Dose optimization of TBI-223 for enhanced therapeutic benefit compared to linezolid in antituberculosis regimen
Strydom, Natasha, Ernest, Jacqueline P, Imperial, Marjorie, Solans, Belén P, Wang, Qianwen, Tasneen, Rokeya, Tyagi, Sandeep, Soni, Heena, Garcia, Andrew, Bigelow, Kristina, Gengenbacher, Martin, Zimmerman, Matthew, Xie, Min, Sarathy, Jansy P, Yang, Tian J, Dartois, Véronique, Nuermberger, Eric L, Savic, Radojka M
Published in Nature communications (25.08.2024)
Published in Nature communications (25.08.2024)
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The Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of America
GRIMM, Scott W, EINOLF, Heidi J, TONN, George R, VAN HORN, Robert, WANG, Regina W, WONG, Y. Nancy, YANG, Tian J, OBACH, R. Scott, HALL, Steven D, KAN HE, LIM, Heng-Keang, LING, Kah-Hiing John, CHUANG LU, NOMEIR, Amin A, SEIBERT, Eleanore, SKORDOS, Konstantine W
Published in Drug metabolism and disposition (01.07.2009)
Published in Drug metabolism and disposition (01.07.2009)
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Toxicity and toxicokinetic assessment of an anti-tubercular drug pretomanid in cynomolgus monkeys
Bruning-Barry, Rebecca, Ambroso, Jeffrey L., Dillberger, John, Yang, Tian J.
Published in Toxicology reports (01.01.2022)
Published in Toxicology reports (01.01.2022)
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Journal Article
Advancing the Therapeutic Potential of Indoleamides for Tuberculosis
Lun, Shichun, Tasneen, Rokeya, Chaira, Tridib, Stec, Jozef, Onajole, Oluseye K, Yang, Tian J, Cooper, Christopher B, Mdluli, Khisi, Converse, Paul J, Nuermberger, Eric L, Raj, V Samuel, Kozikowski, Alan, Bishai, William R
Published in Antimicrobial agents and chemotherapy (01.07.2019)
Published in Antimicrobial agents and chemotherapy (01.07.2019)
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CONCURRENT INDUCTION AND MECHANISM-BASED INACTIVATION OF CYP3A4 BY AN l-VALINAMIDE DERIVATIVE
Luo, Gang, Lin, Jianrong, Fiske, William D, Dai, Renke, Yang, Tian J, Kim, Sean, Sinz, Michael, LeCluyse, Edward, Solon, Eric, Brennan, James M, Benedek, Irma H, Jolley, Summer, Gilbert, Darryl, Wang, Lifei, Lee, Frank W, Gan, Liang-Shang
Published in Drug metabolism and disposition (01.09.2003)
Published in Drug metabolism and disposition (01.09.2003)
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Phase 1 Study of the Effects of the Tuberculosis Treatment Pretomanid, Alone and in Combination With Moxifloxacin, on the QTc Interval in Healthy Volunteers
Li, Mengchun, Saviolakis, George A., El‐Amin, Wael, Makhene, Mamodikoe K., Osborn, Blaire, Nedelman, Jerry, Yang, Tian J., Everitt, Daniel
Published in Clinical pharmacology in drug development (01.06.2021)
Published in Clinical pharmacology in drug development (01.06.2021)
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Journal Article
Role of cDNA-Expressed Human Cytochromes P450 in the Metabolism of Diazepam
Yang, Tian J, Shou, Magang, Korzekwa, Kenneth R, Gonzalez, Frank J, Gelboin, Harry V, Yang, Shen K
Published in Biochemical pharmacology (15.03.1998)
Published in Biochemical pharmacology (15.03.1998)
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Interaction of Ritonavir on Tissue Distribution of a [14C]L-Valinamide, a Potent Human Immunodeficiency Virus-1 Protease Inhibitor, in Rats Using Quantitative Whole-Body Autoradiography
SOLON, Eric G, BALANI, Suresh K, LEE, Frank W, GANG LUO, YANG, Tian J, HAINES, Paula J, LIFEI WANG, DEMOND, Tonya, DIAMOND, Sharon, CHRIST, David D, GAN, Liang-Shang
Published in Drug metabolism and disposition (01.11.2002)
Published in Drug metabolism and disposition (01.11.2002)
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Journal Article
Effect of Phenobarbital on Hepatic CYP1A1 and CYP1A2 in the Ahr-Null Mouse
Zaher, Hani, Yang, Tian J, Gelboin, Harry V, Fernandez-Salguero, Pedro, Gonzalez, Frank J
Published in Biochemical pharmacology (15.01.1998)
Published in Biochemical pharmacology (15.01.1998)
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Journal Article
Eight Inhibitory Monoclonal Antibodies Define the Role of Individual P-450s in Human Liver Microsomal Diazepam, 7-Ethoxycoumarin, and Imipramine Metabolism
YANG, T. J, KRAUSZ, K. W, YANG SAI, GONZALEZ, F. J, GELBOIN, H. V
Published in Drug metabolism and disposition (01.01.1999)
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Published in Drug metabolism and disposition (01.01.1999)
Journal Article
Inhibitory Monoclonal Antibody to Human Cytochrome P450 2B6
Yang, Tian J, Krausz, Kristopher W, Shou, Magang, Yang, Shen K, Buters, Jeroen T.M, Gonzalez, Frank J, Gelboin, Harry V
Published in Biochemical pharmacology (15.05.1998)
Published in Biochemical pharmacology (15.05.1998)
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Journal Article
Targeted Disruption of the Microsomal Epoxide Hydrolase Gene
Miyata, Masaaki, Kudo, Gen, Lee, Ying-Hue, Fernandez-Salguero, Pedro, Kimura, Shioko, Gonzalez, Frank J., Yang, Tian J., Gelboin, Harry V.
Published in The Journal of biological chemistry (20.08.1999)
Published in The Journal of biological chemistry (20.08.1999)
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Journal Article
Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene
Miyata, M, Kudo, G, Lee, Y H, Yang, T J, Gelboin, H V, Fernandez-Salguero, P, Kimura, S, Gonzalez, F J
Published in The Journal of biological chemistry (20.08.1999)
Published in The Journal of biological chemistry (20.08.1999)
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