Next-Generation Cancer Immunotherapy Targeting Glypican-3
Shimizu, Yasuhiro, Suzuki, Toshihiro, Yoshikawa, Toshiaki, Endo, Itaru, Nakatsura, Tetsuya
Published in Frontiers in oncology (10.04.2019)
Published in Frontiers in oncology (10.04.2019)
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Aberrant splicing isoforms detected by full-length transcriptome sequencing as transcripts of potential neoantigens in non-small cell lung cancer
Oka, Miho, Xu, Liu, Suzuki, Toshihiro, Yoshikawa, Toshiaki, Sakamoto, Hiromi, Uemura, Hayato, Yoshizawa, Akiyasu C, Suzuki, Yutaka, Nakatsura, Tetsuya, Ishihama, Yasushi, Suzuki, Ayako, Seki, Masahide
Published in Genome Biology (04.01.2021)
Published in Genome Biology (04.01.2021)
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Peptide vaccine as an adjuvant therapy for glypican‐3‐positive hepatocellular carcinoma induces peptide‐specific CTLs and improves long prognosis
Taniguchi, Masatake, Mizuno, Shoichi, Yoshikawa, Toshiaki, Fujinami, Norihiro, Sugimoto, Motokazu, Kobayashi, Shin, Takahashi, Shinichiro, Konishi, Masaru, Gotohda, Naoto, Nakatsura, Tetsuya
Published in Cancer science (01.08.2020)
Published in Cancer science (01.08.2020)
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Cancer immunotherapy‐targeted glypican‐3 or neoantigens
Shimizu, Yasuhiro, Suzuki, Toshihiro, Yoshikawa, Toshiaki, Tsuchiya, Nobuhiro, Sawada, Yu, Endo, Itaru, Nakatsura, Tetsuya
Published in Cancer science (01.03.2018)
Published in Cancer science (01.03.2018)
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Efficacy of immunotherapy targeting the neoantigen derived from epidermal growth factor receptor T790M/C797S mutation in non–small cell lung cancer
Akazawa, Yu, Saito, Yuki, Yoshikawa, Toshiaki, Saito, Keigo, Nosaka, Kazuto, Shimomura, Manami, Mizuno, Shoichi, Nakamoto, Yasunari, Nakatsura, Tetsuya
Published in Cancer science (01.08.2020)
Published in Cancer science (01.08.2020)
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Heat shock protein 105 peptide vaccine could induce antitumor immune reactions in a phase I clinical trial
Shimizu, Yasuhiro, Yoshikawa, Toshiaki, Kojima, Takashi, Shoda, Kayoko, Nosaka, Kazuto, Mizuno, Shoichi, Wada, Satoshi, Fujimoto, Yuki, Sasada, Tetsuro, Kohashi, Kenichi, Bando, Hideaki, Endo, Itaru, Nakatsura, Tetsuya
Published in Cancer science (01.10.2019)
Published in Cancer science (01.10.2019)
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Phase I Trial of a Glypican-3―Derived Peptide Vaccine for Advanced Hepatocellular Carcinoma: Immunologic Evidence and Potential for Improving Overall Survival
SAWADA, Yu, YOSHIKAWA, Toshiaki, NAKAGOHRI, Toshio, TAKAHASHI, Shinichiro, GOTOHDA, Naoto, TAKAYAMA, Tadatoshi, YAMAO, Kenji, UESAKA, Katsuhiko, FURUSE, Junji, KINOSHITA, Taira, NAKATSURA, Tetsuya, NOBUOKA, Daisuke, SHIRAKAWA, Hirofumi, KURONUMA, Toshimitsu, MOTOMURA, Yutaka, MIZUNO, Shoichi, ISHII, Hiroshi, NAKACHI, Kohei, KONISHI, Masaru
Published in Clinical cancer research (01.07.2012)
Published in Clinical cancer research (01.07.2012)
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HLA‐A2‐restricted glypican‐3 peptide‐specific CTL clones induced by peptide vaccine show high avidity and antigen‐specific killing activity against tumor cells
Yoshikawa, Toshiaki, Nakatsugawa, Munehide, Suzuki, Shiro, Shirakawa, Hirofumi, Nobuoka, Daisuke, Sakemura, Noriko, Motomura, Yutaka, Tanaka, Yukie, Hayashi, Shin‐Ichi, Nakatsura, Tetsuya
Published in Cancer science (01.05.2011)
Published in Cancer science (01.05.2011)
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Immunological efficacy of glypican-3 peptide vaccine in patients with advanced hepatocellular carcinoma
Tsuchiya, Nobuhiro, Yoshikawa, Toshiaki, Fujinami, Norihiro, Saito, Keigo, Mizuno, Shoichi, Sawada, Yu, Endo, Itaru, Nakatsura, Tetsuya
Published in Oncoimmunology (03.10.2017)
Published in Oncoimmunology (03.10.2017)
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Efficacy of the NCCV Cocktail‐1 vaccine for refractory pediatric solid tumors: A phase I clinical trial
Akazawa, Yu, Hosono, Ako, Yoshikawa, Toshiaki, Kaneda, Hide, Nitani, Chika, Hara, Junichi, Kinoshita, Yoshiaki, Kohashi, Kenichi, Manabe, Atsushi, Fukutani, Miki, Wakabayashi, Masashi, Sato, Akihiro, Shoda, Kayoko, Shimomura, Manami, Mizuno, Shoichi, Nakamoto, Yasunari, Nakatsura, Tetsuya
Published in Cancer science (01.12.2019)
Published in Cancer science (01.12.2019)
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Selection of highly responsive T cell receptors by an analysis combining the expression of multiple markers
