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Published in Nature communications (03.12.2013)
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Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity
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Published in The Journal of biological chemistry (01.07.2023)
Published in The Journal of biological chemistry (01.07.2023)
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Exploratory analysis using machine learning of predictive factors for falls in type 2 diabetes
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Published in Scientific reports (13.07.2022)
Published in Scientific reports (13.07.2022)
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Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis
Yamada, Naoya, Karasawa, Tadayoshi, Ito, Junya, Yamamuro, Daisuke, Morimoto, Kazushi, Nakamura, Toshitaka, Komada, Takanori, Baatarjav, Chintogtokh, Saimoto, Yuma, Jinnouchi, Yuka, Watanabe, Kazuhisa, Miura, Kouichi, Yahagi, Naoya, Nakagawa, Kiyotaka, Matsumura, Takayoshi, Yamada, Ken-ichi, Ishibashi, Shun, Sata, Naohiro, Conrad, Marcus, Takahashi, Masafumi
Published in Nature communications (12.03.2024)
Published in Nature communications (12.03.2024)
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GR‐KLF15 pathway controls hepatic lipogenesis during fasting
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Published in The FEBS journal (01.01.2024)
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Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance
Iwasaki, Hitoshi, Ishikawa, Mayumi, Hasty, Alyssa H, Matsui, Toshiyuki, Ishigaki, Naomi, Takahashi, Akimitsu, Inoue, Noriyuki, Okada, Sumiyo, Toyoshima, Hideo, Ohashi, Ken, Osuga, Jun-ichi, Sone, Hirohito, Yatoh, Sigeru, Nakagawa, Yoshimi, Matsuzaka, Takashi, Iwasaki, Yuko, Yamamoto, Takashi, Suzuki, Hiroaki, Kumadaki, Shin, Yahagi, Naoya, Kato, Toyonori, Karasawa, Tadayoshi, Atsumi, Ayaka, Sekiya, Motohiro, Yamada, Nobuhiro, Shimano, Hitoshi
Published in Nature medicine (01.10.2007)
Published in Nature medicine (01.10.2007)
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Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
Sekiya, Motohiro, Ma, Yang, Kainoh, Kenta, Saito, Kenji, Yamazaki, Daichi, Tsuyuzaki, Tomomi, Chen, Wanpei, Adi Putri, Putu Indah Paramita, Ohno, Hiroshi, Miyamoto, Takafumi, Takeuchi, Yoshinori, Murayama, Yuki, Sugano, Yoko, Osaki, Yoshinori, Iwasaki, Hitoshi, Yahagi, Naoya, Suzuki, Hiroaki, Motomura, Kaori, Matsuzaka, Takashi, Murata, Kazuya, Mizuno, Seiya, Takahashi, Satoru, Shimano, Hitoshi
Published in Cell reports (Cambridge) (29.08.2023)
Published in Cell reports (Cambridge) (29.08.2023)
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Effects of Branched-Chain Amino Acids on Skeletal Muscle, Glycemic Control, and Neuropsychological Performance in Elderly Persons with Type 2 Diabetes Mellitus: An Exploratory Randomized Controlled Trial
Matsuda, Takaaki, Suzuki, Hiroaki, Sugano, Yoko, Suzuki, Yasuhiro, Yamanaka, Daisuke, Araki, Risa, Yahagi, Naoya, Sekiya, Motohiro, Kawakami, Yasushi, Osaki, Yoshinori, Iwasaki, Hitoshi, Hashimoto, Koichi, Takahashi, Shin-Ichiro, Hada, Yasushi, Shimano, Hitoshi
Published in Nutrients (01.10.2022)
Published in Nutrients (01.10.2022)
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Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism
Sharma, Rahul, Matsuzaka, Takashi, Kaushik, Mahesh K., Sugasawa, Takehito, Ohno, Hiroshi, Wang, Yunong, Motomura, Kaori, Shimura, Takuya, Okajima, Yuka, Mizunoe, Yuhei, Ma, Yang, Saber, Zahara M., Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Aita, Yuichi, Han, Song-iee, Takeuchi, Yoshinori, Yahagi, Naoya, Miyamoto, Takafumi, Sekiya, Motohiro, Nakagawa, Yoshimi, Shimano, Hitoshi
Published in Scientific reports (26.03.2019)
Published in Scientific reports (26.03.2019)
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High protein diet-induced metabolic changes are transcriptionally regulated via KLF15-dependent and independent pathways
