Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
Miller, Edward J, Li, Ji, Leng, Lin, McDonald, Courtney, Atsumi, Toshiya, Bucala, Richard, Young, Lawrence H
Published in Nature (31.01.2008)
Published in Nature (31.01.2008)
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PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia
Ola, Roxana, Dubrac, Alexandre, Han, Jinah, Zhang, Feng, Fang, Jennifer S, Larrivée, Bruno, Lee, Monica, Urarte, Ana A, Kraehling, Jan R, Genet, Gael, Hirschi, Karen K, Sessa, William C, Canals, Francesc V, Graupera, Mariona, Yan, Minhong, Young, Lawrence H, Oh, Paul S, Eichmann, Anne
Published in Nature communications (29.11.2016)
Published in Nature communications (29.11.2016)
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AMP-Activated Protein Kinase Regulates the Assembly of Epithelial Tight Junctions
Zhang, Li, Li, Ji, Young, Lawrence H., Caplan, Michael J.
Published in Proceedings of the National Academy of Sciences - PNAS (14.11.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (14.11.2006)
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Journal Article
Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion
Qi, Dake, Hu, Xiaoyue, Wu, Xiaohong, Merk, Melanie, Leng, Lin, Bucala, Richard, Young, Lawrence H
Published in The Journal of clinical investigation (01.12.2009)
Published in The Journal of clinical investigation (01.12.2009)
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Angiotensin Receptor Neprilysin Inhibitor Attenuates Myocardial Remodeling and Improves Infarct Perfusion in Experimental Heart Failure
Pfau, Daniel, Thorn, Stephanie L, Zhang, Jiasheng, Mikush, Nicole, Renaud, Jennifer M, Klein, Ran, deKemp, Robert A, Wu, Xiaohong, Hu, Xiaoyue, Sinusas, Albert J, Young, Lawrence H, Tirziu, Daniela
Published in Scientific reports (08.04.2019)
Published in Scientific reports (08.04.2019)
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Mitochondrial network remodeling of the diabetic heart: implications to ischemia related cardiac dysfunction
Rudokas, Michael W., McKay, Margaret, Toksoy, Zeren, Eisen, Julia N., Bögner, Markus, Young, Lawrence H., Akar, Fadi G.
Published in Cardiovascular diabetology (18.07.2024)
Published in Cardiovascular diabetology (18.07.2024)
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Aging-Associated Reductions in AMP-Activated Protein Kinase Activity and Mitochondrial Biogenesis
Reznick, Richard M., Zong, Haihong, Li, Ji, Morino, Katsutaro, Moore, Irene K., Yu, Hannah J., Liu, Zhen-Xiang, Dong, Jianying, Mustard, Kirsty J., Hawley, Simon A., Befroy, Douglas, Pypaert, Marc, Hardie, D. Grahame, Young, Lawrence H., Shulman, Gerald I.
Published in Cell metabolism (01.02.2007)
Published in Cell metabolism (01.02.2007)
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Journal Article
AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia
Zaha, Vlad G, Qi, Dake, Su, Kevin N, Palmeri, Monica, Lee, Hui-Young, Hu, Xiaoyue, Wu, Xiaohong, Shulman, Gerald I, Rabinovitch, Peter S, Russell, Raymond R, Young, Lawrence H
Published in Journal of molecular and cellular cardiology (01.02.2016)
Published in Journal of molecular and cellular cardiology (01.02.2016)
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Journal Article
Screening for Coronary Artery Disease in Patients With Diabetes
Bax, Jeroen J, Young, Lawrence H, Frye, Robert L, Bonow, Robert O, Steinberg, Helmut O, Barrett, Eugene J
Published in Diabetes care (01.10.2007)
Published in Diabetes care (01.10.2007)
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Journal Article
Conference Proceeding
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
Russell, 3rd, Raymond R, Li, Ji, Coven, David L, Pypaert, Marc, Zechner, Christoph, Palmeri, Monica, Giordano, Frank J, Mu, James, Birnbaum, Morris J, Young, Lawrence H
Published in The Journal of clinical investigation (01.08.2004)
Published in The Journal of clinical investigation (01.08.2004)
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Journal Article
Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesity
Chen, Liujun, Li, Lisha, Cui, Donghong, Huang, Yiheng, Tong, Haibin, Zabihi, Haleh, Wang, Shuxia, Qi, Yadan, Lakowski, Ted, Leng, Lin, Liu, Suixin, Wu, Hong, Young, Lawrence H, Bucala, Richard, Qi, Dake
Published in Molecular metabolism (Germany) (01.01.2024)
Published in Molecular metabolism (Germany) (01.01.2024)
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Journal Article
AMP Kinase Is Required for Mitochondrial Biogenesis in Skeletal Muscle in Response to Chronic Energy Deprivation
Zong, Haihong, Ren, Jian Ming, Young, Lawrence H., Pypaert, Marc, Mu, James, Birnbaum, Morris J., Shulman, Gerald I.
