Antitumor Activity of ZSTK474, a New Phosphatidylinositol 3-Kinase Inhibitor
Yaguchi, Shin-ichi, Fukui, Yasuhisa, Koshimizu, Ichiro, Yoshimi, Hisashi, Matsuno, Toshiyuki, Gouda, Hiroaki, Hirono, Shuichi, Yamazaki, Kanami, Yamori, Takao
Published in JNCI : Journal of the National Cancer Institute (19.04.2006)
Published in JNCI : Journal of the National Cancer Institute (19.04.2006)
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Basal expression of insulin‐like growth factor 1 receptor determines intrinsic resistance of cancer cells to a phosphatidylinositol 3‐kinase inhibitor ZSTK474
Isoyama, Sho, Kajiwara, Gensei, Tamaki, Naomi, Okamura, Mutsumi, Yoshimi, Hisashi, Nakamura, Naoki, Kawamura, Kento, Nishimura, Yumiko, Namatame, Nachi, Yamori, Takao, Dan, Shingo
Published in Cancer science (01.02.2015)
Published in Cancer science (01.02.2015)
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Journal Article
Antiangiogenic effect of ZSTK474, a novel phosphatidylinositol 3-kinase inhibitor
Kong, Dexin, Okamura, Mutsumi, Yoshimi, Hisashi, Yamori, Takao
Published in European journal of cancer (1990) (01.03.2009)
Published in European journal of cancer (1990) (01.03.2009)
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Journal Article
ZSTK474, a specific phosphatidylinositol 3-kinase inhibitor, induces G1 arrest of the cell cycle in vivo
Dan, Shingo, Okamura, Mutsumi, Mukai, Yumiko, Yoshimi, Hisashi, Inoue, Yasumichi, Hanyu, Aki, Sakaue-Sawano, Asako, Imamura, Takeshi, Miyawaki, Atsushi, Yamori, Takao
Published in European journal of cancer (1990) (01.04.2012)
Published in European journal of cancer (1990) (01.04.2012)
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Development of an Immunohistochemical Protein Quantification System in Conjunction with Tissue Microarray Technology for Identifying Predictive Biomarkers for Phosphatidylinositol 3-Kinase Inhibitors
Isoyama, Sho, Yoshimi, Hisashi, Dan, Shingo, Okamura, Mutsumi, Seki, Mariko, Irimura, Tatsuro, Yamori, Takao
Published in Biological & pharmaceutical bulletin (2012)
Published in Biological & pharmaceutical bulletin (2012)
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Effectiveness of combined treatment using X‐rays and a phosphoinositide 3‐kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and in vivo
Anzai, Kazunori, Sekine‐Suzuki, Emiko, Ueno, Megumi, Okamura, Mutsumi, Yoshimi, Hisashi, Dan, Shingo, Yaguchi, Shin‐ichi, Enami, Jumpei, Yamori, Takao, Okayasu, Ryuichi
Published in Cancer science (01.06.2011)
Published in Cancer science (01.06.2011)
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Development of an Immunohistochemical Protein Quantification System in Conjunction with Tissue Microarray Technology for Identifying Predictive Biomarkers for Phosphatidylinositol 3-Kinase Inhibitors
Sho Isoyama, Hisashi Yoshimi, Shingo Dan, Mutsumi Okamura, Mariko Seki, Tatsuro Irimura, Takao Yamori
Published in Biological and Pharmaceutical Bulletin (01.09.2012)
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Published in Biological and Pharmaceutical Bulletin (01.09.2012)
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Abstract A43: Basal expression of insulin-like growth factor 1 receptor determines intrinsic resistance of cancer cells to a PI3K inhibitor ZSTK474
Isoyama, Sho, Kajiwara, Gensei, Tamaki, Naomi, Mutsumi, Okamura, Yoshimi, Hisashi, Nakamura, Naoki, Nishimura, Yumiko, Yamori, Takao, Dan, Shingo
Published in Molecular cancer therapeutics (01.07.2015)
Published in Molecular cancer therapeutics (01.07.2015)
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Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G{sub 0}/G{sub 1} arrest
Dan, Shingo, Yoshimi, Hisashi, Research Laboratory, Zenyaku-Kogyo Co., Ltd., 2-23-7 Ohizumi-machi, Nerima-ku, Tokyo 178-0062, Okamura, Mutsumi, Mukai, Yumiko, Yamori, Takao
Published in Biochemical and biophysical research communications (30.01.2009)
Published in Biochemical and biophysical research communications (30.01.2009)
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Abstract C96: Development of combination therapy with an IGF1R inhibitor and a PI3K inhibitor ZSTK474 in cancer cells exhibiting the intrinsic resistance to PI3K inhibitors
Isoyama, Sho, Kajiwara, Gensei, Tamaki, Naomi, Yoshimi, Hisashi, Nakamura, Naoki, Okamura, Mutsumi, Nishimura, Yumiko, Yamori, Takao, Dan, Shingo
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Abstract 2493: Inhibition of phosphoinositide 3-kinase suppressed growth of cancer cells with PIK3CA mutations or loss of PTEN expression via G0/G1 arrest of cell cycle but not apoptosis
Dan, Shingo, Okamura, Mutsumi, Yoshimi, Hisashi, Mukai, Yumiko, Yamazaki, Kanami, Inoue, Yasumichi, Hanyu, Aki, Imamura, Takeshi, Sakaue-Sawano, Asako, Miyawaki, Atsushi, Yamori, Takao
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Treatment of prostate cancer, melanoma or hepatic cancer
SAITOH KENICHI, YAGUCHI SHINICHI, KOSHIMIZU ICHIRO, MATSUNO TOSHIYUKI, TSUCHIDA YOSHIO, YOSHIMI HISASHI, WATANABE TETSUO
Year of Publication 18.10.2007
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Year of Publication 18.10.2007
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