Ha, My, Hamana, Hiroshi, Shitaoka, Kiyomi, Hayee, Abdul, Kobayashi, Eiji, Yoshikawa, Toshiaki, Nakatsura, Tetsuya, Saikawa, Reiko, Sato, Eri, Osawa, Mitsujiro, Hitoshi, Yasumichi, Dang, Tung, Ozawa, Tatsuhiko, Kishi, Hiroyuki
Published in Cancer science (01.06.2023)
Published in Cancer science (01.06.2023)
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Higher human lymphocyte antigen class I expression in early‐stage cancer cells leads to high sensitivity for cytotoxic T lymphocytes
Akazawa, Yu, Nobuoka, Daisuke, Takahashi, Mari, Yoshikawa, Toshiaki, Shimomura, Manami, Mizuno, Shoichi, Fujiwara, Toshiyoshi, Nakamoto, Yasunari, Nakatsura, Tetsuya
Published in Cancer science (01.06.2019)
Published in Cancer science (01.06.2019)
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Phase I study of glypican-3-derived peptide vaccine therapy for patients with refractory pediatric solid tumors
Tsuchiya, Nobuhiro, Hosono, Ako, Yoshikawa, Toshiaki, Shoda, Kayoko, Nosaka, Kazuto, Shimomura, Manami, Hara, Junichi, Nitani, Chika, Manabe, Atsushi, Yoshihara, Hiroki, Hosoya, Yosuke, Kaneda, Hide, Kinoshita, Yoshiaki, Kohashi, Kenichi, Yoshimura, Kenichi, Fujinami, Norihiro, Saito, Keigo, Mizuno, Shoichi, Nakatsura, Tetsuya
Published in Oncoimmunology (02.01.2018)
Published in Oncoimmunology (02.01.2018)
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Vaccination with liposome-coupled glypican-3-derived epitope peptide stimulates cytotoxic T lymphocytes and inhibits GPC3-expressing tumor growth in mice
Iwama, Tatsuaki, Uchida, Tetsuya, Sawada, Yu, Tsuchiya, Nobuhiro, Sugai, Shiori, Fujinami, Norihiro, Shimomura, Manami, Yoshikawa, Toshiaki, Zhang, Rong, Uemura, Yasushi, Nakatsura, Tetsuya
Published in Biochemical and biophysical research communications (01.01.2016)
Published in Biochemical and biophysical research communications (01.01.2016)
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Protocol to measure human IL-6 secretion from CAR T cell-primed macrophage and monocyte lineage cells in vitro and in vivo using humanized mice
Nguyen, Thao, Yoshikawa, Toshiaki, Ito, Yusuke, Kasuya, Hitomi, Nakashima, Takahiro, Okamoto, Sachiko, Amaishi, Yasunori, Zhang, Haosong, Li, Yang, Matsukawa, Tetsuya, Inoue, Satoshi, Kagoya, Yuki
Published in STAR protocols (01.12.2024)
Published in STAR protocols (01.12.2024)
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CD83 expression characterizes precursor exhausted T cell population
Wu, Zhiwen, Yoshikawa, Toshiaki, Inoue, Satoshi, Ito, Yusuke, Kasuya, Hitomi, Nakashima, Takahiro, Zhang, Haosong, Kotaka, Saki, Hosoda, Waki, Suzuki, Shiro, Kagoya, Yuki
Published in Communications biology (11.03.2023)
Published in Communications biology (11.03.2023)
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Glypican‐3 could be an effective target for immunotherapy combined with chemotherapy against ovarian clear cell carcinoma
Suzuki, Shiro, Yoshikawa, Toshiaki, Hirosawa, Tomoya, Shibata, Kiyosumi, Kikkawa, Fumitaka, Akatsuka, Yoshiki, Nakatsura, Tetsuya
Published in Cancer science (01.09.2011)
Published in Cancer science (01.09.2011)
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First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors
Shitara, Kohei, Ueha, Satoshi, Shichino, Shigeyuki, Aoki, Hiroyasu, Ogiwara, Haru, Nakatsura, Tetsuya, Suzuki, Toshihiro, Shimomura, Manami, Yoshikawa, Toshiaki, Shoda, Kayoko, Kitano, Shigehisa, Yamashita, Makiko, Nakayama, Takayuki, Sato, Akihiro, Kuroda, Sakiko, Wakabayashi, Masashi, Nomura, Shogo, Yokochi, Shoji, Ito, Satoru, Matsushima, Kouji, Doi, Toshihiko
Published in Journal for immunotherapy of cancer (24.07.2019)
Published in Journal for immunotherapy of cancer (24.07.2019)
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Decreased NKG2D Expression on CD8+ T Cell Is Involved in Immune Evasion in Patients with Gastric Cancer
OSAKI, Tomohiro, SAITO, Hiroaki, YOSHIKAWA, Toshiaki, MATSUMOTO, Sachiko, TATEBE, Shigeru, TSUJITANI, Shunichi, IKEGUCHI, Masahide
Published in Clinical cancer research (15.01.2007)
Published in Clinical cancer research (15.01.2007)
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Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model
Fujinami, Norihiro, Yoshikawa, Toshiaki, Sawada, Yu, Shimomura, Manami, Iwama, Tatsuaki, Sugai, Shiori, Kitano, Shigehisa, Uemura, Yasushi, Nakatsura, Tetsuya
Published in Biochemistry and biophysics reports (01.03.2016)
Published in Biochemistry and biophysics reports (01.03.2016)
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