RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes
Xin, Yurong, Kim, Jinrang, Okamoto, Haruka, Ni, Min, Wei, Yi, Adler, Christina, Murphy, Andrew J., Yancopoulos, George D., Lin, Calvin, Gromada, Jesper
Published in Cell metabolism (11.10.2016)
Published in Cell metabolism (11.10.2016)
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REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters
Baum, Alina, Ajithdoss, Dharani, Copin, Richard, Zhou, Anbo, Lanza, Kathryn, Negron, Nicole, Ni, Min, Wei, Yi, Mohammadi, Kusha, Musser, Bret, Atwal, Gurinder S, Oyejide, Adelekan, Goez-Gazi, Yenny, Dutton, John, Clemmons, Elizabeth, Staples, Hilary M, Bartley, Carmen, Klaffke, Benjamin, Alfson, Kendra, Gazi, Michal, Gonzalez, Olga, Dick, Jr, Edward, Carrion, Jr, Ricardo, Pessaint, Laurent, Porto, Maciel, Cook, Anthony, Brown, Renita, Ali, Vaneesha, Greenhouse, Jack, Taylor, Tammy, Andersen, Hanne, Lewis, Mark G, Stahl, Neil, Murphy, Andrew J, Yancopoulos, George D, Kyratsous, Christos A
Published in Science (27.11.2020)
Published in Science (27.11.2020)
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Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma
Rabe, Klaus F, Nair, Parameswaran, Brusselle, Guy, Maspero, Jorge F, Castro, Mario, Sher, Lawrence, Zhu, Hongjie, Hamilton, Jennifer D, Swanson, Brian N, Khan, Asif, Chao, Jingdong, Staudinger, Heribert, Pirozzi, Gianluca, Antoni, Christian, Amin, Nikhil, Ruddy, Marcella, Akinlade, Bolanle, Graham, Neil M.H, Stahl, Neil, Yancopoulos, George D, Teper, Ariel
Published in The New England journal of medicine (28.06.2018)
Published in The New England journal of medicine (28.06.2018)
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Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial
Wenzel, Sally, Prof, Castro, Mario, MD, Corren, Jonathan, MD, Maspero, Jorge, MD, Wang, Lin, PhD, Zhang, Bingzhi, PhD, Pirozzi, Gianluca, MD, Sutherland, E Rand, MD, Evans, Robert R, PharmD, Joish, Vijay N, PhD, Eckert, Laurent, PhD, Graham, Neil M H, MD, Stahl, Neil, PhD, Yancopoulos, George D, MD, Louis-Tisserand, Mariana, MD, Teper, Ariel, MD
Published in The Lancet (British edition) (02.07.2016)
Published in The Lancet (British edition) (02.07.2016)
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Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer: a randomized, controlled, double-blind phase 3 trial
Gogishvili, Miranda, Melkadze, Tamar, Makharadze, Tamta, Giorgadze, Davit, Dvorkin, Mikhail, Penkov, Konstantin, Laktionov, Konstantin, Nemsadze, Gia, Nechaeva, Marina, Rozhkova, Irina, Kalinka, Ewa, Gessner, Christian, Moreno-Jaime, Brizio, Passalacqua, Rodolfo, Li, Siyu, McGuire, Kristina, Kaul, Manika, Paccaly, Anne, Quek, Ruben G. W., Gao, Bo, Seebach, Frank, Weinreich, David M., Yancopoulos, George D., Lowy, Israel, Gullo, Giuseppe, Rietschel, Petra
Published in Nature medicine (01.11.2022)
Published in Nature medicine (01.11.2022)
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ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia
Gaudet, Daniel, Gipe, Daniel A, Pordy, Robert, Ahmad, Zahid, Cuchel, Marina, Shah, Prediman K, Chyu, Kuang-Yuh, Sasiela, William J, Chan, Kuo-Chen, Brisson, Diane, Khoury, Etienne, Banerjee, Poulabi, Gusarova, Viktoria, Gromada, Jesper, Stahl, Neil, Yancopoulos, George D, Hovingh, G. Kees
Published in The New England journal of medicine (20.07.2017)
Published in The New England journal of medicine (20.07.2017)
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Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab
Papadopoulos, Nicholas, Martin, Joel, Ruan, Qin, Rafique, Ashique, Rosconi, Michael P., Shi, Ergang, Pyles, Erica A., Yancopoulos, George D., Stahl, Neil, Wiegand, Stanley J.
