Indazole-Based Potent and Cell-Active Mps1 Kinase Inhibitors: Rational Design from Pan-Kinase Inhibitor Anthrapyrazolone (SP600125)
Kusakabe, Ken-ichi, Ide, Nobuyuki, Daigo, Yataro, Tachibana, Yuki, Itoh, Takeshi, Yamamoto, Takahiko, Hashizume, Hiroshi, Hato, Yoshio, Higashino, Kenichi, Okano, Yousuke, Sato, Yuji, Inoue, Makiko, Iguchi, Motofumi, Kanazawa, Takayuki, Ishioka, Yukichi, Dohi, Keiji, Kido, Yasuto, Sakamoto, Shingo, Yasuo, Kazuya, Maeda, Masahiro, Higaki, Masayo, Ueda, Kazuo, Yoshizawa, Hidenori, Baba, Yoshiyasu, Shiota, Takeshi, Murai, Hitoshi, Nakamura, Yusuke
Published in Journal of medicinal chemistry (13.06.2013)
Published in Journal of medicinal chemistry (13.06.2013)
Get full text
Journal Article
Diaminopyridine-Based Potent and Selective Mps1 Kinase Inhibitors Binding to an Unusual Flipped-Peptide Conformation
Kusakabe, Ken-ichi, Ide, Nobuyuki, Daigo, Yataro, Itoh, Takeshi, Higashino, Kenichi, Okano, Yousuke, Tadano, Genta, Tachibana, Yuki, Sato, Yuji, Inoue, Makiko, Wada, Tooru, Iguchi, Motofumi, Kanazawa, Takayuki, Ishioka, Yukichi, Dohi, Keiji, Tagashira, Sachie, Kido, Yasuto, Sakamoto, Shingo, Yasuo, Kazuya, Maeda, Masahiro, Yamamoto, Takahiko, Higaki, Masayo, Endoh, Takeshi, Ueda, Kazuo, Shiota, Takeshi, Murai, Hitoshi, Nakamura, Yusuke
Published in ACS medicinal chemistry letters (12.07.2012)
Published in ACS medicinal chemistry letters (12.07.2012)
Get full text
Journal Article
Dual 5‑HT2A and 5‑HT2C Receptor Inverse Agonist That Affords In Vivo Antipsychotic Efficacy with Minimal hERG Inhibition for the Treatment of Dementia-Related Psychosis
Oguma, Takuya, Jino, Kohei, Nakahara, Kenji, Asada, Hidetsugu, Fuchino, Kouki, Nagatani, Kotaro, Kouki, Kensuke, Okamoto, Ryuji, Takai, Nozomi, Koda, Ken, Fujita, Sayaka, Sekiguchi, Yusuke, Yasuo, Kazuya, Mayumi, Kei, Abe, Ayane, Imono, Masaaki, Horiguchi, Naotaka, Iwata, So, Kusakabe, Ken-ichi
Published in Journal of medicinal chemistry (22.08.2024)
Published in Journal of medicinal chemistry (22.08.2024)
Get full text
Journal Article
Dual 5-HT 2A and 5-HT 2C Receptor Inverse Agonist That Affords In Vivo Antipsychotic Efficacy with Minimal hERG Inhibition for the Treatment of Dementia-Related Psychosis
Oguma, Takuya, Jino, Kohei, Nakahara, Kenji, Asada, Hidetsugu, Fuchino, Kouki, Nagatani, Kotaro, Kouki, Kensuke, Okamoto, Ryuji, Takai, Nozomi, Koda, Ken, Fujita, Sayaka, Sekiguchi, Yusuke, Yasuo, Kazuya, Mayumi, Kei, Abe, Ayane, Imono, Masaaki, Horiguchi, Naotaka, Iwata, So, Kusakabe, Ken-Ichi
Published in Journal of medicinal chemistry (22.08.2024)
Published in Journal of medicinal chemistry (22.08.2024)
Get full text
Journal Article
