Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase
Newman, Joseph A., Douangamath, Alice, Yadzani, Setayesh, Yosaatmadja, Yuliana, Aimon, Antony, Brandão-Neto, José, Dunnett, Louise, Gorrie-stone, Tyler, Skyner, Rachael, Fearon, Daren, Schapira, Matthieu, von Delft, Frank, Gileadi, Opher
Published in Nature communications (11.08.2021)
Published in Nature communications (11.08.2021)
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Journal Article
TAS‐120 Cancer Target Binding: Defining Reactivity and Revealing the First Fibroblast Growth Factor Receptor 1 (FGFR1) Irreversible Structure
Kalyukina, Maria, Yosaatmadja, Yuliana, Middleditch, Martin J., Patterson, Adam V., Smaill, Jeff B., Squire, Christopher J.
Published in ChemMedChem (19.02.2019)
Published in ChemMedChem (19.02.2019)
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Journal Article
Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed
Yosaatmadja, Yuliana, Silva, Shevan, Dickson, James M., Patterson, Adam V., Smaill, Jeff B., Flanagan, Jack U., McKeage, Mark J., Squire, Christopher J.
Published in Journal of structural biology (01.12.2015)
Published in Journal of structural biology (01.12.2015)
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Journal Article
Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily
Yeung, Ho, Squire, Christopher J., Yosaatmadja, Yuliana, Panjikar, Santosh, López, Gemma, Molina, Antonio, Baker, Edward N., Harris, Paul W. R., Brimble, Margaret A.
Published in Angewandte Chemie (International ed.) (04.07.2016)
Published in Angewandte Chemie (International ed.) (04.07.2016)
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Journal Article
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3
Flanagan, Jack U, Yosaatmadja, Yuliana, Teague, Rebecca M, Chai, Matilda Z L, Turnbull, Andrew P, Squire, Christopher J
Published in PloS one (28.08.2012)
Published in PloS one (28.08.2012)
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Journal Article
Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development
Imprachim, Nergis, Yosaatmadja, Yuliana, Newman, Joseph A
Published in Nucleic acids research (11.01.2023)
Published in Nucleic acids research (11.01.2023)
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Journal Article
Abstract 1398 A very cool and novel phosphofructokinase sheds light on the evolution of substrate specificity and on the metabolic networks in our closest prokaryotic relatives
Patrick, Wayne, Compton, Jordan, Yosaatmadja, Yuliana, Bashiri, Ghader, Vickers, Chelsea
Published in The Journal of biological chemistry (01.03.2024)
Published in The Journal of biological chemistry (01.03.2024)
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Journal Article
The SNM1A DNA repair nuclease
Baddock, Hannah T., Yosaatmadja, Yuliana, Newman, Joseph A., Schofield, Christopher J., Gileadi, Opher, McHugh, Peter J.
Published in DNA repair (01.11.2020)
Published in DNA repair (01.11.2020)
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Journal Article
Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification
Baddock, Hannah T, Brolih, Sanja, Yosaatmadja, Yuliana, Ratnaweera, Malitha, Bielinski, Marcin, Swift, Lonnie P, Cruz-Migoni, Abimael, Fan, Haitian, Keown, Jeremy R, Walker, Alexander P, Morris, Garrett M, Grimes, Jonathan M, Fodor, Ervin, Schofield, Christopher J, Gileadi, Opher, McHugh, Peter J
Published in Nucleic acids research (22.02.2022)
Published in Nucleic acids research (22.02.2022)
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Journal Article
Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition
Yosaatmadja, Yuliana, Baddock, Hannah T, Newman, Joseph A, Bielinski, Marcin, Gavard, Angeline E, Mukhopadhyay, Shubhashish M M, Dannerfjord, Adam A, Schofield, Christopher J, McHugh, Peter J, Gileadi, Opher
Published in Nucleic acids research (20.09.2021)
Published in Nucleic acids research (20.09.2021)
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Journal Article
A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family
Baddock, Hannah T, Newman, Joseph A, Yosaatmadja, Yuliana, Bielinski, Marcin, Schofield, Christopher J, Gileadi, Opher, McHugh, Peter J
Published in Nucleic acids research (20.09.2021)
Published in Nucleic acids research (20.09.2021)
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Journal Article
Cell-active small molecule inhibitors validate the SNM1A DNA repair nuclease as a cancer target
Bielinski, Marcin, Henderson, Lucy R, Yosaatmadja, Yuliana, Swift, Lonnie P, Baddock, Hannah T, Bowen, Matthew J, Brem, Jürgen, Jones, Philip S, McElroy, Stuart P, Morrison, Angus, Speake, Michael, van Boeckel, Stan, van Doornmalen, Els, van Groningen, Jan, van den Hurk, Helma, Gileadi, Opher, Newman, Joseph A, McHugh, Peter J, Schofield, Christopher J
Published in Chemical science (Cambridge) (29.05.2024)
Published in Chemical science (Cambridge) (29.05.2024)
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Journal Article
2-Oxo-3, 4-dihydropyrimido[4, 5-d]pyrimidinyl derivatives as new irreversible pan fibroblast growth factor receptor (FGFR) inhibitors
Li, Xueqiang, Guise, Christopher P., Taghipouran, Rana, Yosaatmadja, Yuliana, Ashoorzadeh, Amir, Paik, Woo-Kyong, Squire, Christopher J., Jiang, Shuang, Luo, Jinfeng, Xu, Yong, Tu, Zheng-Chao, Lu, Xiaoyun, Ren, Xiaomei, Patterson, Adam V., Smaill, Jeff B., Ding, Ke
Published in European journal of medicinal chemistry (28.07.2017)
Published in European journal of medicinal chemistry (28.07.2017)
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Journal Article
Rotational Freedom, Steric Hindrance, and Protein Dynamics Explain BLU554 Selectivity for the Hinge Cysteine of FGFR4
Lin, Xiaojing, Yosaatmadja, Yuliana, Kalyukina, Maria, Middleditch, Martin J, Zhang, Zhen, Lu, Xiaoyun, Ding, Ke, Patterson, Adam V, Smaill, Jeff B, Squire, Christopher J
Published in ACS medicinal chemistry letters (08.08.2019)
Published in ACS medicinal chemistry letters (08.08.2019)
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Journal Article
Structures of Human Peroxiredoxin 3 Suggest Self-Chaperoning Assembly that Maintains Catalytic State
Yewdall, N. Amy, Venugopal, Hariprasad, Desfosses, Ambroise, Abrishami, Vahid, Yosaatmadja, Yuliana, Hampton, Mark B., Gerrard, Juliet A., Goldstone, David C., Mitra, Alok K., Radjainia, Mazdak
Published in Structure (London) (06.07.2016)
Published in Structure (London) (06.07.2016)
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Journal Article
Cover Picture: Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily (Angew. Chem. Int. Ed. 28/2016)
Yeung, Ho, Squire, Christopher J., Yosaatmadja, Yuliana, Panjikar, Santosh, López, Gemma, Molina, Antonio, Baker, Edward N., Harris, Paul W. R., Brimble, Margaret A.
Published in Angewandte Chemie (International ed.) (04.07.2016)
Published in Angewandte Chemie (International ed.) (04.07.2016)
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Journal Article