Targeting Peroxisome Proliferator-Activated Receptors (PPARs): Development of Modulators
Pirat, Céline, Farce, Amaury, Lebègue, Nicolas, Renault, Nicolas, Furman, Christophe, Millet, Régis, Yous, Saı̈d, Speca, Silvia, Berthelot, Pascal, Desreumaux, Pierre, Chavatte, Philippe
Published in Journal of medicinal chemistry (10.05.2012)
Published in Journal of medicinal chemistry (10.05.2012)
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Journal Article
Structural basis of ligand recognition at the human MT1 melatonin receptor
Stauch, Benjamin, Johansson, Linda C., McCorvy, John D., Patel, Nilkanth, Han, Gye Won, Huang, Xi-Ping, Gati, Cornelius, Batyuk, Alexander, Slocum, Samuel T., Ishchenko, Andrii, Brehm, Wolfgang, White, Thomas A., Michaelian, Nairie, Madsen, Caleb, Zhu, Lan, Grant, Thomas D., Grandner, Jessica M., Shiriaeva, Anna, Olsen, Reid H. J., Tribo, Alexandra R., Yous, Saïd, Stevens, Raymond C., Weierstall, Uwe, Katritch, Vsevolod, Roth, Bryan L., Liu, Wei, Cherezov, Vadim
Published in Nature (London) (09.05.2019)
Published in Nature (London) (09.05.2019)
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Journal Article
XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity
Johansson, Linda C., Stauch, Benjamin, McCorvy, John D., Han, Gye Won, Patel, Nilkanth, Huang, Xi-Ping, Batyuk, Alexander, Gati, Cornelius, Slocum, Samuel T., Li, Chufeng, Grandner, Jessica M., Hao, Shuming, Olsen, Reid H. J., Tribo, Alexandra R., Zaare, Sahba, Zhu, Lan, Zatsepin, Nadia A., Weierstall, Uwe, Yous, Saïd, Stevens, Raymond C., Liu, Wei, Roth, Bryan L., Katritch, Vsevolod, Cherezov, Vadim
Published in Nature (London) (24.04.2019)
Published in Nature (London) (24.04.2019)
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Journal Article
Melatonin facts: Lack of evidence that melatonin is a radical scavenger in living systems
Boutin, Jean A., Liberelle, Maxime, Yous, Saïd, Ferry, Gilles, Nepveu, Françoise
Published in Journal of pineal research (01.01.2024)
Published in Journal of pineal research (01.01.2024)
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Journal Article
Novel Quinazoline Derivatives as Highly Effective A2A Adenosine Receptor Antagonists
Laversin, Amélie, Dufossez, Robin, Bolteau, Raphaël, Duroux, Romain, Ravez, Séverine, Hernandez-Tapia, Sergio, Fossart, Martin, Coevoet, Mathilde, Liberelle, Maxime, Yous, Saïd, Lebègue, Nicolas, Melnyk, Patricia
Published in Molecules (Basel, Switzerland) (14.08.2024)
Published in Molecules (Basel, Switzerland) (14.08.2024)
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Journal Article
High ligand efficiency quinazoline compounds as novel A2A adenosine receptor antagonists
Bolteau, Raphaël, Duroux, Romain, Laversin, Amélie, Vreulz, Brandon, Shiriaeva, Anna, Stauch, Benjamin, Han, Gye Won, Cherezov, Vadim, Renault, Nicolas, Barczyk, Amélie, Ravez, Séverine, Coevoet, Mathilde, Melnyk, Patricia, Liberelle, Maxime, Yous, Saïd
Published in European journal of medicinal chemistry (05.11.2022)
Published in European journal of medicinal chemistry (05.11.2022)
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Journal Article
Quinazoline and phthalazine derivatives as novel melatonin receptor ligands analogues of agomelatine
Bolteau, Raphaël, Descamps, Florian, Ettaoussi, Mohamed, Caignard, Daniel H., Delagrange, Philippe, Melnyk, Patricia, Yous, Saïd
Published in European journal of medicinal chemistry (01.03.2020)
Published in European journal of medicinal chemistry (01.03.2020)
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Journal Article
A putative new melatonin binding site in sheep brain, MTx: preliminary observations and characteristics
Shabajee-Alibay, Preety, Bonnaud, Anne, Malpaux, Benoit, Delagrange, Philippe, Audinot, Valérie, Yous, Said, Boutin, Jean A, Stephan, Jean-Philippe, Leprince, Jérôme, Legros, Celine
Published in The Journal of pharmacology and experimental therapeutics (01.01.2022)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2022)
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Journal Article
