Predicting and Preventing Immune Checkpoint Inhibitor Toxicity: Targeting Cytokines
Kang, Jee Hye, Bluestone, Jeffrey A., Young, Arabella
Published in Trends in immunology (01.04.2021)
Published in Trends in immunology (01.04.2021)
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Journal Article
The Balancing Act between Cancer Immunity and Autoimmunity in Response to Immunotherapy
Young, Arabella, Quandt, Zoe, Bluestone, Jeffrey A
Published in Cancer immunology research (01.12.2018)
Published in Cancer immunology research (01.12.2018)
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Journal Article
Targeting cancer-derived adenosine: new therapeutic approaches
Young, Arabella, Mittal, Deepak, Stagg, John, Smyth, Mark J
Published in Cancer discovery (01.08.2014)
Published in Cancer discovery (01.08.2014)
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Journal Article
Improved Efficacy of Neoadjuvant Compared to Adjuvant Immunotherapy to Eradicate Metastatic Disease
Liu, Jing, Blake, Stephen J, Yong, Michelle C R, Harjunpää, Heidi, Ngiow, Shin Foong, Takeda, Kazuyoshi, Young, Arabella, O'Donnell, Jake S, Allen, Stacey, Smyth, Mark J, Teng, Michele W L
Published in Cancer discovery (01.12.2016)
Published in Cancer discovery (01.12.2016)
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Journal Article
Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity
Wang, David, Quiros, Jason, Mahuron, Kelly, Pai, Chien-Chun, Ranzani, Valeria, Young, Arabella, Silveria, Stephanie, Harwin, Tory, Abnousian, Arbi, Pagani, Massimiliano, Rosenblum, Michael D., Van Gool, Frederic, Fong, Lawrence, Bluestone, Jeffrey A., DuPage, Michel
Published in Cell reports (Cambridge) (12.06.2018)
Published in Cell reports (Cambridge) (12.06.2018)
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Journal Article
Co-inhibition of CD73 and A2AR Adenosine Signaling Improves Anti-tumor Immune Responses
Young, Arabella, Ngiow, Shin Foong, Barkauskas, Deborah S., Sult, Erin, Hay, Carl, Blake, Stephen J., Huang, Qihui, Liu, Jing, Takeda, Kazuyoshi, Teng, Michele W.L., Sachsenmeier, Kris, Smyth, Mark J.
Published in Cancer cell (12.09.2016)
Published in Cancer cell (12.09.2016)
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Journal Article
A2AR Adenosine Signaling Suppresses Natural Killer Cell Maturation in the Tumor Microenvironment
Young, Arabella, Ngiow, Shin Foong, Gao, Yulong, Patch, Ann-Marie, Barkauskas, Deborah S, Messaoudene, Meriem, Lin, Gene, Coudert, Jerome D, Stannard, Kimberley A, Zitvogel, Laurence, Degli-Esposti, Mariapia A, Vivier, Eric, Waddell, Nicola, Linden, Joel, Huntington, Nicholas D, Souza-Fonseca-Guimaraes, Fernando, Smyth, Mark J
Published in Cancer research (Chicago, Ill.) (15.02.2018)
Published in Cancer research (Chicago, Ill.) (15.02.2018)
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Journal Article
Antimetastatic Effects of Blocking PD-1 and the Adenosine A2A Receptor
MITTAL, Deepak, YOUNG, Arabella, STANNARD, Kimberley, YONG, Michelle, TENG, Michele W. L, ALLARD, Bertrand, STAGG, John, SMYTH, Mark J
Published in Cancer research (Chicago, Ill.) (15.07.2014)
Published in Cancer research (Chicago, Ill.) (15.07.2014)
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Journal Article
Adenosine 2B Receptor Expression on Cancer Cells Promotes Metastasis
Mittal, Deepak, Sinha, Debottam, Barkauskas, Deborah, Young, Arabella, Kalimutho, Murugan, Stannard, Kimberley, Caramia, Franco, Haibe-Kains, Benjamin, Stagg, John, Khanna, Kum Kum, Loi, Sherene, Smyth, Mark J
Published in Cancer research (Chicago, Ill.) (01.08.2016)
Published in Cancer research (Chicago, Ill.) (01.08.2016)
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Journal Article
G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis
Casciello, Francesco, Al-Ejeh, Fares, Kelly, Greg, Brennan, Donal J., Ngiow, Shin Foong, Young, Arabella, Stoll, Thomas, Windloch, Karolina, Hill, Michelle M., Smyth, Mark J., Gannon, Frank, Lee, Jason S.
