An activation of LC3A-mediated autophagy contributes to de novo and acquired resistance to EGFR tyrosine kinase inhibitors in lung adenocarcinoma
Nihira, Kaito, Miki, Yasuhiro, Iida, Shinya, Narumi, Sodai, Ono, Katsuhiko, Iwabuchi, Erina, Ise, Kazue, Mori, Kazushige, Saito, Mikiyoshi, Ebina, Masahito, Sato, Ikuro, Maemondo, Makoto, Yamada-Okabe, Hisafumi, Kondo, Takashi, Sasano, Hironobu
Published in The Journal of pathology (01.10.2014)
Published in The Journal of pathology (01.10.2014)
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Gene expression analysis of renal carcinoma: adipose differentiation-related protein as a potential diagnostic and prognostic biomarker for clear-cell renal carcinoma
Yao, Masahiro, Tabuchi, Hisahiro, Nagashima, Yoji, Baba, Masaya, Nakaigawa, Noboru, Ishiguro, Hitoshi, Hamada, Kenji, Inayama, Yoshiaki, Kishida, Takeshi, Hattori, Keiko, Yamada-Okabe, Hisafumi, Kubota, Yoshinobu
Published in The Journal of pathology (01.02.2005)
Published in The Journal of pathology (01.02.2005)
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A new disulfide‐linked dimer of a single‐chain antibody fragment against human CD47 induces apoptosis in lymphoid malignant cells via the hypoxia inducible factor‐1α pathway
Sagawa, Morihiko, Shimizu, Takatsune, Fukushima, Naoshi, Kinoshita, Yasuko, Ohizumi, Iwao, Uno, Shinsuke, Kikuchi, Yasufumi, Ikeda, Yasuo, Yamada‐Okabe, Hisafumi, Kizaki, Masahiro
Published in Cancer science (01.06.2011)
Published in Cancer science (01.06.2011)
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A defucosylated anti‐CD317 antibody exhibited enhanced antibody‐dependent cellular cytotoxicity against primary myeloma cells in the presence of effectors from patients
Ishiguro, Takahiro, Kawai, Shigeto, Habu, Kiyoshi, Sugimoto, Masamichi, Shiraiwa, Hirotake, Iijima, Shigeyuki, Ozaki, Shuji, Matsumoto, Toshio, Yamada‐Okabe, Hisafumi
Published in Cancer science (01.10.2010)
Published in Cancer science (01.10.2010)
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Interferon‐α enhances CD317 expression and the antitumor activity of anti‐CD317 monoclonal antibody in renal cell carcinoma xenograft models
Kawai, Shigeto, Azuma, Yumiko, Fujii, Etsuko, Furugaki, Kou, Ozaki, Shuji, Matsumoto, Toshio, Kosaka, Masaaki, Yamada‐Okabe, Hisafumi
Published in Cancer science (01.12.2008)
Published in Cancer science (01.12.2008)
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The Significance of MMP-1 in EGFR-TKI-Resistant Lung Adenocarcinoma: Potential for Therapeutic Targeting
Saito, Ryoko, Miki, Yasuhiro, Ishida, Naoya, Inoue, Chihiro, Kobayashi, Masayuki, Hata, Shuko, Yamada-Okabe, Hisafumi, Okada, Yoshinori, Sasano, Hironobu
Published in International journal of molecular sciences (18.02.2018)
Published in International journal of molecular sciences (18.02.2018)
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Anti-glypican 3 antibody as a potential antitumor agent for human liver cancer
Ishiguro, Takahiro, Sugimoto, Masamichi, Kinoshita, Yasuko, Miyazaki, Yoko, Nakano, Kiyotaka, Tsunoda, Hiroyuki, Sugo, Izumi, Ohizumi, Iwao, Aburatani, Hiroyuki, Hamakubo, Takao, Kodama, Tatsuhiko, Tsuchiya, Masayuki, Yamada-Okabe, Hisafumi
Published in Cancer research (Chicago, Ill.) (01.12.2008)
Published in Cancer research (Chicago, Ill.) (01.12.2008)
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Similar changes of hypothalamic feeding‐regulating peptides mRNAs and plasma leptin levels in PTHrP‐, LIF‐secreting tumors‐induced cachectic rats and adjuvant arthritic rats
Suzuki, Hitoshi, Hashimoto, Hirofumi, Kawasaki, Makoto, Watanabe, Miho, Otsubo, Hiroki, Ishikura, Toru, Fujihara, Hiroaki, Ohnishi, Hideo, Onuma, Etsuro, Yamada‐Okabe, Hisafumi, Takuwa, Yoh, Ogata, Etsuro, Nakamura, Toshitaka, Ueta, Yoichi
Published in International journal of cancer (01.05.2011)
Published in International journal of cancer (01.05.2011)
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Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection
Iizuka, Norio, Oka, Masaaki, Yamada-Okabe, Hisafumi, Nishida, Minekatsu, Maeda, Yoshitaka, Mori, Naohide, Takao, Takashi, Tamesa, Takao, Tangoku, Akira, Tabuchi, Hisahiro, Hamada, Kenji, Nakayama, Hironobu, Ishitsuka, Hideo, Miyamoto, Takanobu, Hirabayashi, Akira, Uchimura, Shunji, Hamamoto, Yoshihiko
Published in The Lancet (British edition) (15.03.2003)
Published in The Lancet (British edition) (15.03.2003)
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Tumor HLA‐DR expression linked to early intrahepatic recurrence of hepatocellular carcinoma
Matoba, Katsuhiro, Iizuka, Norio, Gondo, Toshikazu, Ishihara, Tokuhiro, Yamada‐Okabe, Hisafumi, Tamesa, Takao, Takemoto, Norikazu, Hashimoto, Kiichiro, Sakamoto, Kazuhiko, Miyamoto, Takanobu, Uchimura, Shunji, Hamamoto, Yoshihiko, Oka, Masaaki
