Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thrombocytopenia and hemorrhage
Chao, Chiao-Hsuan, Wu, Wei-Chueh, Lai, Yen-Chung, Tsai, Pei-Jane, Perng, Guey-Chuen, Lin, Yee-Shin, Yeh, Trai-Ming
Published in PLoS pathogens (22.04.2019)
Published in PLoS pathogens (22.04.2019)
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Journal Article
Dengue virus non-structural protein 1: a pathogenic factor, therapeutic target, and vaccine candidate
Chen, Hong-Ru, Lai, Yen-Chung, Yeh, Trai-Ming
Published in Journal of biomedical science (24.07.2018)
Published in Journal of biomedical science (24.07.2018)
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Dengue virus-induced ER stress is required for autophagy activation, viral replication, and pathogenesis both in vitro and in vivo
Lee, Ying-Ray, Kuo, Szu-Han, Lin, Ching-Yen, Fu, Po-Jung, Lin, Yee-Shin, Yeh, Trai-Ming, Liu, Hsiao-Sheng
Published in Scientific reports (11.01.2018)
Published in Scientific reports (11.01.2018)
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Dengue Virus Nonstructural Protein 1 Induces Vascular Leakage through Macrophage Migration Inhibitory Factor and Autophagy
Chen, Hong-Ru, Chuang, Yung-Chun, Lin, Yee-Shin, Liu, Hsiao-Sheng, Liu, Ching-Chuan, Perng, Guey-Chuen, Yeh, Trai-Ming
Published in PLoS neglected tropical diseases (13.07.2016)
Published in PLoS neglected tropical diseases (13.07.2016)
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Macrophage migration inhibitory factor is critical for dengue NS1-induced endothelial glycocalyx degradation and hyperpermeability
Chen, Hong-Ru, Chao, Chiao-Hsuan, Liu, Ching-Chuan, Ho, Tzong-Shiann, Tsai, Huey-Pin, Perng, Guey-Chuen, Lin, Yee-Shin, Wang, Jen-Ren, Yeh, Trai-Ming
Published in PLoS pathogens (01.04.2018)
Published in PLoS pathogens (01.04.2018)
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Therapeutic efficacy of humanized monoclonal antibodies targeting dengue virus nonstructural protein 1 in the mouse model
Tien, Sen-Mao, Chang, Po-Chun, Lai, Yen-Chung, Chuang, Yung-Chun, Tseng, Chin-Kai, Kao, Yu-San, Huang, Hong-Jyun, Hsiao, Yu-Peng, Liu, Yi-Ling, Lin, Hsing-Han, Chu, Chien-Chou, Cheng, Miao-Huei, Ho, Tzong-Shiann, Chang, Chih-Peng, Ko, Shu-Fen, Shen, Che-Piao, Anderson, Robert, Lin, Yee-Shin, Wan, Shu-Wen, Yeh, Trai-Ming
Published in PLoS pathogens (01.04.2022)
Published in PLoS pathogens (01.04.2022)
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Negative regulation of type I interferon signaling by integrin-linked kinase permits dengue virus replication
Kao, Yi-Sheng, Wang, Li-Chiu, Chang, Po-Chun, Lin, Heng-Ming, Lin, Yee-Shin, Yu, Chia-Yi, Chen, Chien-Chin, Lin, Chiou-Feng, Yeh, Trai-Ming, Wan, Shu-Wen, Wang, Jen-Ren, Ho, Tzong-Shiann, Chu, Chien-Chou, Zhang, Bo-Cheng, Chang, Chih-Peng
Published in PLoS pathogens (01.03.2023)
Published in PLoS pathogens (01.03.2023)
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Journal Article
Dengue Nonstructural Protein 1 Maintains Autophagy through Retarding Caspase-Mediated Cleavage of Beclin-1
Lu, Zi-Yi, Cheng, Miao-Huei, Yu, Chia-Yi, Lin, Yee-Shin, Yeh, Trai-Ming, Chen, Chia-Ling, Chen, Chien-Chin, Wan, Shu-Wen, Chang, Chih-Peng
Published in International journal of molecular sciences (19.12.2020)
Published in International journal of molecular sciences (19.12.2020)
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Therapeutic Effects of Monoclonal Antibody against Dengue Virus NS1 in a STAT1 Knockout Mouse Model of Dengue Infection