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2002)
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Journal Article
AMPK and the Atrial Response to Metabolic Inhibition
Kim, Grace E., PhD, Young, Lawrence H., MD
Published in Journal of the American College of Cardiology (07.07.2015)
Published in Journal of the American College of Cardiology (07.07.2015)
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Journal Article
AMP-Activated Protein Kinase Activates p38 Mitogen-Activated Protein Kinase by Increasing Recruitment of p38 MAPK to TAB1 in the Ischemic Heart
Li, Ji, Miller, Edward J, Ninomiya-Tsuji, Jun, Russell, Raymond R, Young, Lawrence H
Published in Circulation research (28.10.2005)
Published in Circulation research (28.10.2005)
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An explainable machine learning-based phenomapping strategy for adaptive predictive enrichment in randomized clinical trials
Oikonomou, Evangelos K, Thangaraj, Phyllis M, Bhatt, Deepak L, Ross, Joseph S, Young, Lawrence H, Krumholz, Harlan M, Suchard, Marc A, Khera, Rohan
Published in NPJ digital medicine (25.11.2023)
Published in NPJ digital medicine (25.11.2023)
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Journal Article
Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart
Ji Li, Qi, Dake, Cheng, Haiying, Hu, Xiaoyue, Miller, Edward J., Wu, Xiaohong, Russell, Kerry S., Mikush, Nicole, Zhang, Jiasheng, Lei Xiao, Sherwin, Robert S., Young, Lawrence H.
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.2013)
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Journal Article
Diabetes Exacerbates Myocardial Ischemia/Reperfusion Injury by Down-Regulation of MicroRNA and Up-Regulation of O-GlcNAcylation
Wang, Dandan, Hu, Xiaoyue, MD, Lee, Seung Hee, PhD, Chen, Feng, BS, Jiang, Kai, BS, Tu, Zizhuo, BS, Liu, Zejian, PhD, Du, Jing, MD, PhD, Wang, Li, PhD, Yin, Chaoying, PhD, Liao, Yu, MD, Shang, Hongcai, PhD, Martin, Kathleen A., PhD, Herzog, Raimund I., MD, Young, Lawrence H., MD, Qian, Li, PhD, Hwa, John, MD, PhD, Xiang, Yaozu, MD, PhD
Published in JACC. Basic to translational science (01.06.2018)
Published in JACC. Basic to translational science (01.06.2018)
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Pioglitazone for secondary prevention after ischemic stroke and transient ischemic attack: Rationale and design of the Insulin Resistance Intervention after Stroke Trial
Viscoli, Catherine M., PhD, Brass, Lawrence M., MD, Carolei, Antonio, MD, Conwit, Robin, MD, Ford, Gary A., FRCP, Furie, Karen L., MD, MPH, Gorman, Mark, MD, Guarino, Peter D., PhD, Inzucchi, Silvio E., MD, Lovejoy, Anne M., PA-C, Parsons, Mark W., MD, Peduzzi, Peter N., PhD, Ringleb, Peter A., MD, Schwartz, Gregory G., MD, PhD, Spence, J. David, MD, Tanne, David, MD, Young, Lawrence H., MD, Kernan, Walter N., MD
Published in The American heart journal (01.12.2014)
Published in The American heart journal (01.12.2014)
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Journal Article
Resolution of Asymptomatic Myocardial Ischemia in Patients With Type 2 Diabetes in the Detection of Ischemia in Asymptomatic Diabetics (DIAD) Study
Wackers, Frans J. Th, Chyun, Deborah A, Young, Lawrence H, Heller, Gary V, Iskandrian, Ami E, Davey, Janice A, Barrett, Eugene J, Taillefer, Raymond, Wittlin, Steven D, Filipchuk, Neil, Ratner, Robert E, Inzucchi, Silvio E
Published in Diabetes care (01.11.2007)
Published in Diabetes care (01.11.2007)
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