Next generation sequencing of exceptional responders with BRAF-mutant melanoma: implications for sensitivity and resistance
Wheler, Jennifer, Yelensky, Roman, Falchook, Gerald, Kim, Kevin B, Hwu, Patrick, Tsimberidou, Apostolia M, Stephens, Philip J, Hong, David, Cronin, Maureen T, Kurzrock, Razelle
Published in BMC cancer (18.02.2015)
Published in BMC cancer (18.02.2015)
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Comprehensive genomic profiling (CGP) of advanced stage esophageal squamous cell carcinomas (ESCC) and esophageal adenocarcinomas (EAC) to reveal similarities and differences
Wang, Kai, Chmielecki, Juliann, Ali, Siraj M., Elvin, Julia Andrea, Yelensky, Roman, Lipson, Doron, Miller, Vincent A., Stephens, Philip J., Ross, Jeffrey S.
Published in Journal of clinical oncology (20.01.2015)
Published in Journal of clinical oncology (20.01.2015)
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Journal Article
Comprehensive genomic profiling (CGP) to assess mutational load in gastric and esophageal adenocarcinomas: Implications for immunotherapies
Frampton, Garrett Michael, Schrock, Alexa Betzig, Chalmers, Zachary Rockow, Sun, James, Ennis, Riley, Gowen, Kyle, Beg, Muhammad Shaalan, Rubinson, Douglas Adam, Yelensky, Roman, Stephens, Philip J, Miller, Vincent A., Ross, Jeffrey S., Ali, Siraj Mahamed, Klempner, Samuel Jacob
Published in Journal of clinical oncology (01.02.2016)
Published in Journal of clinical oncology (01.02.2016)
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Journal Article
Characterization of mutational load in patients with advanced urothelial cancer
Pal, Sumanta K., Ali, Siraj Mahamed, Ennis, Riley, Elvin, Julia Andrea, Vergilio, JoAnn, Suh, James, Yelensky, Roman, Ross, Jeffrey S., Miller, Vincent A., Joshi, Monika, Choueiri, Toni K., Stephens, Philip J., Frampton, Garrett Michael
Published in Journal of clinical oncology (10.01.2016)
Published in Journal of clinical oncology (10.01.2016)
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Journal Article
Genomic Alterations of Histone Modification Genes Are Significantly Less Common in Non-Hodgkin Lymphomas of Adolescents and Young Adults Compared to Older Patients
Wang, Kai, Morosini, Deborah, Yelensky, Roman, Palma, Norma, Johnson, Adrienne, Lipson, Doron, Chmielecki, Juliann, Ali, Siraj, Ross, Jeffrey S, Stephens, Philip J., Miller, Vincent
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
공유 항원을 표적으로 하는 항원-결합 단백질
RAINEY GODFREY JONAH ANDERSON, BLAIR WADE, BUSBY JENNIFER, YELENSKY ROMAN, BUSBY MICHELE ANNE, SKOBERNE MOJCA, JOOSS KARIN, GROTENBREG GIJSBERT MAMIX
Year of Publication 28.04.2021
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Year of Publication 28.04.2021
Patent
Presence of both alterations in FGFR/FGF and PI3K/AKT/mTOR confer improved outcomes for patients with metastatic breast cancer treated with PI3K/AKT/mTOR inhibitors
Wheler, Jennifer J, Atkins, Johnique T, Janku, Filip, Moulder, Stacy L, Stephens, Philip J, Yelensky, Roman, Valero, Vicente, Miller, Vincent, Kurzrock, Razelle, Meric-Bernstam, Funda
Published in Oncoscience (2016)
Published in Oncoscience (2016)
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Journal Article
Comprehensive Genomic Profiling (CGP) of Angioimmunoblastic T-Cell Lymphoma (AITL) to Prospectively Inform Diagnosis and Clinical Management
Morley, Samantha, He, Jie, Intlekofer, Andrew M., Bailey, Mark, Nahas, Michelle, Lipson, Doron, Yelensky, Roman, Ross, Jeffrey, Ali, Siraj, Erlich, Rachel, Stephens, Phil, Miller, Vincent A., Vergilio, Jo-Anne, Mughal, Tariq I
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Abstract A23: Comprehensive next-generation sequencing-based genomic profiling identifies actionable genomic alterations in diverse pediatric tumor types: The Foundation Medicine (FMI) experience
Hawryluk, Matthew J., Wang, Kai, Chmielecki, Juliann, Ali, Siraj M., Palmer, Gary, Garcia, Lazaro, White, Emily, Yelensky, Roman, Stephens, Philip J., Ross, Jeffrey S., Miller, Vincent A.