Wan, Shu-Wen, Chen, Pei-Wei, Chen, Chin-Yu, Lai, Yen-Chung, Chu, Ya-Ting, Hung, Chia-Yi, Lee, Han, Wu, Hsuan Franziska, Chuang, Yung-Chun, Lin, Jessica, Chang, Chih-Peng, Wang, Shuying, Liu, Ching-Chuan, Ho, Tzong-Shiann, Lin, Chiou-Feng, Lee, Chien-Kuo, Wu-Hsieh, Betty A, Anderson, Robert, Yeh, Trai-Ming, Lin, Yee-Shin
Published in The Journal of immunology (1950) (15.10.2017)
Published in The Journal of immunology (1950) (15.10.2017)
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Antibodies against the SARS-CoV-2 S1-RBD cross-react with dengue virus and hinder dengue pathogenesis
Cheng, Yi-Ling, Chao, Chiao-Hsuan, Lai, Yen-Chung, Hsieh, Kun-Han, Wang, Jen-Ren, Wan, Shu-Wen, Huang, Hong-Jyun, Chuang, Yung-Chun, Chuang, Woei-Jer, Yeh, Trai-Ming
Published in Frontiers in immunology (15.08.2022)
Published in Frontiers in immunology (15.08.2022)
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Protection against dengue virus infection in mice by administration of antibodies against modified nonstructural protein 1
Wan, Shu-Wen, Lu, Yi-Tien, Huang, Chia-Hui, Lin, Chiou-Feng, Anderson, Robert, Liu, Hsiao-Sheng, Yeh, Trai-Ming, Yen, Yu-Ting, Wu-Hsieh, Betty A, Lin, Yee-Shin
Published in PloS one (21.03.2014)
Published in PloS one (21.03.2014)
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Autophagic machinery activated by dengue virus enhances virus replication
Lee, Ying-Ray, Lei, Huan-Yao, Liu, Ming-Tao, Wang, Jen-Ren, Chen, Shun-Hua, Jiang-Shieh, Ya-Fen, Lin, Yee-Shin, Yeh, Trai-Ming, Liu, Ching-Chuan, Liu, Hsiao-Sheng
Published in Virology (New York, N.Y.) (10.05.2008)
Published in Virology (New York, N.Y.) (10.05.2008)
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Enhancement of NETosis by ACE2-cross-reactive anti-SARS-CoV-2 RBD antibodies in patients with COVID-19
Hsieh, Kun-Han, Chao, Chiao-Hsuan, Cheng, Yi-Ling, Lai, Yen-Chung, Chuang, Yung-Chun, Wang, Jen-Ren, Chang, Sui-Yuan, Hung, Yuan-Pin, Chen, Yi-Ming Arthur, Liu, Wei-Lun, Chuang, Woei-Jer, Yeh, Trai-Ming
Published in Journal of biomedical science (18.04.2024)
Published in Journal of biomedical science (18.04.2024)
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Antigenic Cross-Reactivity Between SARS-CoV-2 S1-RBD and Its Receptor ACE2
Lai, Yen-Chung, Cheng, Yu-Wei, Chao, Chiao-Hsuan, Chang, Yu-Ying, Chen, Chi-De, Tsai, Wei-Jiun, Wang, Shuying, Lin, Yee-Shin, Chang, Chih-Peng, Chuang, Woei-Jer, Chen, Li-Yin, Wang, Ying-Ren, Chang, Sui-Yuan, Huang, Wenya, Wang, Jen-Ren, Tseng, Chin-Kai, Lin, Chun-Kuang, Chuang, Yung-Chun, Yeh, Trai-Ming
Published in Frontiers in immunology (04.05.2022)
Published in Frontiers in immunology (04.05.2022)
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Molecular mimicry between virus and host and its implications for dengue disease pathogenesis
Lin, Yee-Shin, Yeh, Trai-Ming, Lin, Chiou-Feng, Wan, Shu-Wen, Chuang, Yung-Chun, Hsu, Tan-Kuei, Liu, Hsiao-Sheng, Liu, Ching-Chuan, Anderson, Robert, Lei, Huan-Yao
Published in Experimental biology and medicine (Maywood, N.J.) (01.05.2011)
Published in Experimental biology and medicine (Maywood, N.J.) (01.05.2011)
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Macrophage migration inhibitory factor induces autophagy via reactive oxygen species generation
Chuang, Yung-Chun, Su, Wen-Hong, Lei, Huan-Yao, Lin, Yee-Shin, Liu, Hsiao-Sheng, Chang, Chih-Peng, Yeh, Trai-Ming
Published in PloS one (22.05.2012)
Published in PloS one (22.05.2012)
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Journal Article
Pathogenic Roles of Macrophage Migration Inhibitory Factor during Dengue Virus Infection
Chuang, Yung-Chun, Yeh, Trai-Ming, Chen, Hong-Ru
Published in Mediators of Inflammation (01.01.2015)
Published in Mediators of Inflammation (01.01.2015)
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