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2017)
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Journal Article
MAPK Signaling and Inflammation Link Melanoma Phenotype Switching to Induction of CD73 during Immunotherapy
Reinhardt, Julia, Landsberg, Jennifer, Schmid-Burgk, Jonathan L, Ramis, Bartomeu Bibiloni, Bald, Tobias, Glodde, Nicole, Lopez-Ramos, Dorys, Young, Arabella, Ngiow, Shin Foong, Nettersheim, Daniel, Schorle, Hubert, Quast, Thomas, Kolanus, Waldemar, Schadendorf, Dirk, Long, Georgina V, Madore, Jason, Scolyer, Richard A, Ribas, Antoni, Smyth, Mark J, Tumeh, Paul C, Tüting, Thomas, Hölzel, Michael
Published in Cancer research (Chicago, Ill.) (01.09.2017)
Published in Cancer research (Chicago, Ill.) (01.09.2017)
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Journal Article
NK cells require IL-28R for optimal in vivo activity
Souza-Fonseca-Guimaraes, Fernando, Young, Arabella, Mittal, Deepak, Martinet, Ludovic, Bruedigam, Claudia, Takeda, Kazuyoshi, Andoniou, Christopher E., Degli-Esposti, Mariapia A., Hill, Geoffrey R., Smyth, Mark J.
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2015)
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Journal Article
Analysing the types of evidence used by Australian federal parliamentary committees
Ray, Andrew, Young, Arabella, Grant, Will J.
Published in Australian journal of public administration (01.06.2022)
Published in Australian journal of public administration (01.06.2022)
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Journal Article
DNA methylation changes following DNA damage in prostate cancer cells
Sutton, Laura P., Jeffreys, Sarah A., Phillips, Jessica L., Taberlay, Phillippa C., Holloway, Adele F., Ambrose, Mark, Joo, Ji-Hoon E., Young, Arabella, Berry, Rachael, Skala, Marketa, Brettingham-Moore, Kate H.
Published in Epigenetics (03.10.2019)
Published in Epigenetics (03.10.2019)
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Journal Article
1238 Risk evaluation of immune checkpoint inhibitor diabetes through islet autoantibodies & HLA types in a large, real-world cohort
Quandt, Zoe, Liang, Samantha, Lucas, Anastasia, Thompson, Marshall, Saha, Ashis, Hammer, Christian, Herold, Kevan, Young, Arabella, Spencer, Christine, Anderson, Mark
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Immune cells and their inflammatory mediators modify β cells and cause checkpoint inhibitor-induced diabetes
Perdigoto, Ana Luisa, Deng, Songyan, Du, Katherine C, Kuchroo, Manik, Burkhardt, Daniel B, Tong, Alexander, Israel, Gary, Robert, Marie E, Weisberg, Stuart P, Kirkiles-Smith, Nancy, Stamatouli, Angeliki M, Kluger, Harriet M, Quandt, Zoe, Young, Arabella, Yang, Mei-Ling, Mamula, Mark J, Pober, Jordan S, Anderson, Mark S, Krishnaswamy, Smita, Herold, Kevan C
Published in JCI insight (08.09.2022)
Published in JCI insight (08.09.2022)
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Journal Article
1270 Predicting risk factors for severe immune-related adverse events requiring hospitalization from checkpoint inhibitors
Silverstein, Jordyn, Wang, Michelle, Wright, Francis, Huang, Joy, Santhakumar, Jessica, Duvalyan, Eva, Young, Arabella, Kim, Daniel, Dios, Kimberly De, Brondfield, Sam, Quandt, Zoe
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
RNA-seq profiling of a radiation resistant and radiation sensitive prostate cancer cell line highlights opposing regulation of DNA repair and targets for radiosensitization
Young, Arabella, Berry, Rachael, Holloway, Adele F, Blackburn, Nicholas B, Dickinson, Joanne L, Skala, Marketa, Phillips, Jessica L, Brettingham-Moore, Kate H
Published in BMC cancer (04.11.2014)
Published in BMC cancer (04.11.2014)
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Journal Article
Spectrum of Clinical Presentations, Imaging Findings, and HLA Types in Immune Checkpoint Inhibitor–Induced Hypophysitis
Quandt, Zoe, Kim, Stephanie, Villanueva-Meyer, Javier, Coupe, Catherine, Young, Arabella, Kang, Jee Hye, Yazdany, Jinoos, Schmajuk, Gabriela, Rush, Stephanie, Ziv, Elad, Perdigoto, Ana Luisa, Herold, Kevan, Lechner, Melissa G, Su, Maureen A, Tyrrell, J Blake, Bluestone, Jeffrey, Anderson, Mark, Masharani, Umesh
Published in Journal of the Endocrine Society (09.02.2023)
Published in Journal of the Endocrine Society (09.02.2023)
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Journal Article