Synthesis and biological evaluation of new naphtho- and quinolinocyclopentane derivatives as potent melatoninergic (MT1/MT2) and serotoninergic (5-HT2C) dual ligands
Duroux, Romain, Rami, Marouan, Landagaray, Elodie, Ettaoussi, Mohamed, Caignard, Daniel-Henri, Delagrange, Philippe, Melnyk, Patricia, Yous, Saïd
Published in European journal of medicinal chemistry (01.12.2017)
Published in European journal of medicinal chemistry (01.12.2017)
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Journal Article
Radiosynthesis and In Vivo Evaluation of Four Positron Emission Tomography Tracer Candidates for Imaging of Melatonin Receptors
Bdair, Hussein, Singleton, Thomas A, Ross, Karen, Jolly, Dean, Kang, Min Su, Aliaga, Arturo, Tuznik, Marius, Kaur, Tanpreet, Yous, Saïd, Soucy, Jean-Paul, Massarweh, Gassan, Scott, Peter J. H, Koeppe, Robert, Spadoni, Gilberto, Bedini, Annalida, Rudko, David A, Gobbi, Gabriella, Benkelfat, Chawki, Rosa-Neto, Pedro, Brooks, Allen F, Kostikov, Alexey
Published in ACS chemical neuroscience (04.05.2022)
Published in ACS chemical neuroscience (04.05.2022)
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Journal Article
Synthesis and SAR Studies of Isoquinoline and Tetrahydroisoquinoline Derivatives as Melatonin Receptor Ligands
Ettaoussi, Mohamed, Laversin, Amélie, Vreulz, Brandon, Rami, Marouane, Lebegue, Nicolas, Delagrange, Philippe, Caignard, Daniel Henri, Melnyk, Patricia, Liberelle, Maxime, Yous, Saïd
Published in ChemMedChem (04.02.2022)
Published in ChemMedChem (04.02.2022)
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Journal Article
Rexinoid Bexarotene Modulates Triglyceride but not Cholesterol Metabolism via Gene-Specific Permissivity of the RXR/LXR Heterodimer in the Liver
Lalloyer, Fanny, Pedersen, Thomas Åskov, Gross, Barbara, Lestavel, Sophie, Yous, Saïd, Vallez, Emmanuelle, Gustafsson, Jan-Åke, Mandrup, Susanne, Fiévet, Catherine, Staels, Bart, Tailleux, Anne
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2009)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2009)
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Journal Article
Design and synthesis of 2,6-disubstituted-8-amino imidazo[1,2a]pyridines, a promising privileged structure
Boulahjar, Rajaa, Rincon Arias, Angela, Bolteau, Raphaël, Renault, Nicolas, Coevoet, Mathilde, Barczyk, Amélie, Duroux, Romain, Yous, Saïd, Melnyk, Patricia, Agouridas, Laurence
Published in Bioorganic & medicinal chemistry (23.07.2018)
Published in Bioorganic & medicinal chemistry (23.07.2018)
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Journal Article
Enantioseparation and thermodynamic study of naphthalene derivatives, new melatoninergic agonists, on coated amylose [tris(S)-1-phenylethylcarbamate] stationary phase. Transposition to preparative scale
Landagaray, Elodie, Yous, Saïd, Vaccher, Claude, Lipka, Emmanuelle
Published in Biomedical chromatography (01.05.2015)
Published in Biomedical chromatography (01.05.2015)
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Journal Article
New quinolinic derivatives as melatonergic ligands: Synthesis and pharmacological evaluation
Landagaray, Elodie, Ettaoussi, Mohamed, Rami, Marouan, Boutin, Jean A., Caignard, Daniel-Henri, Delagrange, Philippe, Melnyk, Patricia, Berthelot, Pascal, Yous, Saïd
Published in European journal of medicinal chemistry (15.02.2017)
Published in European journal of medicinal chemistry (15.02.2017)
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Journal Article
The RXR Agonist Bexarotene Improves Cholesterol Homeostasis and Inhibits Atherosclerosis Progression in a Mouse Model of Mixed Dyslipidemia
Lalloyer, Fanny, Fiévet, Catherine, Lestavel, Sophie, Torpier, Gérard, van der Veen, Jelske, Touche, Véronique, Bultel, Stéphanie, Yous, Saïd, Kuipers, Folkert, Paumelle, Réjane, Fruchart, Jean-Charles, Staels, Bart, Tailleux, Anne
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2006)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2006)
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