Mehrazad Saber, Zahra, Takeuchi, Yoshinori, Sawada, Yoshikazu, Aita, Yuichi, Ho, Man Hei, Karkoutly, Samia, Tao, Duhan, Katabami, Kyoka, Ye, Chen, Murayama, Yuki, Shikama, Akito, Masuda, Yukari, Izumida, Yoshihiko, Miyamoto, Takafumi, Matsuzaka, Takashi, Sugasawa, Takehito, Takekoshi, Kazuhiro, Kawakami, Yasushi, Shimano, Hitoshi, Yahagi, Naoya
Published in Biochemical and biophysical research communications (10.12.2021)
Published in Biochemical and biophysical research communications (10.12.2021)
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Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice
Suzuki-Kemuriyama, Noriko, Matsuzaka, Takashi, Kuba, Motoko, Ohno, Hiroshi, Han, Song-Iee, Takeuchi, Yoshinori, Isaka, Masaaki, Kobayashi, Kazuto, Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Miyajima, Katsuhiro, Nakae, Dai, Yahagi, Naoya, Nakagawa, Yoshimi, Sone, Hirohito, Yamada, Nobuhiro, Shimano, Hitoshi
Published in PloS one (22.06.2016)
Published in PloS one (22.06.2016)
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New balance capability index as a screening tool for mild cognitive impairment
Suzuki, Yasuhiro, Tsubaki, Takumi, Nakaya, Kensuke, Kondo, Genta, Takeuchi, Yoshinori, Aita, Yuichi, Murayama, Yuki, Shikama, Akito, Masuda, Yukari, Suzuki, Hiroaki, Kawakami, Yasushi, Shimano, Hitoshi, Arai, Tetsuaki, Hada, Yasushi, Yahagi, Naoya
Published in BMC geriatrics (04.02.2023)
Published in BMC geriatrics (04.02.2023)
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KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting
Takeuchi, Yoshinori, Yahagi, Naoya, Aita, Yuichi, Murayama, Yuki, Sawada, Yoshikazu, Piao, Xiaoying, Toya, Naoki, Oya, Yukari, Shikama, Akito, Takarada, Ayako, Masuda, Yukari, Nishi, Makiko, Kubota, Midori, Izumida, Yoshihiko, Yamamoto, Takashi, Sekiya, Motohiro, Matsuzaka, Takashi, Nakagawa, Yoshimi, Urayama, Osamu, Kawakami, Yasushi, Iizuka, Yoko, Gotoda, Takanari, Itaka, Keiji, Kataoka, Kazunori, Nagai, Ryozo, Kadowaki, Takashi, Yamada, Nobuhiro, Lu, Yuan, Jain, Mukesh K., Shimano, Hitoshi
Published in Cell reports (Cambridge) (30.08.2016)
Published in Cell reports (Cambridge) (30.08.2016)
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Deciphering genetic signatures by whole exome sequencing in a case of co-prevalence of severe renal hypouricemia and diabetes with impaired insulin secretion
Sekiya, Motohiro, Matsuda, Takaaki, Yamamoto, Yuki, Furuta, Yasuhisa, Ohyama, Mariko, Murayama, Yuki, Sugano, Yoko, Ohsaki, Yoshinori, Iwasaki, Hitoshi, Yahagi, Naoya, Yatoh, Shigeru, Suzuki, Hiroaki, Shimano, Hitoshi
Published in BMC medical genetics (06.05.2020)
Published in BMC medical genetics (06.05.2020)
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Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice
Okajima, Yuka, Matsuzaka, Takashi, Miyazaki, Shun, Motomura, Kaori, Ohno, Hiroshi, Sharma, Rahul, Shimura, Takuya, Istiqamah, Nurani, Han, Song-iee, Mizunoe, Yuhei, Osaki, Yoshinori, Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Sone, Hirohito, Miyamoto, Takafumi, Aita, Yuichi, Takeuchi, Yoshinori, Sekiya, Motohiro, Yahagi, Naoya, Nakagawa, Yoshimi, Tomita, Tsutomu, Shimano, Hitoshi
Published in Biochimica et biophysica acta. Molecular basis of disease (01.04.2022)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.04.2022)
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Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance
Ohno, Hiroshi, Matsuzaka, Takashi, Tang, Nie, Sharma, Rahul, Motomura, Kaori, Shimura, Takuya, Satoh, Aoi, Han, Song-iee, Takeuchi, Yoshinori, Aita, Yuichi, Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Sekiya, Motohiro, Nakagawa, Yoshimi, Sone, Hirohito, Yahagi, Naoya, Yamada, Nobuhiro, Higami, Yoshikazu, Shimano, Hitoshi
Published in Endocrinology (Philadelphia) (01.06.2018)
Published in Endocrinology (Philadelphia) (01.06.2018)
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