden, Emma, Robicheau, Sara, Hu, Alice, Cheung, Kin, Yu, Paul B., Rutkove, Seward B., Upadhyay, Jaymin
Published in Scientific reports (03.12.2022)
Published in Scientific reports (03.12.2022)
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Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors
Cuny, Gregory D., Yu, Paul B., Laha, Joydev K., Xing, Xuechao, Liu, Ji-Feng, Lai, Carol S., Deng, Donna Y., Sachidanandan, Chetana, Bloch, Kenneth D., Peterson, Randall T.
Published in Bioorganic & medicinal chemistry (01.08.2008)
Published in Bioorganic & medicinal chemistry (01.08.2008)
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