Search Results - "YONEKUBO SHIGERU" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Novel oestrogen receptor β-selective ligand reduces obesity and depressive-like behaviour in ovariectomized mice

Novel oestrogen receptor β-selective ligand reduces obesity and depressive-like behaviour in ovariectomized mice

by Sasayama, Daimei, Sugiyama, Nobuhiro, Yonekubo, Shigeru, Pawlak, Akiko, Murasawa, Hiroyasu, Nakamura, Mie, Hayashi, Morimichi, Ogawa, Takashi, Moro, Makoto, Washizuka, Shinsuke, Amano, Naoji, Hongo, Kazuhiro, Ohnota, Hideki
Published in Scientific reports (05.07.2017)

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Journal Article

d- and l-Quartz-Promoted Highly Enantioselective Synthesis of a Chiral Organic Compound

d- and l-Quartz-Promoted Highly Enantioselective Synthesis of a Chiral Organic Compound

by Soai, Kenso, Osanai, Shunji, Kadowaki, Kousuke, Yonekubo, Shigeru, Shibata, Takanori, Sato, Itaru
Published in Journal of the American Chemical Society (08.12.1999)

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Journal Article

Amplification of a Slight Enantiomeric Imbalance in Molecules Based on Asymmetric Autocatalysis: The First Correlation between High Enantiomeric Enrichment in a Chiral Molecule and Circularly Polarized Light

Amplification of a Slight Enantiomeric Imbalance in Molecules Based on Asymmetric Autocatalysis: The First Correlation between High Enantiomeric Enrichment in a Chiral Molecule and Circularly Polarized Light

by Shibata, Takanori, Yamamoto, Jun, Matsumoto, Naoko, Yonekubo, Shigeru, Osanai, Shunji, Soai, Kenso
Published in Journal of the American Chemical Society (25.11.1998)

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Journal Article

Highly Enantioselective Asymmetric Autocatalysis of Pyrimidin-5-yl Alkanol Induced by Chiral 1,3-Disubstituted Hydrocarbon Allenes

Highly Enantioselective Asymmetric Autocatalysis of Pyrimidin-5-yl Alkanol Induced by Chiral 1,3-Disubstituted Hydrocarbon Allenes

by Sato, Itaru, Matsueda, Yohei, Kadowaki, Kousuke, Yonekubo, Shigeru, Shibata, Takanori, Soai, Kenso
Published in Helvetica chimica acta (01.10.2002)

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Journal Article

Evaluating the correlation of binding affinities between isothermal titration calorimetry and fragment molecular orbital method of estrogen receptor beta with diarylpropionitrile (DPN) or DPN derivatives

Evaluating the correlation of binding affinities between isothermal titration calorimetry and fragment molecular orbital method of estrogen receptor beta with diarylpropionitrile (DPN) or DPN derivatives

by Handa, Chiaki, Yamazaki, Yuki, Yonekubo, Shigeru, Furuya, Noritaka, Momose, Takaki, Ozawa, Tomonaga, Furuishi, Takayuki, Fukuzawa, Kaori, Yonemochi, Etsuo
Published in The Journal of steroid biochemistry and molecular biology (01.09.2022)

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Journal Article

Synthesis and structure-activity relationships of 1-benzylindane derivatives as selective agonists for estrogen receptor beta

Synthesis and structure-activity relationships of 1-benzylindane derivatives as selective agonists for estrogen receptor beta

by Yonekubo, Shigeru, Fushimi, Nobuhiko, Miyagi, Takashi, Nakanishi, Osamu, Katsuno, Kenji, Ozawa, Motoyasu, Handa, Chiaki, Furuya, Noritaka, Muranaka, Hideyuki
Published in Bioorganic & medicinal chemistry (15.11.2016)

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Journal Article

Point‐to‐Point Ultra‐Remote Asymmetric Control with Flexible Linker

Point‐to‐Point Ultra‐Remote Asymmetric Control with Flexible Linker

by Kawasaki, Tsuneomi, Ishikawa, Yasuyuki, Minato, Yoshihiro, Otsuka, Takashi, Yonekubo, Shigeru, Sato, Itaru, Shibata, Takanori, Matsumoto, Arimasa, Soai, Kenso
Published in Chemistry : a European journal (05.01.2017)

