RNA-Guided Human Genome Engineering via Cas9
Mali, Prashant, Yang, Luhan, Esvelt, Kevin M., Aach, John, Guell, Marc, DiCarlo, James E., Norville, Julie E., Church, George M.
Published in Science (American Association for the Advancement of Science) (15.02.2013)
Published in Science (American Association for the Advancement of Science) (15.02.2013)
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Journal Article
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Mali, Prashant, Aach, John, Stranges, P Benjamin, Esvelt, Kevin M, Moosburner, Mark, Kosuri, Sriram, Yang, Luhan, Church, George M
Published in Nature biotechnology (01.09.2013)
Published in Nature biotechnology (01.09.2013)
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Journal Article
Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA)
Güell, Marc, Yang, Luhan, Church, George M
Published in Bioinformatics (Oxford, England) (15.10.2014)
Published in Bioinformatics (Oxford, England) (15.10.2014)
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Journal Article
Error-prone meiotic division and subfertility in mice with oocyte-conditional knockdown of pericentrin
Baumann, Claudia, Wang, Xiaotian, Yang, Luhan, Viveiros, Maria M
Published in Journal of cell science (01.04.2017)
Published in Journal of cell science (01.04.2017)
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Journal Article
Genome-wide inactivation of porcine endogenous retroviruses (PERVs)
Yang, Luhan, Güell, Marc, Niu, Dong, George, Haydy, Lesha, Emal, Grishin, Dennis, Aach, John, Shrock, Ellen, Xu, Weihong, Poci, Jürgen, Cortazio, Rebeca, Wilkinson, Robert A., Fishman, Jay A., Church, George
Published in Science (American Association for the Advancement of Science) (27.11.2015)
Published in Science (American Association for the Advancement of Science) (27.11.2015)
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Journal Article
Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9
Niu, Dong, Wei, Hong-Jiang, Lin, Lin, George, Haydy, Wang, Tao, Lee, I-Hsiu, Zhao, Hong-Ye, Wang, Yong, Kan, Yinan, Shrock, Ellen, Lesha, Emal, Wang, Gang, Luo, Yonglun, Qing, Yubo, Jiao, Deling, Zhao, Heng, Zhou, Xiaoyang, Wang, Shouqi, Wei, Hong, Güell, Marc, Church, George M., Yang, Luhan
Published in Science (American Association for the Advancement of Science) (22.09.2017)
Published in Science (American Association for the Advancement of Science) (22.09.2017)
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Journal Article
Artificial intelligence and database technology work together
Wang, Xinyi, Zhang, Liyu, Yang, Luhan
Published in Journal of physics. Conference series (01.06.2021)
Published in Journal of physics. Conference series (01.06.2021)
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Journal Article
Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
Hinson, John T., Chopra, Anant, Nafissi, Navid, Polacheck, William J., Benson, Craig C., Swist, Sandra, Gorham, Joshua, Yang, Luhan, Schafer, Sebastian, Sheng, Calvin C., Haghighi, Alireza, Homsy, Jason, Hubner, Norbert, Church, George, Cook, Stuart A., Linke, Wolfgang A., Chen, Christopher S., Seidman, J. G., Seidman, Christine E.
Published in Science (American Association for the Advancement of Science) (28.08.2015)
Published in Science (American Association for the Advancement of Science) (28.08.2015)
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Journal Article
Optimization of scarless human stem cell genome editing
Yang, Luhan, Guell, Marc, Byrne, Susan, Yang, Joyce L, De Los Angeles, Alejandro, Mali, Prashant, Aach, John, Kim-Kiselak, Caroline, Briggs, Adrian W, Rios, Xavier, Huang, Po-Yi, Daley, George, Church, George
Published in Nucleic acids research (01.10.2013)
Published in Nucleic acids research (01.10.2013)
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Journal Article
Kidney transplantation from triple‐knockout pigs expressing multiple human proteins in cynomolgus macaques
Ma, David, Hirose, Takayuki, Lassiter, Grace, Sasaki, Hajime, Rosales, Ivy, Coe, Taylor M., Rickert, Charles G., Matheson, Rudy, Colvin, Robert B., Qin, Wenning, Kan, Yinan, Layer, Jacob V., Paragas, Violette B., Stiede, Kathryn, Hall, Katherine C., Youd, Michele E., Queiroz, Luis M., Westlin, William F., Curtis, Michael, Yang, Luhan, Markmann, James F., Kawai, Tatsuo