Published in Angiogenesis (London) (01.06.2012)
Published in Angiogenesis (London) (01.06.2012)
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Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol
Stein, Evan A, Mellis, Scott, Yancopoulos, George D, Stahl, Neil, Logan, Douglas, Smith, William B, Lisbon, Eleanor, Gutierrez, Maria, Webb, Cheryle, Wu, Richard, Du, Yunling, Kranz, Therese, Gasparino, Evelyn, Swergold, Gary D
Published in The New England journal of medicine (22.03.2012)
Published in The New England journal of medicine (22.03.2012)
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Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes
Macdonald, Lynn E., Karow, Margaret, Stevens, Sean, Auerbach, Wojtek, Poueymirou, William T., Yasenchak, Jason, Frendewey, David, Valenzuela, David M., Giallourakis, Cosmas C., Alt, Frederick W., Yancopoulos, George D., Murphy, Andrew J.
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
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IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
Huber, Samuel, Gagliani, Nicola, Zenewicz, Lauren A., Huber, Francis J., Bosurgi, Lidia, Hu, Bo, Hedl, Matija, Zhang, Wei, O’Connor, William, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Booth, Carmen J., Cho, Judy H., Ouyang, Wenjun, Abraham, Clara, Flavell, Richard A.
Published in Nature (London) (08.11.2012)
Published in Nature (London) (08.11.2012)
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ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion
Gusarova, Viktoria, Alexa, Corey A., Na, Erqian, Stevis, Panayiotis E., Xin, Yurong, Bonner-Weir, Susan, Cohen, Jonathan C., Hobbs, Helen H., Murphy, Andrew J., Yancopoulos, George D., Gromada, Jesper
Published in Cell (23.10.2014)
Published in Cell (23.10.2014)
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Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations
Deng, Kai, Pertea, Mihaela, Rongvaux, Anthony, Wang, Leyao, Durand, Christine M., Ghiaur, Gabriel, Lai, Jun, McHugh, Holly L., Hao, Haiping, Zhang, Hao, Margolick, Joseph B., Gurer, Cagan, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Deeks, Steven G., Strowig, Till, Kumar, Priti, Siliciano, Janet D., Salzberg, Steven L., Flavell, Richard A., Shan, Liang, Siliciano, Robert F.
Published in Nature (London) (15.01.2015)
Published in Nature (London) (15.01.2015)
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Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice
Murphy, Andrew J., Macdonald, Lynn E., Stevens, Sean, Karow, Margaret, Dore, Anthony T., Pobursky, Kevin, Huang, Tammy T., Poueymirou, William T., Esau, Lakeisha, Meola, Melissa, Mikulka, Warren, Krueger, Pamela, Fairhurst, Jeanette, Valenzuela, David M., Papadopoulos, Nicholas, Yancopoulos, George D.