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Journal Article

Structure–activity relationship studies of 4-benzyl-1H-pyrazol-3-yl β-d-glucopyranoside derivatives as potent and selective sodium glucose co-transporter 1 (SGLT1) inhibitors with therapeutic activity on postprandial hyperglycemia

Structure–activity relationship studies of 4-benzyl-1H-pyrazol-3-yl β-d-glucopyranoside derivatives as potent and selective sodium glucose co-transporter 1 (SGLT1) inhibitors with therapeutic activity on postprandial hyperglycemia

by Fushimi, Nobuhiko, Fujikura, Hideki, Shiohara, Hiroaki, Teranishi, Hirotaka, Shimizu, Kazuo, Yonekubo, Shigeru, Ohno, Kohsuke, Miyagi, Takashi, Itoh, Fumiaki, Shibazaki, Toshihide, Tomae, Masaki, Ishikawa-Takemura, Yukiko, Nakabayashi, Takeshi, Kamada, Noboru, Ozawa, Tomonaga, Kobayashi, Susumu, Isaji, Masayuki
Published in Bioorganic & medicinal chemistry (15.11.2012)

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Journal Article

Design, synthesis, and structure–activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl β-d-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1)

Design, synthesis, and structure–activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl β-d-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1)

by Fushimi, Nobuhiko, Teranishi, Hirotaka, Shimizu, Kazuo, Yonekubo, Shigeru, Ohno, Kohsuke, Miyagi, Takashi, Itoh, Fumiaki, Shibazaki, Toshihide, Tomae, Masaki, Ishikawa-Takemura, Yukiko, Nakabayashi, Takeshi, Kamada, Noboru, Yamauchi, Yuji, Kobayashi, Susumu, Isaji, Masayuki
Published in Bioorganic & medicinal chemistry (01.02.2013)

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Journal Article

Design, synthesis, and structure-activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl [beta]-d-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1)

Design, synthesis, and structure-activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl [beta]-d-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1)

by Fushimi, Nobuhiko, Teranishi, Hirotaka, Shimizu, Kazuo, Yonekubo, Shigeru, Ohno, Kohsuke, Miyagi, Takashi, Itoh, Fumiaki, Shibazaki, Toshihide, Tomae, Masaki, Ishikawa-Takemura, Yukiko, Nakabayashi, Takeshi, Kamada, Noboru, Yamauchi, Yuji, Kobayashi, Susumu, Isaji, Masayuki
Published in Bioorganic & medicinal chemistry (01.02.2013)

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Journal Article

Design, synthesis, and structure-activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl I2-d-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1)

Design, synthesis, and structure-activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl I2-d-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1)

by Fushimi, Nobuhiko, Teranishi, Hirotaka, Shimizu, Kazuo, Yonekubo, Shigeru, Ohno, Kohsuke, Miyagi, Takashi, Itoh, Fumiaki, Shibazaki, Toshihide, Tomae, Masaki, Ishikawa-Takemura, Yukiko, Nakabayashi, Takeshi, Kamada, Noboru, Yamauchi, Yuji, Kobayashi, Susumu, Isaji, Masayuki
Published in Bioorganic & medicinal chemistry (01.02.2013)

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Journal Article

Structure-activity relationship studies of 4-benzyl-1H-pyrazol-3-yl I2-d-glucopyranoside derivatives as potent and selective sodium glucose co-transporter 1 (SGLT1) inhibitors with therapeutic activity on postprandial hyperglycemia

Structure-activity relationship studies of 4-benzyl-1H-pyrazol-3-yl I2-d-glucopyranoside derivatives as potent and selective sodium glucose co-transporter 1 (SGLT1) inhibitors with therapeutic activity on postprandial hyperglycemia

by Fushimi, Nobuhiko, Fujikura, Hideki, Shiohara, Hiroaki, Teranishi, Hirotaka, Shimizu, Kazuo, Yonekubo, Shigeru, Ohno, Kohsuke, Miyagi, Takashi, Itoh, Fumiaki, Shibazaki, Toshihide, Tomae, Masaki, Ishikawa-Takemura, Yukiko, Nakabayashi, Takeshi, Kamada, Noboru, Ozawa, Tomonaga, Kobayashi, Susumu, Isaji, Masayuki
Published in Bioorganic & medicinal chemistry (01.11.2012)

