N-치환된 테트라히드로티에노피리딘 유도체 및 이의 용도
YEUNG BRYAN KS, YOKOKAWA FUMIAKI, WANG GANG, SIMON OLIVER, YEO HUI QUAN, KOUNDE CYRILLE, ZOU BIN, SIM WEI LIN SANDRA
Year of Publication 03.03.2021
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Year of Publication 03.03.2021
Patent
Targeting Plasmodium PI(4)K to eliminate malaria
McNamara, Case W, Lee, Marcus Cs, Lim, Chek Shik, Lim, Siau Hoi, Roland, Jason, Simon, Oliver, Yeung, Bryan Ks, Chatterjee, Arnab K, McCormack, Susan L, Manary, Micah J, Zeeman, Anne-Marie, Dechering, Koen J, Kumar, Tr Santha, Henrich, Philipp P, Gagaring, Kerstin, Ibanez, Maureen, Kato, Nobutaka, Kuhen, Kelli L, Fischli, Christoph, Nagle, Advait, Rottmann, Matthias, Plouffe, David M, Bursulaya, Badry, Meister, Stephan, Rameh, Lucia, Trappe, Joerg, Haasen, Dorothea, Timmerman, Martijn, Sauerwein, Robert W, Suwanarusk, Rossarin, Russell, Bruce, Renia, Laurent, Nosten, Francois, Tully, David C, Kocken, Clemens Hm, Glynne, Richard J, Bodenreider, Christophe, Fidock, David A, Diagana, Thierry T, Winzeler, Elizabeth A
Published in Nature (London) (12.12.2013)
Published in Nature (London) (12.12.2013)
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Spiroindolones, a Potent Compound Class for the Treatment of Malaria
Rottmann, Matthias, McNamara, Case, Yeung, Bryan K.S, Lee, Marcus C.S, Zou, Bin, Russell, Bruce, Seitz, Patrick, Plouffe, David M, Dharia, Neekesh V, Tan, Jocelyn, Cohen, Steven B, Spencer, Kathryn R, González-Páez, Gonzalo E, Lakshminarayana, Suresh B, Goh, Anne, Suwanarusk, Rossarin, Jegla, Timothy, Schmitt, Esther K, Beck, Hans-Peter, Brun, Reto, Nosten, Francois, Renia, Laurent, Dartois, Veronique, Keller, Thomas H, Fidock, David A, Winzeler, Elizabeth A, Diagana, Thierry T
Published in Science (American Association for the Advancement of Science) (03.09.2010)
Published in Science (American Association for the Advancement of Science) (03.09.2010)
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PI4 Kinase Is a Prophylactic but Not Radical Curative Target in Plasmodium vivax-Type Malaria Parasites
Zeeman, Anne-Marie, Lakshminarayana, Suresh B, van der Werff, Nicole, Klooster, Els J, Voorberg-van der Wel, Annemarie, Kondreddi, Ravinder R, Bodenreider, Christophe, Simon, Oliver, Sauerwein, Robert, Yeung, Bryan K S, Diagana, Thierry T, Kocken, Clemens H M
Published in Antimicrobial agents and chemotherapy (01.05.2016)
Published in Antimicrobial agents and chemotherapy (01.05.2016)
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Pharmacokinetic-pharmacodynamic analysis of spiroindolone analogs and KAE609 in a murine malaria model
Lakshminarayana, Suresh B, Freymond, Céline, Fischli, Christoph, Yu, Jing, Weber, Sebastian, Goh, Anne, Yeung, Bryan K S, Ho, Paul C, Dartois, Véronique, Diagana, Thierry T, Rottmann, Matthias, Blasco, Francesca
Published in Antimicrobial agents and chemotherapy (01.02.2015)
Published in Antimicrobial agents and chemotherapy (01.02.2015)
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SPIRO-INDOLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES
YEUNG BRYAN KS, WONG WEI LIN JOSEPHINE, TAN LIYING JOCELYN, KRASTEL PHILIPP, ANG SHI HUA, LEONG SEH YONG, ZOU BIN
Year of Publication 24.12.2010
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Year of Publication 24.12.2010
Patent
Targeting Plasmodium phosphatidylinositol 4-kinase to eliminate malaria
McNamara, Case W, Lee, Marcus CS, Lim, Chek Shik, Lim, Siau Hoi, Roland, Jason, Simon, Oliver, Yeung, Bryan KS, Chatterjee, Arnab K, McCormack, Susan L, Manary, Micah J, Zeeman, Anne-Marie, Dechering, Koen J, Kumar, TR Santha, Henrich, Philipp P, Gagaring, Kerstin, Ibanez, Maureen, Kato, Nobutaka, Kuhen, Kelli L, Fischli, Christoph, Nagle, Advait, Rottmann, Matthias, Plouffe, David M, Bursulaya, Badry, Meister, Stephan, Rameh, Lucia, Trappe, Joerg, Haasen, Dorothea, Timmerman, Martijn, Sauerwein, Robert W, Suwanarusk, Rossarin, Russell, Bruce, Renia, Laurent, Nosten, Francois, Tully, David C, Kocken, Clemens HM, Glynne, Richard J, Bodenreider, Christophe, Fidock, David A, Diagana, Thierry T, Winzeler, Elizabeth A