Synthesis and SAR Study of Carbamoyl Pyridone Bicycle Derivatives as Potent Inhibitors of Influenza Cap-dependent Endonuclease
Miyagawa, Masayoshi, Akiyama, Toshiyuki, Taoda, Yoshiyuki, Takaya, Kenji, Takahashi-Kageyama, Chika, Tomita, Kenji, Yasuo, Kazuya, Hattori, Kazunari, Shano, Shinya, Yoshida, Ryu, Shishido, Takao, Yoshinaga, Tomokazu, Sato, Akihiko, Kawai, Makoto
Published in Journal of medicinal chemistry (12.09.2019)
Published in Journal of medicinal chemistry (12.09.2019)
Get full text
Journal Article
HETEROCYCLE DERIVATIVE WITH HIV REPLICATION INHIBITORY ACTION
KUSUI YOSHIFUMI, OKANO AZUSA, TADANO GENTA, HORIGUCHI TORU, YASUO KAZUYA
Year of Publication 13.03.2024
Get full text
Year of Publication 13.03.2024
Patent
A novel tricyclic β-lactam exhibiting potent antibacterial activities against carbapenem-resistant Enterobacterales: Synthesis and structure-activity-relationships
Sato, Jun, Kusano, Hiroki, Aoki, Toshiaki, Shibuya, Satoru, Yokoo, Katsuki, Komano, Kazuo, Oguma, Takuya, Matsumoto, Shuhei, Sato, Takafumi, Yasuo, Kazuya, Yamawaki, Kenji
Published in Bioorganic & medicinal chemistry (15.09.2021)
Published in Bioorganic & medicinal chemistry (15.09.2021)
Get full text
Journal Article
FUSED HETEROCYCLIC DERIVATIVE HAVING HIV REPLICATION INHIBITORY ACTION
KUSUMOTO Yoshifumi, MASAKADO Sota, YASUO Kazuya, OKANO Azusa, TADANO Genta
Year of Publication 09.03.2023
Get full text
Year of Publication 09.03.2023
Patent
FUSED HETEROCYCLE HAVING TRKA INHIBITORY ACTIVITY AND FUSED CARBOCYCLE DERIVATIVE
YASUO, Kazuya, HORIGUCHI, Tohru, YAMAGUCHI, Hiroki, HATA, Kayoko, KANO, Kazuya
Year of Publication 03.05.2018
Get full text
Year of Publication 03.05.2018
Patent
Fused heterocyclic derivative having HIV replication inhibitory activity
TADANO, GENTA, MASAKADO, SOTA, KUSUMOTO, YOSHIFUMI, YASUO, KAZUYA, OKANO, AZUSA
Year of Publication 01.05.2023
Get full text
Year of Publication 01.05.2023
Patent
BELT CONVEYOR DEVICE
TAKAGI MASANOBU, YASUO KAZUYA, TANAKA KIICHIROU, SHIGA TAKAKAZU, FUJISAWA KAORU
Year of Publication 29.11.1994
Get full text
Year of Publication 29.11.1994
Patent
Controller for hybrid car
MATSUBARA A.,SHIBUTANI A.,WAKASHIRO T.,KAYANO MORIO,NAKAMOTO YASUO,OZONO KAZUYA
Year of Publication 27.12.2006
Get full text
Year of Publication 27.12.2006
Patent
Reciprocating compressor
NISHIKAWA TAKAHIRO,NISHIKAWA HIROSHI,HARAKO TAKASHI,MIZUNO TAKAYUKI,SATO KAZUYA,SAKAMOTO YASUO
Year of Publication 19.07.2006
Get full text
Year of Publication 19.07.2006
Patent
Reciprocating compressor
NISHIKAWA TAKAHIRO,NISHIKAWA HIROSHI,HARAKO TAKASHI,MIZUNO TAKAYUKI,SATO KAZUYA,SAKAMOTO YASUO
Year of Publication 19.07.2006
Get full text
Year of Publication 19.07.2006
Patent