Enhancement of metabolic flux toward ε-poly-l-lysine biosynthesis by targeted inactivation of concomitant polyene macrolide biosynthesis in Streptomyces albulus
Yamanaka, Kazuya, Hamano, Yoshimitsu, Oikawa, Tadao
Published in Journal of bioscience and bioengineering (01.05.2020)
Published in Journal of bioscience and bioengineering (01.05.2020)
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Journal Article
Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A
Yamanaka, Kazuya, Reynolds, Kirk A., Kersten, Roland D., Ryan, Katherine S., Gonzalez, David J., Nizet, Victor, Dorrestein, Pieter C., Moore, Bradley S.
Published in Proceedings of the National Academy of Sciences - PNAS (04.02.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (04.02.2014)
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Journal Article
The Stereocontrolled Biosynthesis of Mirror-Symmetric 2,4-Diaminobutyric Acid Homopolymers Is Critically Governed by Adenylation Activations
Yamanaka, Kazuya, Fukumoto, Hibiki, Takehara, Munenori, Hamano, Yoshimitsu, Oikawa, Tadao
Published in ACS chemical biology (17.07.2020)
Published in ACS chemical biology (17.07.2020)
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Journal Article
Characterization of an l-α,β-diaminopropionic acid polymer with comb-like structure isolated from a poly(ε-l-lysine)-producing Streptomyces sp
Takehara, Munenori, Saimura, Masayuki, Inaba, Haruka, Kato, Yoshinao, Muro, Shogo, Matsunaga, Tatsuki, Yamanaka, Kazuya
Published in Applied microbiology and biotechnology (01.04.2021)
Published in Applied microbiology and biotechnology (01.04.2021)
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Journal Article
A Peptidyl-Transesterifying Type I Thioesterase in Salinamide Biosynthesis
Ray, Lauren, Yamanaka, Kazuya, Moore, Bradley S.
Published in Angewandte Chemie (International ed.) (04.01.2016)
Published in Angewandte Chemie (International ed.) (04.01.2016)
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Journal Article
Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster
Reynolds, Kirk A., Luhavaya, Hanna, Li, Jie, Dahesh, Samira, Nizet, Victor, Yamanaka, Kazuya, Moore, Bradley S.
Published in Journal of antibiotics (01.02.2018)
Published in Journal of antibiotics (01.02.2018)
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Journal Article
Mechanism of ε-Poly-L-Lysine Production and Accumulation Revealed by Identification and Analysis of an ε-Poly-L-Lysine-Degrading Enzyme
Yamanaka, Kazuya, Kito, Naoko, Imokawa, Yuuki, Maruyama, Chitose, Utagawa, Takashi, Hamano, Yoshimitsu
Published in Applied and Environmental Microbiology (01.09.2010)
Published in Applied and Environmental Microbiology (01.09.2010)
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Journal Article
Directed natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilis
Li, Yongxin, Li, Zhongrui, Yamanaka, Kazuya, Xu, Ying, Zhang, Weipeng, Vlamakis, Hera, Kolter, Roberto, Moore, Bradley S, Qian, Pei-Yuan
Published in Scientific reports (24.03.2015)
Published in Scientific reports (24.03.2015)
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Journal Article
Structures and Comparative Characterization of Biosynthetic Gene Clusters for Cyanosporasides, Enediyne-Derived Natural Products from Marine Actinomycetes
Lane, Amy L, Nam, Sang-Jip, Fukuda, Takashi, Yamanaka, Kazuya, Kauffman, Christopher A, Jensen, Paul R, Fenical, William, Moore, Bradley S
Published in Journal of the American Chemical Society (20.03.2013)
Published in Journal of the American Chemical Society (20.03.2013)
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Journal Article
First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria
Takeuchi, Yamato, Ushimaru, Kazunori, Kaneda, Kohei, Maruyama, Chitose, Ito, Takashi, Yamanaka, Kazuya, Ogasawara, Yasushi, Katano, Hajime, Kato, Yasuo, Dairi, Tohru, Hamano, Yoshimitsu
Published in Communications biology (26.10.2022)
Published in Communications biology (26.10.2022)
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Journal Article
Mutational analysis of the three tandem domains of ε-poly-l-lysine synthetase catalyzing the l-lysine polymerization reaction
Kito, Naoko, Maruyama, Chitose, Yamanaka, Kazuya, Imokawa, Yuuki, Utagawa, Takashi, Hamano, Yoshimitsu
Published in Journal of bioscience and bioengineering (01.05.2013)
Published in Journal of bioscience and bioengineering (01.05.2013)
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Journal Article
Development of a recombinant ε-poly-L-lysine synthetase expression system to perform mutational analysis
Yamanaka, Kazuya, Kito, Naoko, Kita, Akihiro, Imokawa, Yuuki, Maruyama, Chitose, Utagawa, Takashi, Hamano, Yoshimitsu
Published in Journal of bioscience and bioengineering (01.06.2011)
Published in Journal of bioscience and bioengineering (01.06.2011)
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Journal Article
Crystal structure of the adenylation domain from an ε-poly-l-lysine synthetase provides molecular mechanism for substrate specificity
Okamoto, Takaki, Yamanaka, Kazuya, Hamano, Yoshimitsu, Nagano, Shingo, Hino, Tomoya
Published in Biochemical and biophysical research communications (12.03.2022)
Published in Biochemical and biophysical research communications (12.03.2022)
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Journal Article
Functional evaluation of an electrophilic focused library to identify a covalent inhibitor against intrinsically disordered circadian clock transcription factors
Yamanaka, Kazuya, Inoue, Yoshihisa, Imanishi, Miki, Ohkanda, Junko
Published in Bioorganic & medicinal chemistry letters (15.01.2024)
Published in Bioorganic & medicinal chemistry letters (15.01.2024)
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