Published in Nature (London) (27.11.2013)
Published in Nature (London) (27.11.2013)
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Journal Article
Na+ Regulation in the Malaria Parasite Plasmodiumfalciparum Involves the Cation ATPase PfATP4 and Is a Target of the Spiroindolone Antimalarials
Spillman, Natalie J, Allen, Richard JW, McNamara, Case W, Yeung, Bryan KS, Winzeler, Elizabeth A, Diagana, Thierry T, Kirk, Kiaran
Published in Cell host & microbe (13.02.2013)
Published in Cell host & microbe (13.02.2013)
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Preclinical Evaluation of the Antifolate QN254, 5-Chloro- N'6'-(2,5-Dimethoxy-Benzyl)-Quinazoline-2,4,6-Triamin e, as an Antimalarial Drug Candidate
Nzila, Alexis, Rottmann, Matthias, Chitnumsub, Penchit, Kiara, Stevens M, Kamchonwongpaisan, Sumalee, Maneeruttanarungroj, Cherdsak, Taweechai, Supannee, Yeung, Bryan KS, Goh, Anne, Lakshminarayana, Suresh B
Published in Antimicrobial agents and chemotherapy (01.06.2010)
Published in Antimicrobial agents and chemotherapy (01.06.2010)
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PROCESS TO MAKE N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 14.06.2023
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Year of Publication 14.06.2023
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PROCESS TO MAKE N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 26.04.2023
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Year of Publication 26.04.2023
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N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 11.01.2023
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Year of Publication 11.01.2023
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N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan Ks, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 07.06.2021
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Year of Publication 07.06.2021
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N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF
Yeo, Hui Quan, Wang, Gang, Yeung, Bryan KS, Yokokawa, Fumiaki, Zou, Bin, Kounde, Cyrille, Sim, Wei Lin Sandra, Simon, Oliver
Year of Publication 10.03.2022
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Year of Publication 10.03.2022
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N-substituted tetrahydrothienopyridine derivatives and uses thereof
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 24.02.2022
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Year of Publication 24.02.2022
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N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 28.04.2021
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Year of Publication 28.04.2021
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DÉRIVÉS DE TÉTRAHYDROTHIÉNOPYRIDINE N-SUBSTITUÉS ET LEURS UTILISATIONS
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 28.04.2021
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Year of Publication 28.04.2021
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N-substituted tetrahydrothienopyridine derivatives and uses thereof
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 04.02.2021
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Year of Publication 04.02.2021
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