Published in International journal of cancer (10.06.2005)
Published in International journal of cancer (10.06.2005)
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Intratumoral Localization of Aromatase and Interaction between Stromal and Parenchymal Cells in the Non-Small Cell Lung Carcinoma Microenvironment
MIKI, Yasuhiro, SUZUKI, Takashi, KONDO, Takashi, YAMADA-OKABE, Hisafumi, SASANO, Hironobu, ABE, Keiko, SUZUKI, Satoshi, NIIKAWA, Hiromichi, LIDA, Shinya, HATA, Shuko, AKAHIRA, Jun-Ichi, MORI, Kazushige, EVANS, Dean B
Published in Cancer research (Chicago, Ill.) (15.08.2010)
Published in Cancer research (Chicago, Ill.) (15.08.2010)
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LGR5-Positive Colon Cancer Stem Cells Interconvert with Drug-Resistant LGR5-Negative cells and are Capable of Tumor Reconstitution
Kobayashi, Shinta, Yamada-Okabe, Hisafumi, Suzuki, Masami, Natori, Osamu, Kato, Atsuhiko, Matsubara, Koichi, Jau Chen, Yu, Yamazaki, Masaki, Funahashi, Shinichi, Yoshida, Kenji, Hashimoto, Eri, Watanabe, Yoshinori, Mutoh, Hironori, Ashihara, Motooki, Kato, Chie, Watanabe, Takeshi, Yoshikubo, Takashi, Tamaoki, Norikazu, Ochiya, Takahiro, Kuroda, Masahiko, Levine, Arnold J., Yamazaki, Tatsumi
Published in Stem cells (Dayton, Ohio) (01.12.2012)
Published in Stem cells (Dayton, Ohio) (01.12.2012)
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Combination with a defucosylated anti-HM1.24 monoclonal antibody plus lenalidomide induces marked ADCC against myeloma cells and their progenitors
Harada, Takeshi, Ozaki, Shuji, Oda, Asuka, Tsuji, Daisuke, Ikegame, Akishige, Iwasa, Masami, Udaka, Kengo, Fujii, Shiro, Nakamura, Shingen, Miki, Hirokazu, Kagawa, Kumiko, Kuroda, Yoshiaki, Kawai, Shigeto, Itoh, Kohji, Yamada-Okabe, Hisafumi, Matsumoto, Toshio, Abe, Masahiro
Published in PloS one (26.12.2013)
Published in PloS one (26.12.2013)
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Generation of a humanized anti-glypican 3 antibody by CDR grafting and stability optimization
Nakano, Kiyotaka, Ishiguro, Takahiro, Konishi, Hiroko, Tanaka, Megumi, Sugimoto, Masamichi, Sugo, Izumi, Igawa, Tomoyuki, Tsunoda, Hiroyuki, Kinoshita, Yasuko, Habu, Kiyoshi, Orita, Tetsuro, Tsuchiya, Masayuki, Hattori, Kunihiro, Yamada-Okabe, Hisafumi
Published in Anti-cancer drugs (01.11.2010)
Published in Anti-cancer drugs (01.11.2010)
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Downregulation of uPARAP mediates cytoskeletal rearrangements and decreases invasion and migration properties in glioma cells
Takahashi, Satoshi, Yamada-Okabe, Hisafumi, Hamada, Kenji, Ohta, Shigeki, Kawase, Takeshi, Yoshida, Kazunari, Toda, Masahiro
Published in Journal of neuro-oncology (01.06.2011)
Published in Journal of neuro-oncology (01.06.2011)
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Parathyroid hormone–related protein (PTHrP) as a causative factor of cancer‐associated wasting: Possible involvement of PTHrP in the repression of locomotor activity in rats bearing human tumor xenografts
Onuma, Etsuro, Tsunenari, Toshiaki, Saito, Hidemi, Sato, Koh, Yamada‐Okabe, Hisafumi, Ogata, Etsuro
Published in International journal of cancer (01.09.2005)
Published in International journal of cancer (01.09.2005)
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Involvement of cyclooxygenase‐2 in the tumor site‐dependent production of parathyroid hormone‐related protein in colon 26 carcinoma
Saito, Hidemi, Inagaki, Yukiko, Tsunenari, Toshiaki, Ura, Masako, Mizuno, Hideaki, Fujimoto‐Ouchi, Kaori, Onuma, Etsuro, Sato, Koh, Ogata, Etsuro, Yamada‐Okabe, Hisafumi
Published in Cancer science (01.10.2007)
Published in Cancer science (01.10.2007)
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Modulation at a cellular level of the thyroid hormone receptor-mediated gene expression by 1,2,5,6,9,10-hexabromocyclododecane (HBCD), 4,4′-diiodobiphenyl (DIB), and nitrofen (NIP)
Yamada-Okabe, Toshiko, Sakai, Haruya, Kashima, Yuji, Yamada-Okabe, Hisafumi
Published in Toxicology letters (15.01.2005)
Published in Toxicology letters (15.01.2005)
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Crystal Structure of Uridine-diphospho-N-acetylglucosamine Pyrophosphorylase from Candida albicans and Catalytic Reaction Mechanism
Maruyama, Daisuke, Nishitani, Yuichi, Nonaka, Tsuyoshi, Kita, Akiko, Fukami, Takaaki A., Mio, Toshiyuki, Yamada-Okabe, Hisafumi, Yamada-Okabe, Toshiko, Miki, Kunio
Published in The Journal of biological chemistry (08.06.2007)
Published in The Journal of biological chemistry (08.06.2007)
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