Discovery of (1R,2S)‑2-{[(2,4-Dimethylpyrimidin-5-yl)oxy]methyl}-2-(3-fluorophenyl)‑N‑(5-fluoropyridin-2-yl)cyclopropanecarboxamide (E2006): A Potent and Efficacious Oral Orexin Receptor Antagonist
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Published in Journal of medicinal chemistry (11.06.2015)
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Design, synthesis, and structure–activity relationships of a series of novel N-aryl-2-phenylcyclopropanecarboxamide that are potent and orally active orexin receptor antagonists
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Published in Bioorganic & medicinal chemistry (01.11.2014)
Published in Bioorganic & medicinal chemistry (01.11.2014)
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Corrigendum to “Design, synthesis, and structure–activity relationships of a series of novel N-aryl-2-phenylcyclopropanecarboxamide that are potent and orally active orexin receptor antagonists” [Bioorg. Med. Chem. 22 (2014) 6071–6088]
Yoshida, Yu, Terauchi, Taro, Naoe, Yoshimitsu, Kazuta, Yuji, Ozaki, Fumihiro, Beuckmann, Carsten T., Nakagawa, Makoto, Suzuki, Michiyuki, Kushida, Ikuo, Takenaka, Osamu, Ueno, Takashi, Yonaga, Masahiro
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Published in Bioorganic & medicinal chemistry (01.07.2015)
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Published in Tetrahedron letters (16.04.1998)
Published in Tetrahedron letters (16.04.1998)
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pH dependent cycloaromatization of enediyne model compounds via enyne-allene intermediates
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Published in Tetrahedron letters (11.12.1995)
Published in Tetrahedron letters (11.12.1995)
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Year of Publication 30.09.2019
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Year of Publication 30.09.2019
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METHODS AND COMPOUNDS USEFUL IN THE SYNTHESIS OF OREXIN-2 RECEPTOR ANTAGONISTS
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Year of Publication 24.09.2019
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METHODS AND COMPOUNDS USEFUL IN THE SYNTHESIS OF OREXIN-2 RECEPTOR ANTAGONISTS
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Year of Publication 03.04.2019
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Cycloaromatization of enediyne model compounds via a reaction cascade triggered by hydrolysis of the α-alkynylmalonates
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Published in Tetrahedron letters (05.02.1996)
Published in Tetrahedron letters (05.02.1996)
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composto ciclopropano antagonista de receptor da orexina e composição farmacêutica
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Year of Publication 31.08.2015
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