Bundling of mRNA strands inside polyion complexes improves mRNA delivery efficiency in vitro and in vivo
Koji, Kyoko, Yoshinaga, Naoto, Mochida, Yuki, Hong, Taehun, Miyazaki, Takuya, Kataoka, Kazunori, Osada, Kensuke, Cabral, Horacio, Uchida, Satoshi
Published in Biomaterials (01.12.2020)
Published in Biomaterials (01.12.2020)
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Journal Article
PEG-OligoRNA Hybridization of mRNA for Developing Sterically Stable Lipid Nanoparticles toward In Vivo Administration
Kurimoto, Shota, Yoshinaga, Naoto, Igarashi, Kazunori, Matsumoto, Yu, Cabral, Horacio, Uchida, Satoshi
Published in Molecules (Basel, Switzerland) (03.04.2019)
Published in Molecules (Basel, Switzerland) (03.04.2019)
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Journal Article
Enhanced Intracellular Delivery of siRNA by Controlling ATP‐Responsivity of Phenylboronic Acid‐Functionalized Polyion Complex Micelles
Naito, Mitsuru, Yoshinaga, Naoto, Ishii, Takehiko, Matsumoto, Akira, Miyahara, Yuji, Miyata, Kanjiro, Kataoka, Kazunori
Published in Macromolecular bioscience (01.01.2018)
Published in Macromolecular bioscience (01.01.2018)
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Journal Article
Bridging mRNA and Polycation Using RNA Oligonucleotide Derivatives Improves the Robustness of Polyplex Micelles for Efficient mRNA Delivery
Yoshinaga, Naoto, Uchida, Satoshi, Dirisala, Anjaneyulu, Naito, Mitsuru, Koji, Kyoko, Osada, Kensuke, Cabral, Horacio, Kataoka, Kazunori
Published in Advanced healthcare materials (01.05.2022)
Published in Advanced healthcare materials (01.05.2022)
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Journal Article
PEGylation of mRNA by Hybridization of Complementary PEG-RNA Oligonucleotides Stabilizes mRNA without Using Cationic Materials
Yoshinaga, Naoto, Naito, Mitsuru, Tachihara, Yoshihiro, Boonstra, Eger, Osada, Kensuke, Cabral, Horacio, Uchida, Satoshi
Published in Pharmaceutics (27.05.2021)
Published in Pharmaceutics (27.05.2021)
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Journal Article
Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration
Yoshinaga, Naoto, Ishii, Takehiko, Naito, Mitsuru, Endo, Taisuke, Uchida, Satoshi, Cabral, Horacio, Osada, Kensuke, Kataoka, Kazunori
Published in Journal of the American Chemical Society (27.12.2017)
Published in Journal of the American Chemical Society (27.12.2017)
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Journal Article
mRNA loading into ATP-responsive polyplex micelles with optimal density of phenylboronate ester crosslinking to balance robustness in the biological milieu and intracellular translational efficiency
Yoshinaga, Naoto, Uchida, Satoshi, Dirisala, Anjaneyulu, Naito, Mitsuru, Osada, Kensuke, Cabral, Horacio, Kataoka, Kazunori
Published in Journal of controlled release (10.02.2021)
Published in Journal of controlled release (10.02.2021)
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Journal Article
Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection
Yoshinaga, Naoto, Uchida, Satoshi, Naito, Mitsuru, Osada, Kensuke, Cabral, Horacio, Kataoka, Kazunori
Published in Biomaterials (01.03.2019)
Published in Biomaterials (01.03.2019)
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Journal Article
Bundling mRNA Strands to Prepare Nano‐Assemblies with Enhanced Stability Towards RNase for In Vivo Delivery
Yoshinaga, Naoto, Cho, Eol, Koji, Kyoko, Mochida, Yuki, Naito, Mitsuru, Osada, Kensuke, Kataoka, Kazunori, Cabral, Horacio, Uchida, Satoshi
Published in Angewandte Chemie International Edition (12.08.2019)
Published in Angewandte Chemie International Edition (12.08.2019)
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Journal Article
Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination
Uchida, Satoshi, Yoshinaga, Naoto, Yanagihara, Kayoko, Yuba, Eiji, Kataoka, Kazunori, Itaka, Keiji
Published in Biomaterials (01.01.2018)
Published in Biomaterials (01.01.2018)
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Journal Article
Comb-structured mRNA vaccine tethered with short double-stranded RNA adjuvants maximizes cellular immunity for cancer treatment
Tockary, Theofilus A, Abbasi, Saed, Matsui-Masai, Miki, Hayashi, Akimasa, Yoshinaga, Naoto, Boonstra, Eger, Wang, Zheng, Fukushima, Shigeto, Kataoka, Kazunori, Uchida, Satoshi
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.2023)
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Trans Influence of Oxo and Dithiolene Coordination in Oxidized Models of Molybdenum Oxidoreductase: Synthesis, Structures, and Properties of Q2[MoVIO2(1,2-benzenedithiolato)2] (Q = NEt4, PPh4) and Related Complexes
Ueyama, Norikazu, Oku, Hiroyuki, Kondo, Mitsuru, Okamura, Taka-aki, Yoshinaga, Naoto, Nakamura, Akira
Published in Inorganic chemistry (31.01.1996)
Published in Inorganic chemistry (31.01.1996)
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Design of an Artificial Peptide Inspired by Transmembrane Mitochondrial Protein for Escorting Exogenous DNA into the Mitochondria to Restore their Functions by Simultaneous Multiple Gene Expression (Adv. Funct. Mater. 8/2024)
Yoshinaga, Naoto, Miyamoto, Takaaki, Odahara, Masaki, Takeda‐Kamiya, Noriko, Toyooka, Kiminori, Nara, Seia, Nishimura, Haruna, Ling, Feng, Su'etsugu, Masayuki, Yoshida, Minoru, Numata, Keiji
Published in Advanced functional materials (19.02.2024)
Published in Advanced functional materials (19.02.2024)
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Journal Article
Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability
Dirisala, Anjaneyulu, Uchida, Satoshi, Tockary, Theofilus A., Yoshinaga, Naoto, Li, Junjie, Osawa, Shigehito, Gorantla, Lahari, Fukushima, Shigeto, Osada, Kensuke, Kataoka, Kazunori
Published in Journal of drug targeting (03.07.2019)
Published in Journal of drug targeting (03.07.2019)
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