Published in Cancer research (Chicago, Ill.) (15.10.2014)
Published in Cancer research (Chicago, Ill.) (15.10.2014)
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Journal Article
METHODS AND SYSTEMS FOR EVALUATING TUMOR MUTATIONAL BURDEN
CONNELLY CAITLIN F, YELENSKY ROMAN, HEGDE PRITI, FABRIZIO DAVID, SUN JAMES XIN, CHALMERS ZACHARY R, FRAMPTON GARRETT MICHAEL, KOWANETZ MARCIN, STEPHENS PHILIP J
Year of Publication 15.02.2022
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Year of Publication 15.02.2022
Patent
Abstract 4268: An unbiased survey of cancer-related rearrangements in 5,917 solid tumors identifies therapeutically actionable fusions across multiple disease subtypes
Chmielecki, Juliann, Frampton, Garrett, Lipson, Doron, He, Jie, Otto, Geoff, Ali, Siraj, Ross, Jeffrey S., Miller, Vincent A., Yelensky, Roman, Stephens, Philip J.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
공유 항원
YELENSKY ROMAN, BUSBY JENNIFER, BLAIR WADE, BUSBY MICHELE, SUN JAMES XIN, SKOBERNE MOJCA, JOOSS KARIN, BULIK SULLIVAN BRENDAN
Year of Publication 03.02.2021
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Year of Publication 03.02.2021
Patent
Abstract 611: Exploratory analyses suggest ovarian tumors with somatic or germline loss of function mutations in BRCA1 or BRCA2 are biologically similar and sensitive to PARP inhibition
Dougherty, Brian, Lai, Zhongwu, Ledermann, Jonathan A., Robertson, Jane D., Ho, Tony W., Wu, Wenting, Hodgson, Darren R., Orr, Maria C M, O'Connor, Mark J., Hawryluk, Matthew J., Brennan, Timothy A., Yelensky, Roman, Sun, James X., Barrett, J Carl
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 1602: Development and validation of an NGS-based assay to detect all classes of genomic alterations in circulating tumor cells (CTCs) from patients with solid tumors
Welsh, Allison, Frampton, Garrett M., Chalmers, Zachary R., Sperger, Jamie, Yelensky, Roman, Lipson, Doron, Otto, Geoff, Strotman, Lindsay, Berry, Scott, Pezzi, Hannah, Traynor, Anne, Beebe, David J., Miller, Vincent A., Lang, Joshua M., Stephens, Philip J.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
An analysis of ERBB2 alterations (amplifications and mutations) found by next-generation sequencing (NGS) in 2000+ consecutive solid tumor (ST) patients
Palmer, Gary A., Wang, Kai, Miller, Vincent A., Yelensky, Roman, Stephens, Phil, Ross, Jeffrey S., Lipson, Doron
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Journal Article
THERAPEUTIC AND DIAGNOSTIC METHODS FOR CANCER
YELENSKY ROMAN, HEGDE PRITI, FABRIZIO DAVID, SUN JAMES XIN, FINE GREGG, BOURGON RICHARD, FRAMPTON GARRETT M, MARIATHASAN SANJEEV, STEPHENS PHILIP J
Year of Publication 14.10.2021
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Year of Publication 14.10.2021
Patent
Targeted next-generation sequencing (NGS) of carcinoma of unknown primary site (CUP): Actionable genomic alterations (GA) and new routes to targeted therapies
Ross, Jeffrey S., Wang, Kai, Otto, Geoff, Palmer, Gary A., Yelensky, Roman, Lipson, Doron, Chmielecki, Juliann, Ali, Siraj M., Morosini, Deborah, Miller, Vincent A., Stephens, Phil
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Therapeutic insights for malignant phyllodes from next-generation sequencing
Hirshfield, Kim M., Devries, Christiaan, Chojecki, Aleksander Lech, Ali, Siraj M., Yelensky, Roman, Chmielecki, Juliann, Ross, Jeffrey S., Stephens, Philip J., Miller, Vincent A., Rodriguez, Lorna, Ganesan, Shridar
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Comprehensive genomic profiling of solid tumors from 677 adolescents and young adults for revealing a distinct spectrum of targetable genomic alterations
Morosini, Deborah, Wang, Kai, Wagner, Klaus Wolfgang, Yelensky, Roman, Lipson, Doron, Chmielecki, Juliann, Ali, Siraj M., Ross, Jeffrey S., Stephens, Phil, Miller, Vincent A.
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article