Published in American journal of transplantation (01.01.2022)
Published in American journal of transplantation (01.01.2022)
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Journal Article
Efficient, footprint-free human iPSC genome editing by consolidation of Cas9/CRISPR and piggyBac technologies
Wang, Gang, Yang, Luhan, Grishin, Dennis, Rios, Xavier, Ye, Lillian Y, Hu, Yong, Li, Kai, Zhang, Donghui, Church, George M, Pu, William T
Published in Nature protocols (01.01.2017)
Published in Nature protocols (01.01.2017)
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Journal Article
The Genome Project–Write
Boeke, Jef D., Church, George, Hessel, Andrew, Kelley, Nancy J., Arkin, Adam, Cai, Yizhi, Carlson, Rob, Chakravarti, Aravinda, Cornish, Virginia W., Holt, Liam, Isaacs, Farren J., Kuiken, Todd, Lajoie, Marc, Lessor, Tracy, Lunshof, Jeantine, Maurano, Matthew T., Mitchell, Leslie A., Rine, Jasper, Rosser, Susan, Sanjana, Neville E., Silver, Pamela A., Valle, David, Wang, Harris, Way, Jeffrey C., Yang, Luhan
Published in Science (American Association for the Advancement of Science) (08.07.2016)
Published in Science (American Association for the Advancement of Science) (08.07.2016)
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Journal Article
Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells
Yang, Luhan, Grishin, Dennis, Wang, Gang, Aach, John, Zhang, Cheng-Zhong, Chari, Raj, Homsy, Jason, Cai, Xuyu, Zhao, Yue, Fan, Jian-Bing, Seidman, Christine, Seidman, Jonathan, Pu, William, Church, George
Published in Nature communications (26.11.2014)
Published in Nature communications (26.11.2014)
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Journal Article
Engineering and optimising deaminase fusions for genome editing
Yang, Luhan, Briggs, Adrian W., Chew, Wei Leong, Mali, Prashant, Guell, Marc, Aach, John, Goodman, Daniel Bryan, Cox, David, Kan, Yinan, Lesha, Emal, Soundararajan, Venkataramanan, Zhang, Feng, Church, George
Published in Nature communications (02.11.2016)
Published in Nature communications (02.11.2016)
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Journal Article
Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells
Odorico, Jon, Markmann, James, Melton, Douglas, Greenstein, Julia, Hwa, Albert, Nostro, Cristina, Rezania, Alireza, Oberholzer, Jose, Pipeleers, Daniel, Yang, Luhan, Cowan, Chad, Huangfu, Danwei, Egli, Dieter, Ben-David, Uri, Vallier, Ludovic, Grey, Shane T, Tang, Qizhi, Roep, Bart, Ricordi, Camilo, Naji, Ali, Orlando, Giuseppe, Anderson, Daniel G, Poznansky, Mark, Ludwig, Barbara, Tomei, Alice, Greiner, Dale L, Graham, Melanie, Carpenter, Melissa, Migliaccio, Giovanni, D'Amour, Kevin, Hering, Bernhard, Piemonti, Lorenzo, Berney, Thierry, Rickels, Mike, Kay, Thomas, Adams, Ann
Published in Transplantation (01.08.2018)
Published in Transplantation (01.08.2018)
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Journal Article
Research progress of mitochondrial dysfunction induced pyroptosis in acute lung injury
Yang, Luhan, Ren, Qingyi, Wang, Yaohui, Zheng, Yucheng, Du, Fei, Wang, Fang, Zhou, Jie, Gui, Linxi, Chen, Shengdong, Chen, Xiurui, Zhang, Wanting, Sun, Yuhong, Zhong, Xiaolin, Liu, Hao, Jiang, Xian, Zhang, Zhuo
Published in Respiratory research (07.11.2024)
Published in Respiratory research (07.11.2024)
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Journal Article
Extensive germline genome engineering in pigs
Yue, Yanan, Xu, Weihong, Kan, Yinan, Zhao, Hong-Ye, Zhou, Yixuan, Song, Xiaobin, Wu, Jiajia, Xiong, Juan, Goswami, Dharmendra, Yang, Meng, Lamriben, Lydia, Xu, Mengyuan, Zhang, Qi, Luo, Yu, Guo, Jianxiong, Mao, Shengyi, Jiao, Deling, Nguyen, Tien Dat, Li, Zhuo, Layer, Jacob V., Li, Mailin, Paragas, Violette, Youd, Michele E., Sun, Zhongquan, Ding, Yuan, Wang, Weilin, Dou, Hongwei, Song, Lingling, Wang, Xueqiong, Le, Lei, Fang, Xin, George, Haydy, Anand, Ranjith, Wang, Shi Yun, Westlin, William F., Güell, Marc, Markmann, James, Qin, Wenning, Gao, Yangbin, Wei, Hong-Jiang, Church, George M., Yang, Luhan
Published in Nature biomedical engineering (01.02.2021)
Published in Nature biomedical engineering (01.02.2021)
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