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Journal Article

1-SUBSTITUTED-3-ß-D-GLUCOPYRANOSYLATED NITROGENOUS HETERO- CYCLIC COMPOUNDS AND MEDICINES CONTAINING THE SAME

1-SUBSTITUTED-3-ß-D-GLUCOPYRANOSYLATED NITROGENOUS HETERO- CYCLIC COMPOUNDS AND MEDICINES CONTAINING THE SAME

by FUSHIMI, NOBUHIKO, YONEKUBO, SHIGERU
Year of Publication 26.05.2006

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Patent

METHOD FOR PRODUCING FUSED-HETEROCYCLIC DERIVATIVE, AND PRODUCTION INTERMEDIATE THEREOF

METHOD FOR PRODUCING FUSED-HETEROCYCLIC DERIVATIVE, AND PRODUCTION INTERMEDIATE THEREOF

by SONEHARA, JUNICHI, KOBAYASHI, MAKOTO, OHNO, KOHSUKE, AINAI, TAKAYUKI, KASAI, KIYOSHI, YONEKUBO, SHIGERU
Year of Publication 26.03.2015

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Patent

METHOD FOR PRODUCING FUSED-HETEROCYCLIC DERIVATIVE, AND PRODUCTION INTERMEDIATE THEREOF

METHOD FOR PRODUCING FUSED-HETEROCYCLIC DERIVATIVE, AND PRODUCTION INTERMEDIATE THEREOF

by SONEHARA, JUNICHI, KOBAYASHI, MAKOTO, OHNO, KOHSUKE, AINAI, TAKAYUKI, KASAI, KIYOSHI, YONEKUBO, SHIGERU
Year of Publication 20.03.2014

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Patent

1-SUBSTITUTED-7-(ß-D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME

1-SUBSTITUTED-7-(ß-D-GLYCOPYRANOSYLOXY)(AZA)INDOLE COMPOUND AND PHARMACEUTICAL CONTAINING THE SAME

by OHNO, KOHSUKE, FUSHIMII, NOBUHIKO, YONEKUBO, SHIGERU
Year of Publication 24.08.2006

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Patent

NITROGENATED FUSED-RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE OF THE SAME FOR MEDICAL PURPOSES

NITROGENATED FUSED-RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE OF THE SAME FOR MEDICAL PURPOSES

by OHNO, KOHSUKE, FUSHIMI, NOBUHIKO, YONEKUBO, SHIGERU, MIYAGI, TAKASHI
Year of Publication 26.03.2009

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Patent

FUSED HETEROCYCLIC DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE DERIVATIVE, AND USE OF THE COMPOSITION FOR MEDICAL PURPOSES

FUSED HETEROCYCLIC DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE DERIVATIVE, AND USE OF THE COMPOSITION FOR MEDICAL PURPOSES

by OHNO, KOHSUKE, FUSHIMI, NOBUHIKO, KAMBARA, MIKIE, YONEKUBO, SHIGERU, MIYAGI, TAKASHI
Year of Publication 06.11.2008

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Patent

NITROGENATED FUSED RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE OF THE SAME FOR MEDICAL PURPOSES

NITROGENATED FUSED RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE OF THE SAME FOR MEDICAL PURPOSES

by OHNO, KOHSUKE, FUSHIMI, NOBUHIKO, KAMBARA, MIKIE, YONEKUBO, SHIGERU, MIYAGI, TAKASHI
Year of Publication 30.10.2008

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Patent

Derivado heterocíclico condensado, composición medicinal que contiene el mismo, y uso medicinal del mismo

Derivado heterocíclico condensado, composición medicinal que contiene el mismo, y uso medicinal del mismo

by MIYAGI, Takashi, YONEKUBO, Shigeru, FUSHIMI, Nobuhiko, OHNO, Kohsuke, OZAWA, Tomonaga
Year of Publication 26.10.2022

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Patent

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