TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis
Matsuo, Yo, Park, Jae-Hyun, Miyamoto, Takashi, Yamamoto, Shinji, Hisada, Shoji, Alachkar, Houda, Nakamura, Yusuke
Published in Science translational medicine (22.10.2014)
Published in Science translational medicine (22.10.2014)
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Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells
Kato, Taigo, Inoue, Hiroyuki, Imoto, Seiya, Tamada, Yoshinori, Miyamoto, Takashi, Matsuo, Yo, Nakamura, Yusuke, Park, Jae-Hyun
Published in Oncotarget (05.04.2016)
Published in Oncotarget (05.04.2016)
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Journal Article
WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer
Saloura, Vassiliki, Vougiouklakis, Theodore, Zewde, Makda, Deng, Xiaolan, Kiyotani, Kazuma, Park, Jae-Hyun, Matsuo, Yo, Lingen, Mark, Suzuki, Takehiro, Dohmae, Naoshi, Hamamoto, Ryuji, Nakamura, Yusuke
Published in Scientific reports (19.01.2017)
Published in Scientific reports (19.01.2017)
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Journal Article
TOPK (T‐LAK cell‐originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer
Park, Jae‐Hyun, Inoue, Hiroyuki, Kato, Taigo, Zewde, Makda, Miyamoto, Takashi, Matsuo, Yo, Salgia, Ravi, Nakamura, Yusuke
Published in Cancer science (01.03.2017)
Published in Cancer science (01.03.2017)
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Journal Article
Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer
Inoue, Hiroyuki, Kato, Taigo, Olugbile, Sope, Tamura, Kenji, Chung, Suyoun, Miyamoto, Takashi, Matsuo, Yo, Salgia, Ravi, Nakamura, Yusuke, Park, Jae-Hyun
Published in Oncotarget (22.03.2016)
Published in Oncotarget (22.03.2016)
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Journal Article
Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia
Alachkar, Houda, Mutonga, Martin B G, Metzeler, Klaus H, Fulton, Noreen, Malnassy, Gregory, Herold, Tobias, Spiekermann, Karsten, Bohlander, Stefan K, Hiddemann, Wolfgang, Matsuo, Yo, Stock, Wendy, Nakamura, Yusuke
Published in Oncotarget (15.12.2014)
Published in Oncotarget (15.12.2014)
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Journal Article
Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization
Yoshioka, Yuichiro, Suzuki, Takehiro, Matsuo, Yo, Tsurita, Giichiro, Watanabe, Toshiaki, Dohmae, Naoshi, Nakamura, Yusuke, Hamamoto, Ryuji
Published in Cancer medicine (Malden, MA) (01.07.2017)
Published in Cancer medicine (Malden, MA) (01.07.2017)
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Journal Article
Amyloid oligomer conformation in a group of natively folded proteins
Yoshiike, Yuji, Minai, Ryoichi, Matsuo, Yo, Chen, Yun-Ru, Kimura, Tetsuya, Takashima, Akihiko
Published in PloS one (18.09.2008)
Published in PloS one (18.09.2008)
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Journal Article
In Silico Functional Profiling of Small Molecules and Its Applications
Sato, Tomohiro, Matsuo, Yo, Honma, Teruki, Yokoyama, Shigeyuki
Published in Journal of medicinal chemistry (25.12.2008)
Published in Journal of medicinal chemistry (25.12.2008)
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Journal Article
SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1
Yoshioka, Yuichiro, Suzuki, Takehiro, Matsuo, Yo, Nakakido, Makoto, Tsurita, Giichiro, Simone, Cristiano, Watanabe, Toshiaki, Dohmae, Naoshi, Nakamura, Yusuke, Hamamoto, Ryuji
Published in Oncotarget (15.11.2016)
Published in Oncotarget (15.11.2016)
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Journal Article
Characterization of the Interaction between Interleukin-13 and Interleukin-13 Receptors
Arima, Kazuhiko, Sato, Kazuo, Tanaka, Go, Kanaji, Sachiko, Terada, Tohru, Honjo, Eijiro, Kuroki, Ryota, Matsuo, Yo, Izuhara, Kenji
Published in The Journal of biological chemistry (01.07.2005)
Published in The Journal of biological chemistry (01.07.2005)
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Journal Article
Solution Structure of the SEA Domain from the Murine Homologue of Ovarian Cancer Antigen CA125 (MUC16)
Maeda, Takeshi, Inoue, Makoto, Koshiba, Seizo, Yabuki, Takashi, Aoki, Masaaki, Nunokawa, Emi, Seki, Eiko, Matsuda, Takayoshi, Motoda, Yoko, Kobayashi, Atsuo, Hiroyasu, Fumiko, Shirouzu, Mikako, Terada, Takaho, Hayami, Nobuhiro, Ishizuka, Yoshiko, Shinya, Naoko, Tatsuguchi, Ayako, Yoshida, Mayumi, Hirota, Hiroshi, Matsuo, Yo, Tani, Kazutoshi, Arakawa, Takahiro, Carninci, Piero, Kawai, Jun, Hayashizaki, Yoshihide, Kigawa, Takanori, Yokoyama, Shigeyuki
Published in The Journal of biological chemistry (26.03.2004)
Published in The Journal of biological chemistry (26.03.2004)
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The Squamous Cell Carcinoma Antigen 2 Inhibits the Cysteine Proteinase Activity of a Major Mite Allergen, Der p 1
Sakata, Yasuhisa, Arima, Kazuhiko, Takai, Toshiro, Sakurai, Wataru, Masumoto, Kiyonari, Yuyama, Noriko, Suminami, Yoshinori, Kishi, Fumio, Yamashita, Tetsuji, Kato, Takeshi, Ogawa, Hideoki, Fujimoto, Kazuma, Matsuo, Yo, Sugita, Yuji, Izuhara, Kenji
Published in The Journal of biological chemistry (13.02.2004)
Published in The Journal of biological chemistry (13.02.2004)
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Journal Article
Comparative study on the structure and cytopathogenic activity of HIV Vpr/Vpx proteins
Khamsri, Boonruang, Murao, Fumiko, Yoshida, Akiko, Sakurai, Akiko, Uchiyama, Tsuneo, Shirai, Hiroki, Matsuo, Yo, Fujita, Mikako, Adachi, Akio
Published in Microbes and infection (2006)
Published in Microbes and infection (2006)
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Journal Article
Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer
Chung, Suyoun, Suzuki, Hanae, Miyamoto, Takashi, Takamatsu, Naofumi, Tatsuguchi, Ayako, Ueda, Koji, Kijima, Kyoko, Nakamura, Yusuke, Matsuo, Yo
Published in Oncotarget (01.12.2012)
Published in Oncotarget (01.12.2012)
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