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
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Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial
Thaçi, Diamant, Prof, Simpson, Eric L, MD, Beck, Lisa A, Prof, Bieber, Thomas, Prof, Blauvelt, Andrew, MD, Papp, Kim, MD, Soong, Weily, MD, Worm, Margitta, Univ-Prof, Szepietowski, Jacek C, Prof, Sofen, Howard, MD, Kawashima, Makoto, Prof, Wu, Richard, PhD, Weinstein, Steven P, MD, Graham, Neil M H, MD, Pirozzi, Gianluca, MD, Teper, Ariel, MD, Sutherland, E Rand, MD, Mastey, Vera, MS, Stahl, Neil, PhD, Yancopoulos, George D, MD, Ardeleanu, Marius, MD
Published in The Lancet (British edition) (02.01.2016)
Published in The Lancet (British edition) (02.01.2016)
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Use of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells
Xin, Yurong, Kim, Jinrang, Ni, Min, Wei, Yi, Okamoto, Haruka, Lee, Joseph, Adler, Christina, Cavino, Katie, Murphy, Andrew J., Yancopoulos, George D., Lin, Hsin Chieh, Gromada, Jesper
Published in Proceedings of the National Academy of Sciences - PNAS (22.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (22.03.2016)
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Journal Article
Intravitreal Aflibercept for Diabetic Macular Edema
Korobelnik, Jean-François, MD, Do, Diana V., MD, Schmidt-Erfurth, Ursula, MD, Boyer, David S., MD, Holz, Frank G., MD, Heier, Jeffrey S., MD, Midena, Edoardo, MD, Kaiser, Peter K., MD, Terasaki, Hiroko, MD, Marcus, Dennis M., MD, Nguyen, Quan D., MD, Jaffe, Glenn J., MD, Slakter, Jason S., MD, Simader, Christian, MD, Soo, Yuhwen, PhD, Schmelter, Thomas, PhD, Yancopoulos, George D., MD, PhD, Stahl, Neil, PhD, Vitti, Robert, MD, Berliner, Alyson J., MD, PhD, Zeitz, Oliver, MD, Metzig, Carola, MD, Brown, David M., MD
Published in Ophthalmology (Rochester, Minn.) (01.11.2014)
Published in Ophthalmology (Rochester, Minn.) (01.11.2014)
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Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis
Hamilton, Jennifer D., PhD, Suárez-Fariñas, Mayte, PhD, Dhingra, Nikhil, BS, Cardinale, Irma, MSc, Li, Xuan, PhD, Kostic, Ana, PhD, Ming, Jeffrey E., MD, PhD, Radin, Allen R., MD, Krueger, James G., MD, Graham, Neil, MD, Yancopoulos, George D., MD, PhD, Pirozzi, Gianluca, MD, PhD, Guttman-Yassky, Emma, MD, PhD
Published in Journal of allergy and clinical immunology (01.12.2014)
Published in Journal of allergy and clinical immunology (01.12.2014)
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Humanized mouse model supports development, function, and tissue residency of human natural killer cells
Herndler-Brandstetter, Dietmar, Shan, Liang, Yao, Yi, Stecher, Carmen, Plajer, Valerie, Lietzenmayer, Melanie, Strowig, Till, de Zoete, Marcel R., Palm, Noah W., Chen, Jie, Blish, Catherine A., Frleta, Davor, Gurer, Cagan, Macdonald, Lynn E., Murphy, Andrew J., Yancopoulos, George D., Montgomery, Ruth R., Flavell, Richard A.
Published in Proceedings of the National Academy of Sciences - PNAS (07.11.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (07.11.2017)
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Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration
Heier, Jeffrey S., MD, Brown, David M., MD, Chong, Victor, MD, Korobelnik, Jean-Francois, MD, Kaiser, Peter K., MD, Nguyen, Quan Dong, MD, Kirchhof, Bernd, MD, Ho, Allen, MD, Ogura, Yuichiro, MD, Yancopoulos, George D., MD, PhD, Stahl, Neil, MD, Vitti, Robert, MD, Berliner, Alyson J., MD, PhD, Soo, Yuhwen, PhD, Anderesi, Majid, MD, Groetzbach, Georg, MD, Sommerauer, Bernd, PhD, Sandbrink, Rupert, MD, PhD, Simader, Christian, MD, Schmidt-Erfurth, Ursula, MD
Published in Ophthalmology (Rochester, Minn.) (01.12.2012)
Published in Ophthalmology (Rochester, Minn.) (01.12.2012)
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Infections in Dupilumab Clinical Trials in Atopic Dermatitis: A Comprehensive Pooled Analysis
Eichenfield, Lawrence F., Bieber, Thomas, Beck, Lisa A., Simpson, Eric L., Thaçi, Diamant, de Bruin-Weller, Marjolein, Deleuran, Mette, Silverberg, Jonathan I., Ferrandiz, Carlos, Fölster-Holst, Regina, Chen, Zhen, Graham, Neil M. H., Pirozzi, Gianluca, Akinlade, Bolanle, Yancopoulos, George D., Ardeleanu, Marius
Published in American journal of clinical dermatology (01.06.2019)
Published in American journal of clinical dermatology (01.06.2019)
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