Validation of Diacyl Glycerolacyltransferase I as a Novel Target for the Treatment of Obesity and Dyslipidemia Using a Potent and Selective Small Molecule Inhibitor
Zhao, Gang, Souers, Andrew J, Voorbach, Martin, Falls, H. Doug, Droz, Brian, Brodjian, Sevan, Lau, Yau Yi, Iyengar, Rajesh R, Gao, Ju, Judd, Andrew S, Wagaw, Seble H, Ravn, Matthew M, Engstrom, Kenneth M, Lynch, John K, Mulhern, Mathew M, Freeman, Jennifer, Dayton, Brian D, Wang, Xiaojun, Grihalde, Nelson, Fry, Dennis, Beno, David W. A, Marsh, Kennan C, Su, Zhi, Diaz, Gilbert J, Collins, Christine A, Sham, Hing, Reilly, Regina M, Brune, Michael E, Kym, Philip R
Published in Journal of medicinal chemistry (14.02.2008)
Published in Journal of medicinal chemistry (14.02.2008)
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Semi-automatic high-throughput determination of plasma protein binding using a 96-well plate filtrate assembly and fast liquid chromatography–tandem mass spectrometry
Fung, Eliza N, Chen, Yung-Hsiang, Lau, Yau Yi
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.10.2003)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.10.2003)
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Journal Article
Characterization of glucose microsensors for intracellular measurements
Abe, Takayuki, Lau, Yau Yi, Ewing, Andrew G
Published in Analytical chemistry (Washington) (15.09.1992)
Published in Analytical chemistry (Washington) (15.09.1992)
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Journal Article
Pulse voltammetry in single cells using platinum microelectrodes
Chen, Ta Kung, Lau, Yau Yi, Wong, Danny K. Y, Ewing, Andrew G
Published in Analytical chemistry (Washington) (01.06.1992)
Published in Analytical chemistry (Washington) (01.06.1992)
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Journal Article
Rapid hit to lead evaluation of pyrazolo[3,4- d]pyrimidin-4-one as selective and orally bioavailable mGluR1 antagonists
Wang, Xueqing, Kolasa, Teodozyi, El Kouhen, Odile F., Chovan, Linda E., Black-Shaefer, Candace L., Wagenaar, Frank L., Garton, Jennifer A., Moreland, Robert B., Honore, Prisca, Lau, Yau Yi, Dandliker, Peter J., Brioni, Jorge D., Stewart, Andrew O.
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
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Analytical chemistry in microenvironments: single nerve cells
Ewing, Andrew G, Strein, Timothy G, Lau, Yau Yi
Published in Accounts of chemical research (01.10.1992)
Published in Accounts of chemical research (01.10.1992)
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Voltammetric measurement of oxygen in single neurons using platinized carbon ring electrodes
Lau, Yau Yi, Abe, Takayuki, Ewing, Andrew G
Published in Analytical chemistry (Washington) (01.08.1992)
Published in Analytical chemistry (Washington) (01.08.1992)
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Determination of pramipexole (U-98,528) in human plasma by high-performance liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry
Yau, Yi Lau, Selenka, Jeffrey M., Hanson, Glenn D., Talaat, Rasmy, Ichhpurani, Nita
Published in Journal of chromatography. B, Biomedical applications (30.08.1996)
Published in Journal of chromatography. B, Biomedical applications (30.08.1996)
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Determination of pramipexole (U-98,528) in human plasma and urine by high-performance liquid chromatography with electrochemical and ultraviolet detection
Yau, Yi Lau, Hanson, Glenn D., Ichhpurani, Nita
Published in Journal of chromatography. B, Biomedical applications (30.08.1996)
Published in Journal of chromatography. B, Biomedical applications (30.08.1996)
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Journal Article
Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport
Sulzer, D, Chen, TK, Lau, YY, Kristensen, H, Rayport, S, Ewing, A
Published in The Journal of neuroscience (01.05.1995)
Published in The Journal of neuroscience (01.05.1995)
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Journal Article
Semi-automated determination of plasma stability of drug discovery compounds using liquid chromatography–tandem mass spectrometry
Wang, Gangfeng, Hsieh, Yunsheng, Lau, YauYi, Cheng, K.-C, Ng, Kwokei, Korfmacher, Walter A, White, Ronald E
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (25.11.2002)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (25.11.2002)
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A high-throughput cell-based reporter gene system for measurement of CYP1A1 induction
Cui, Xiaoming, Palamanda, Jairam, Norton, Laura, Thomas, Ann, Lau, Yau Yi, White, Ronald E., Cheng, K.-C.
Published in Journal of pharmacological and toxicological methods (01.05.2002)
Published in Journal of pharmacological and toxicological methods (01.05.2002)
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The use of in vitro metabolic stability for rapid selection of compounds in early discovery based on their expected hepatic extraction ratios
YAU YI LAU, KRISHNA, Gopal, YUMIBE, Nathan P, GROTZ, Diane E, SAPIDOU, Elpida, NORTON, Laura, INHOU CHU, CHEN, Cliff, SOARES, A. D, LIN, Chin-Chung
Published in Pharmaceutical research (01.11.2002)
Published in Pharmaceutical research (01.11.2002)
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