Characterization of CD90/Thy-1 as a crucial molecular signature for myogenic differentiation in human urine-derived cells through single-cell RNA sequencing
Kunitake, Katsuhiko, Motohashi, Norio, Inoue, Takafumi, Suzuki, Yutaka, Aoki, Yoshitsugu
Published in Scientific reports (28.01.2024)
Published in Scientific reports (28.01.2024)
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The R436Q missense mutation in WWP1 disrupts autoinhibition of its E3 ubiquitin ligase activity, leading to self-degradation and loss of function
Imamura, Michihiro, Matsumoto, Hirokazu, Mannen, Hideyuki, Takeda, Shin’ichi, Aoki, Yoshitsugu
Published in In vitro cellular & developmental biology. Animal (01.08.2024)
Published in In vitro cellular & developmental biology. Animal (01.08.2024)
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Pharmacological activation of SERCA ameliorates dystrophic phenotypes in dystrophin-deficient mdx mice
Nogami, Ken'ichiro, Maruyama, Yusuke, Sakai-Takemura, Fusako, Motohashi, Norio, Elhussieny, Ahmed, Imamura, Michihiro, Miyashita, Satoshi, Ogawa, Megumu, Noguchi, Satoru, Tamura, Yuki, Kira, Jun-ichi, Aoki, Yoshitsugu, Takeda, Shin'ichi, Miyagoe-Suzuki, Yuko
Published in Human molecular genetics (31.05.2021)
Published in Human molecular genetics (31.05.2021)
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Identification of muscle-specific microRNAs in serum of muscular dystrophy animal models: promising novel blood-based markers for muscular dystrophy
Mizuno, Hideya, Nakamura, Akinori, Aoki, Yoshitsugu, Ito, Naoki, Kishi, Soichiro, Yamamoto, Kazuhiro, Sekiguchi, Masayuki, Takeda, Shin'ichi, Hashido, Kazuo
Published in PloS one (30.03.2011)
Published in PloS one (30.03.2011)
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Dissociation of SH3 and cysteine-rich domain 3 and junctophilin 1 from dihydropyridine receptor in dystrophin-deficient muscles
Ashida, Yuki, Himori, Koichi, Tokuda, Nao, Naito, Azuma, Yamauchi, Nao, Takenaka-Ninagawa, Nana, Aoki, Yoshitsugu, Sakurai, Hidetoshi, Yamada, Takashi
Published in American Journal of Physiology: Cell Physiology (01.09.2022)
Published in American Journal of Physiology: Cell Physiology (01.09.2022)
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C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia
Aoki, Yoshitsugu, Manzano, Raquel, Lee, Yi, Dafinca, Ruxandra, Aoki, Misako, Douglas, Andrew G L, Varela, Miguel A, Sathyaprakash, Chaitra, Scaber, Jakub, Barbagallo, Paola, Vader, Pieter, Mäger, Imre, Ezzat, Kariem, Turner, Martin R, Ito, Naoki, Gasco, Samanta, Ohbayashi, Norihiko, El Andaloussi, Samir, Takeda, Shin'ichi, Fukuda, Mitsunori, Talbot, Kevin, Wood, Matthew J A
Published in Brain (London, England : 1878) (01.04.2017)
Published in Brain (London, England : 1878) (01.04.2017)
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Resolution of fibrosis in mdx dystrophic mouse after oral consumption of N-163 strain of Aureobasidium pullulans produced β-glucan
Preethy, Senthilkumar, Aoki, Yoshitsugu, Minegishi, Katsura, Iwasaki, Masaru, Senthilkumar, Rajappa, Abraham, Samuel J. K.
Published in Scientific reports (09.10.2023)
Published in Scientific reports (09.10.2023)
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Deletion of exons 3-9 encompassing a mutational hot spot in the DMD gene presents an asymptomatic phenotype, indicating a target region for multiexon skipping therapy
Nakamura, Akinori, Fueki, Noboru, Shiba, Naoko, Motoki, Hirohiko, Miyazaki, Daigo, Nishizawa, Hitomi, Echigoya, Yusuke, Yokota, Toshifumi, Aoki, Yoshitsugu, Takeda, Shin'ichi
Published in Journal of human genetics (01.07.2016)
Published in Journal of human genetics (01.07.2016)
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In-frame Dystrophin Following Exon 51-Skipping Improves Muscle Pathology and Function in the Exon 52–Deficient mdx Mouse
Aoki, Yoshitsugu, Nakamura, Akinori, Yokota, Toshifumi, Saito, Takashi, Okazawa, Hitoshi, Nagata, Tetsuya, Takeda, Shin'ichi
Published in Molecular therapy (01.11.2010)
Published in Molecular therapy (01.11.2010)
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Bodywide skipping of exons 45–55 in dystrophic mdx52 mice by systemic antisense delivery
Aoki, Yoshitsugu, Yokota, Toshifumi, Nagata, Tetsuya, Nakamura, Akinori, Tanihata, Jun, Saito, Takashi, Duguez, Stephanie M. R, Nagaraju, Kanneboyina, Hoffman, Eric P, Partridge, Terence, Takeda, Shin'ichi
Published in Proceedings of the National Academy of Sciences - PNAS (21.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.08.2012)
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Development of Therapeutic RNA Manipulation for Muscular Dystrophy
Saifullah, Motohashi, Norio, Tsukahara, Toshifumi, Aoki, Yoshitsugu
Published in Frontiers in genome editing (10.05.2022)
Published in Frontiers in genome editing (10.05.2022)
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Quantitative Antisense Screening and Optimization for Exon 51 Skipping in Duchenne Muscular Dystrophy
Echigoya, Yusuke, Lim, Kenji Rowel Q., Trieu, Nhu, Bao, Bo, Miskew Nichols, Bailey, Vila, Maria Candida, Novak, James S., Hara, Yuko, Lee, Joshua, Touznik, Aleksander, Mamchaoui, Kamel, Aoki, Yoshitsugu, Takeda, Shin’ichi, Nagaraju, Kanneboyina, Mouly, Vincent, Maruyama, Rika, Duddy, William, Yokota, Toshifumi
Published in Molecular therapy (01.11.2017)
Published in Molecular therapy (01.11.2017)
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Journal Article
Antisense PMO cocktails effectively skip dystrophin exons 45-55 in myotubes transdifferentiated from DMD patient fibroblasts
Lee, Joshua, Echigoya, Yusuke, Duddy, William, Saito, Takashi, Aoki, Yoshitsugu, Takeda, Shin'ichi, Yokota, Toshifumi
Published in PloS one (17.05.2018)
Published in PloS one (17.05.2018)
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Journal Article
Exon Skipping in Directly Reprogrammed Myotubes Obtained from Human Urine-Derived Cells
Takizawa, Hotake, Sato, Mitsuto, Aoki, Yoshitsugu
Published in Journal of visualized experiments (07.05.2020)
Published in Journal of visualized experiments (07.05.2020)
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