TACH101, a first-in-class pan-inhibitor of KDM4 for treatment of gastrointestinal cancers
Perabo, Frank, Chandhasin, Chandtip, Yoo, Sanghee, Dang, Van, Del Rosario, Joselyn, Chen, Young K, Stafford, Jeffrey, Quake, Stephen, Clarke, Michael F.
Published in Journal of clinical oncology (01.02.2022)
Published in Journal of clinical oncology (01.02.2022)
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A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming
Son, Myung Jin, Jeong, Jae Kap, Kwon, Youjeong, Ryu, Jae-Sung, Mun, Seon Ju, Kim, Hye Jin, Kim, Sung-wuk, Yoo, Sanghee, Kook, Jiae, Lee, Hongbum, Kim, Janghwan, Chung, Kyung-Sook
Published in Experimental & molecular medicine (06.12.2018)
Published in Experimental & molecular medicine (06.12.2018)
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A High-Throughput Microphysiological Liver Chip System to Model Drug-Induced Liver Injury Using Human Liver Organoids
Meyer, Sophia R., Zhang, Charles J., Garcia, Max A., Procario, Megan C., Yoo, Sanghee, Jolly, Amber L., Kim, Sumin, Kim, Jiho, Baek, Kyusuk, Kersten, Roland D., Fontana, Robert J., Sexton, Jonathan Z.
Published in Gastro hep advances (2024)
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Identification of potent CNS-penetrant thiazolidinones as novel CGRP receptor antagonists
Joshi, Pramod, Anderson, Corey, Binch, Hayley, Hadida, Sabine, Yoo, Sanghee, Bergeron, Danielle, Decker, Caroline, terHaar, Ernst, Moore, Jonathan, Garcia-Guzman, Miguel, Termin, Andreas
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
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Repression of LKB1 by miR-17∼92 Sensitizes MYC-Dependent Lymphoma to Biguanide Treatment
Izreig, Said, Gariepy, Alexandra, Kaymak, Irem, Bridges, Hannah R., Donayo, Ariel O., Bridon, Gaëlle, DeCamp, Lisa M., Kitchen-Goosen, Susan M., Avizonis, Daina, Sheldon, Ryan D., Laister, Rob C., Minden, Mark D., Johnson, Nathalie A., Duchaine, Thomas F., Rudoltz, Marc S., Yoo, Sanghee, Pollak, Michael N., Williams, Kelsey S., Jones, Russell G.
Published in Cell reports. Medicine (19.05.2020)
Published in Cell reports. Medicine (19.05.2020)
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Refolding and Characterization of a Soluble Ectodomain Complex of the Calcitonin Gene-Related Peptide Receptor
Koth, Christopher M, Abdul-Manan, Norzehan, Lepre, Christopher A, Connolly, Peter J, Yoo, Sanghee, Mohanty, Arun K, Lippke, Judith A, Zwahlen, Jacque, Coll, Joyce T, Doran, John D, Garcia-Guzman, Miguel, Moore, Jonathan M
Published in Biochemistry (Easton) (09.03.2010)
Published in Biochemistry (Easton) (09.03.2010)
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Structure of the Carboxyl-Terminal Dimerization Domain of the HIV-1 Capsid Protein
Gamble, Theresa R., Yoo, Sanghee, Vajdos, Felix F., von Schwedler, Uta K., Worthylake, David K., Wang, Hui, McCutcheon, John P., Sundquist, Wesley I., Hill, Christopher P.
Published in Science (American Association for the Advancement of Science) (31.10.1997)
Published in Science (American Association for the Advancement of Science) (31.10.1997)
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Patient-derived tumor spheroid-induced angiogenesis preclinical platform for exploring therapeutic vulnerabilities in cancer
Ko, Jihoon, Hyung, Sujin, Heo, You Jeong, Jung, Sangmin, Kim, Seung Tae, Park, Se Hoon, Hong, Jung Yong, Lim, Sung Hee, Kim, Kyoung-Mee, Yoo, Sanghee, Jeon, Noo Li, Lee, Jeeyun
Published in Biomaterials (01.04.2024)
Published in Biomaterials (01.04.2024)
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Abstract 2128: TACH101, a first-in-class pan inhibitor of KDM4 histone lysine demethylases
Yoo, Sanghee, Chandhasin, Chandtip, Rosario, Joselyn R. Del, Chen, Young K., Stafford, Jeff, Quake, Stephen, Perabo, Frank, Clarke, Michael F.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Inhibition of histone lysine demethylases with TACH101, a first-in-class pan-inhibitor of KDM4
Chandhasin, Chandtip, Yoo, Sanghee, Del Rosario, Joselyn, Chen, Young K, Stafford, Jeffrey, Perabo, Frank, Clarke, Michael F.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Pharmacologic characterization of TACH101, a first-in-class KDM4 inhibitor for development as a cancer therapeutic
Yoo, Sanghee, Chandhasin, Chandtip, Del Rosario, Joselyn, Chen, Young K, Stafford, Jeffrey, Perabo, Frank, Clarke, Michael F.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Abstract P086: Identification of pharmacodynamic and sensitivity biomarkers for TACH101, a pan-inhibitor of KDM4 histone lysine demethylase
Perabo, Frank, Yoo, Sanghee, Chandhasin, Chandtip, Rosario, Joselyn Del, Chen, Young K., Filvaroff, Ellen, Stafford, Jeffrey A., Quake, Stephen, Clarke, Michael F.
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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Modulation of Oxidative Phosphorylation with IM156 Attenuates Mitochondrial Metabolic Reprogramming and Inhibits Pulmonary Fibrosis
Willette, Robert N, Mangrolia, Parth, Pondell, Stephen M, Lee, Christopher Young Woo, Yoo, Sanghee, Rudoltz, Marc S, Cowen, Benjamin R, Welsch, Dean J
Published in The Journal of pharmacology and experimental therapeutics (01.12.2021)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2021)
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First-in-human study of IM156, a novel potent biguanide oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced solid tumors
Janku, Filip, Beom, Seung-Hoon, Moon, Yong Wha, Kim, Tae Won, Shin, Young G., Yim, Dong-Seok, Kim, Gun Min, Kim, Hyo Song, Kim, Sun Young, Cheong, Jae-Ho, Lee, Young Woo, Geiger, Barb, Yoo, Sanghee, Thurston, Archie, Welsch, Dean, Rudoltz, Marc S., Rha, Sun Young
Published in Investigational new drugs (01.10.2022)
Published in Investigational new drugs (01.10.2022)
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Characterizing On-Chip Angiogenesis Induction in a Microphysiological System as a Functional Measure of Mesenchymal Stromal Cell Bioactivity
Lam, Johnny, Yu, James, Lee, Byungjun, Campagna, Courtney, Yoo, Sanghee, Baek, Kyusuk, Jeon, Noo Li, Sung, Kyung E
Published in Advanced biology (01.08.2024)
Published in Advanced biology (01.08.2024)
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