Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme
Wallace, Bret D, Wang, Hongwei, Lane, Kimberly T, Scott, John E, Orans, Jillian, Koo, Ja Seol, Venkatesh, Madhukumar, Jobin, Christian, Yeh, Li-An, Mani, Sridhar, Redinbo, Matthew R
Published in Science (American Association for the Advancement of Science) (05.11.2010)
Published in Science (American Association for the Advancement of Science) (05.11.2010)
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Small-molecule activators of insulin-degrading enzyme discovered through high-throughput compound screening
Cabrol, Christelle, Huzarska, Malwina A, Dinolfo, Christopher, Rodriguez, Maria C, Reinstatler, Lael, Ni, Jake, Yeh, Li-An, Cuny, Gregory D, Stein, Ross L, Selkoe, Dennis J, Leissring, Malcolm A
Published in PloS one (22.04.2009)
Published in PloS one (22.04.2009)
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Inhibitors of RecA Activity Discovered by High-Throughput Screening: Cell-Permeable Small Molecules Attenuate the SOS Response in Escherichia coli
Wigle, Tim J., Sexton, Jonathan Z., Gromova, Anna V., Hadimani, Mallinath B., Hughes, Mark A., Smith, Ginger R., Yeh, Li-An, Singleton, Scott F.
Published in Journal of biomolecular screening (01.10.2009)
Published in Journal of biomolecular screening (01.10.2009)
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Old Drug New Use―Amoxapine and Its Metabolites as Potent Bacterial β-Glucuronidase Inhibitors for Alleviating Cancer Drug Toxicity
REN KONG, LIU, Timothy, XIAOPING ZHU, AHMAD, Syed, WILLIAMS, Alfred L, PHAN, Alexandria T, HONG ZHAO, SCOTT, John E, YEH, Li-An, WONG, Stephen T. C
Published in Clinical cancer research (01.07.2014)
Published in Clinical cancer research (01.07.2014)
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Potential repurposing of known drugs as potent bacterial β-glucuronidase inhibitors
Ahmad, Syed, Hughes, Mark A, Yeh, Li-An, Scott, John E
Published in Journal of biomolecular screening (01.08.2012)
Published in Journal of biomolecular screening (01.08.2012)
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Journal Article
Two approaches to drug discovery in SOD1-mediated ALS
Broom, Wendy J, Auwarter, Kristen E, Ni, Jake, Russel, Deborah E, Yeh, Li-An, Maxwell, Michele M, Glicksman, Marcie, Kazantsev, Aleksey G, Brown, Jr, Robert H
Published in Journal of biomolecular screening (01.10.2006)
Published in Journal of biomolecular screening (01.10.2006)
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Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS) is expressed at high yield as an active homotetramer in baculovirus-infected insect cells
Lamson, David R., House, Alan J., Danshina, Polina V., Sexton, Jonathan Z., Sanyang, Khaddijatou, O’Brien, Deborah A., Yeh, Li-An, Williams, Kevin P.
Published in Protein expression and purification (01.01.2011)
Published in Protein expression and purification (01.01.2011)
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Synthesis, stereochemistry confirmation and biological activity evaluation of a constituent from Isodon excisus
Xing, Xuechao, Ho, Pei, Bourquin, Geoffroy, Yeh, Li-An, Cuny, Gregory D
Published in Tetrahedron (08.12.2003)
Published in Tetrahedron (08.12.2003)
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Identifying druglike inhibitors of myelin-reactive T cells by phenotypic high-throughput screening of a small-molecule library
Rossi, Christina, Padmanaban, Deepa, Ni, Jake, Yeh, Li-An, Glicksman, Marcie A, Waldner, Hanspeter
Published in Journal of biomolecular screening (01.06.2007)
Published in Journal of biomolecular screening (01.06.2007)
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Homogeneous time-resolved fluorescence resonance energy transfer assay for measurement of Phox/Bem1p (PB1) domain heterodimerization
Nakamura, Kazuhiro, Zawistowski, Jon S, Hughes, Mark A, Sexton, Jonathan Z, Yeh, Li-An, Johnson, Gary L, Scott, John E
Published in Journal of biomolecular screening (01.06.2008)
Published in Journal of biomolecular screening (01.06.2008)
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A High-Throughput Screen to Identify Inhibitors of Amyloid β-Protein Precursor Processing
Bakshi, Pancham, Liao, Yung-Feng, Gao, Jun, Ni, Jake, Stein, Ross, Yeh, Li-An, Wolfe, Michael S.
Published in Journal of biomolecular screening (01.02.2005)
Published in Journal of biomolecular screening (01.02.2005)
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Effects of a verbenachalcone derivative on neurite outgrowth, inhibition of caspase induction and gene expression
Yeh, Li-An, Padmanaban, Deppa, Ho, Pei, Xing, Xeuchao, Rowley, Patricia, Morse, Lee Jae, Jensen, Roderick V., Cuny, Gregory D.
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
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Development of an assay to screen for inhibitors of tau phosphorylation by cdk5
Ahn, Jae Suk, Musacchio, Andrea, Mapelli, Marina, Ni, Jake, Scinto, Leonard, Stein, Ross, Kosik, Kenneth S, Yeh, Li-An
Published in Journal of biomolecular screening (01.03.2004)
Published in Journal of biomolecular screening (01.03.2004)
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Discovery of compounds that will prevent tau pathology
Kosik, Kenneth S, Ahn, Jae, Stein, Ross, Yeh, Li-An
Published in Journal of molecular neuroscience (01.12.2002)
Published in Journal of molecular neuroscience (01.12.2002)
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Development of a fluorescent high throughput assay for tau aggregation
Liu, Min, Ni, Jake, Kosik, Kenneth S, Yeh, Li-An
Published in Assay and drug development technologies (01.12.2004)
Published in Assay and drug development technologies (01.12.2004)
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Discovery of Inhibitors that Elucidate the Role of UCH-L1 Activity in the H1299 Lung Cancer Cell Line
Liu, Yichin, Lashuel, Hilal A., Choi, Sungwoon, Xing, Xuechao, Case, April, Ni, Jake, Yeh, Li-An, Cuny, Gregory D., Stein, Ross L., Lansbury, Peter T.
Published in Chemistry & biology (01.09.2003)
Published in Chemistry & biology (01.09.2003)
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