Molecular Mechanism of Hepatitis C Virus Replicon Variants with Reduced Susceptibility to a Benzofuran Inhibitor, HCV-796
Howe, Anita Y M, Cheng, Huiming, Johann, Stephen, Mullen, Stanley, Chunduru, Srinivas K, Young, Dorothy C, Bard, Joel, Chopra, Rajiv, Krishnamurthy, Girija, Mansour, Tarek, O'Connell, John
Published in Antimicrobial Agents and Chemotherapy (01.09.2008)
Published in Antimicrobial Agents and Chemotherapy (01.09.2008)
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structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation
Choi, K.H, Groarke, J.M, Young, D.C, Kuhn, R.J, Smith, J.L, Pevear, D.C, Rossmann, M.G
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2004)
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The Discovery of Pyrano[3,4-b]indole-Based Allosteric Inhibitors of HCV NS5B Polymerase with In Vivo Activity
LaPorte, Matthew G., Jackson, Randy W., Draper, Tandy L., Gaboury, Janet A., Galie, Kristin, Herbertz, Torsten, Hussey, Alison R., Rippin, Susan R., Benetatos, Christopher A., Chunduru, Srinivas K., Christensen, Joel S., Coburn, Glen A., Rizzo, Christopher J., Rhodes, Gerry, O'Connell, John, Howe, Anita Y. M., Mansour, Tarek S., Collett, Marc S., Pevear, Daniel C., Young, Dorothy C., Gao, Tiejun, Tyrrell , D. Lorne J., Kneteman, Norman M., Burns, Christopher J., Condon, Stephen M.
Published in ChemMedChem (20.10.2008)
Published in ChemMedChem (20.10.2008)
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Newly Synthesized Hepatitis C Virus Replicon RNA Is Protected from Nuclease Activity by a Protease-Sensitive Factor(s)
GUANG YANG, PEVEAR, Daniel C, COLLETT, Marc S, CHUNDURU, Srinivas, YOUNG, Dorothy C, BENETATOS, Christopher, JORDAN, Robert
Published in Journal of Virology (01.09.2004)
Published in Journal of Virology (01.09.2004)
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The discovery and structure–activity relationships of pyrano[3,4- b]indole-based inhibitors of hepatitis C virus NS5B polymerase
Jackson, Randy W., LaPorte, Matthew G., Herbertz, Torsten, Draper, Tandy L., Gaboury, Janet A., Rippin, Susan R., Patel, Ravi, Chunduru, Srinivas K., Benetatos, Christopher A., Young, Dorothy C., Burns, Christopher J., Condon, Stephen M.
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
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The discovery and structure–activity relationships of pyrano[3,4- b]indole based inhibitors of hepatitis C virus NS5B polymerase
LaPorte, Matthew G., Draper, Tandy L., Miller, Lori E., Blackledge, Charles W., Leister, Lara K., Amparo, Eugene, Hussey, Alison R., Young, Dorothy C., Chunduru, Srinivas K., Benetatos, Christopher A., Rhodes, Gerry, Gopalsamy, Ariamala, Herbertz, Torsten, Burns, Christopher J., Condon, Stephen M.
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
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Novel Nonnucleoside Inhibitor of Hepatitis C Virus RNA-Dependent RNA Polymerase
HOWE, Anita Y. M, BLOOM, Johnathan, GORCZYCA, William P, HERRRNANN, Steve, JOHANN, Stephen, XIAOQUN JIANG, KIMBERLAND, Michelle L, KRISNAMURTHY, Girija, OLSON, Matthew, ORLOWSKI, Mark, SWANBERG, Steve, THOMPSON, Ian, BALDICK, Carl J, THORN, Megan, DEL VECCHIO, Alfred, YOUNG, Dorothy C, VAN ZEIJL, Marja, ELLINGBOE, John W, UPESLACIS, Janis, COLLETT, Marc, MANSOUR, Tarek S, O'CONNELL, John F, BENETATOS, Christopher A, HUIMING CHENG, CHRISTENSEN, Joel S, CHUNDURU, Srinivas K, COBURN, Glen A, FELD, Boris, GOPALSAMY, Ariamala
Published in Antimicrobial Agents and Chemotherapy (01.12.2004)
Published in Antimicrobial Agents and Chemotherapy (01.12.2004)
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Design, expression, and purification of a Flaviviridae polymerase using a high‐throughput approach to facilitate crystal structure determination
Choi, Kyung H., Groarke, James M., Young, Dorothy C., Rossmann, Michael G., Pevear, Daniel C., Kuhn, Richard J., Smith, Janet L.
Published in Protein science (01.10.2004)
Published in Protein science (01.10.2004)
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Wentland, Mark P, Perni, Robert B, Dorff, Peter H, Brundage, R. Pauline, Castaldi, Michael J, Bailey, Thomas R, Carabateas, Philip M, Bacon, Edward R, Young, Dorothy C
Published in Journal of medicinal chemistry (28.05.1993)
Published in Journal of medicinal chemistry (28.05.1993)
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Keto/Enol Epoxy Steroids as HIV-1 Tat Inhibitors: Structure-Activity Relationships and Pharmacophore Localization
Michne, William F, Schroeder, Joseph D, Bailey, Thomas R, Neumann, Helmut C, Cooke, Debra, Young, Dorothy C, Hughes, Joseph V, Kingsley, Susan D, Ryan, Kathryn A, Putz, Henry S, Shaw, Lucinda J, Dutko, Frank J
Published in Journal of medicinal chemistry (01.08.1995)
Published in Journal of medicinal chemistry (01.08.1995)
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Keto/enol epoxy steroids: a new structural class of HIV-1 tat inhibitors
Michne, William F, Schroeder, Joseph D, Bailey, Thomas R, Young, Dorothy C, Hughes, Joseph V, Dutko, Frank J
Published in Journal of medicinal chemistry (03.09.1993)
Published in Journal of medicinal chemistry (03.09.1993)
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Cyclic Variations of 3-Quinolinecarboxamides and Effects on Antiherpetic Activity
Wentland, Mark P, Carlson, John A, Dorff, Peter H, Aldous, Suzanne C, Perni, Robert B, Young, Dorothy C, Woods, Maureen G, Kingsley, Susan D, Ryan, Kathryn A, Rosi, David, Drozd, Marion L, Dutko, Frank J
Published in Journal of medicinal chemistry (01.07.1995)
Published in Journal of medicinal chemistry (01.07.1995)
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