Effect of temperature ramp rate during the primary drying process on the properties of amorphous-based lyophilized cake, Part 2: Successful lyophilization by adopting a fast ramp rate during primary drying in protein formulations
Ohori, Ryo, Akita, Tomomi, Yamashita, Chikamasa
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2018)
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2018)
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Journal Article
Efficient optimization of high-dose formulation of novel lyophilizates for dry powder inhalation by the combination of response surface methodology and time-of-flight measurement
Ohori, Ryo, Kiuchi, Sakurako, Sugiyama, Shintaro, Miyamoto, Kahori, Akita, Tomomi, Yamashita, Chikamasa
Published in International journal of pharmaceutics (15.05.2020)
Published in International journal of pharmaceutics (15.05.2020)
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Journal Article
Effects of temperature ramp rate during the primary drying process on the properties of amorphous-based lyophilized cake, Part 1: Cake characterization, collapse temperature and drying behavior
Ohori, Ryo, Yamashita, Chikamasa
Published in Journal of drug delivery science and technology (01.06.2017)
Published in Journal of drug delivery science and technology (01.06.2017)
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Journal Article
Pulmonary administration of 1,25-dihydroxyvitamin D3 to the lungs induces alveolar regeneration in a mouse model of chronic obstructive pulmonary disease
Horiguchi, Michiko, Hirokawa, Mai, Abe, Kaori, Kumagai, Harumi, Yamashita, Chikamasa
Published in Journal of controlled release (10.07.2016)
Published in Journal of controlled release (10.07.2016)
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Journal Article
Pulmonary administration of phosphoinositide 3-kinase inhibitor is a curative treatment for chronic obstructive pulmonary disease by alveolar regeneration
Horiguchi, Michiko, Oiso, Yuki, Sakai, Hitomi, Motomura, Tomoki, Yamashita, Chikamasa
Published in Journal of controlled release (10.09.2015)
Published in Journal of controlled release (10.09.2015)
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Journal Article
Systemic Delivery of hGhrelin Derivative by Lyophilizate for Dry Powder Inhalation System in Monkeys
Miyamoto, Kahori, Ishibashi, Yuko, Akita, Tomomi, Yamashita, Chikamasa
Published in Pharmaceutics (07.02.2021)
Published in Pharmaceutics (07.02.2021)
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A novel diagnostic system to evaluate epidermal growth factor receptor impact as a prognostic and therapeutic indicator for lung adenocarcinoma
Takakuwa, Kazuya, Mogushi, Kaoru, Han, Min, Fujii, Tomoaki, Hosoya, Masaki, Yamanami, Arina, Akita, Tomomi, Yamashita, Chikamasa, Hayashida, Tetsu, Kato, Shunsuke, Yamaguchi, Shigeo
Published in Scientific reports (10.04.2020)
Published in Scientific reports (10.04.2020)
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Characterization of a spontaneous mouse model of mild, accelerated aging via ECM degradation in emphysematous lungs
Tanino, Ryosuke, Tsubata, Yukari, Hotta, Takamasa, Okimoto, Tamio, Amano, Yoshihiro, Takechi, Mayumi, Tanaka, Tetsuya, Akita, Tomomi, Nagase, Mamiko, Yamashita, Chikamasa, Wada, Koichiro, Isobe, Takeshi
Published in Scientific reports (03.07.2023)
Published in Scientific reports (03.07.2023)
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Journal Article
Intracellular Drug Delivery Process of Am80-Encapsulated Lipid Nanoparticles Aiming for Alveolar Regeneration
Akita, Tomomi, Oda, Kazuaki, Narukawa, Satoru, Morita, Yuki, Tange, Kota, Nakai, Yuta, Yamashita, Chikamasa
Published in Pharmaceuticals (Basel, Switzerland) (01.06.2023)
Published in Pharmaceuticals (Basel, Switzerland) (01.06.2023)
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Intracerebroventricular administration of oxytocin and intranasal administration of the oxytocin derivative improve β‐amyloid peptide (25–35)‐induced memory impairment in mice
Takahashi, Junpei, Ueta, Yudai, Yamada, Daisuke, Sasaki‐Hamada, Sachie, Iwai, Takashi, Akita, Tomomi, Yamashita, Chikamasa, Saitoh, Akiyoshi, Oka, Jun‐Ichiro
Published in Neuropsychopharmacology reports (01.12.2022)
Published in Neuropsychopharmacology reports (01.12.2022)
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Method for Pulmonary Administration Using Negative Pressure Generated by Inspiration in Mice
Oiso, Yuki, Akita, Tomomi, Kato, Daiki, Yamashita, Chikamasa
Published in Pharmaceutics (25.02.2020)
Published in Pharmaceutics (25.02.2020)
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Pulmonary administration of integrin-nanoparticles regenerates collapsed alveoli
Horiguchi, Michiko, Kojima, Hisako, Sakai, Hitomi, Kubo, Hiroshi, Yamashita, Chikamasa
Published in Journal of controlled release (10.08.2014)
Published in Journal of controlled release (10.08.2014)
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Am80-Encapsulated Lipid Nanoparticles, Developed with the Aim of Achieving Alveolar Regeneration, Have an Improvement Effect on Pulmonary Emphysema
Akita, Tomomi, Morita, Yuki, Kawai, Takehiro, Oda, Kazuaki, Tange, Kota, Nakai, Yuta, Yamashita, Chikamasa
Published in Pharmaceutics (22.12.2022)
Published in Pharmaceutics (22.12.2022)
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Journal Article
Pulmonary administration of curcumin inhibits B16F10 melanoma lung metastasis and invasion in mice
Shimada, Ken, Ushijima, Kentaro, Suzuki, Chisato, Horiguchi, Michiko, Ando, Hitoshi, Akita, Tomomi, Shimamura, Mizuki, Fujii, Junki, Yamashita, Chikamasa, Fujimura, Akio
Published in Cancer chemotherapy and pharmacology (01.08.2018)
Published in Cancer chemotherapy and pharmacology (01.08.2018)
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Pulmonary Administration of GW0742, a High-Affinity Peroxisome Proliferator-Activated Receptor Agonist, Repairs Collapsed Alveoli in an Elastase-Induced Mouse Model of Emphysema
Ozawa, Chihiro, Horiguchi, Michiko, Akita, Tomomi, Oiso, Yuki, Abe, Kaori, Motomura, Tomoki, Yamashita, Chikamasa
Published in Biological & pharmaceutical bulletin (01.05.2016)
Published in Biological & pharmaceutical bulletin (01.05.2016)
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