MAPKAP Kinase-2 Drives Expression of Angiogenic Factors by Tumor-Associated Macrophages in a Model of Inflammation-Induced Colon Cancer
Suarez-Lopez, Lucia, Kong, Yi Wen, Sriram, Ganapathy, Patterson, Jesse C, Rosenberg, Samantha, Morandell, Sandra, Haigis, Kevin M, Yaffe, Michael B
Published in Frontiers in immunology (23.02.2021)
Published in Frontiers in immunology (23.02.2021)
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14-3-3 Proteins—a focus on cancer and human disease
Wilker, Erik, Yaffe, Michael B.
Published in Journal of molecular and cellular cardiology (01.09.2004)
Published in Journal of molecular and cellular cardiology (01.09.2004)
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Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain - binding peptide macrocycles
Hymel, David, Tsuji, Kohei, Grant, Robert A, Chingle, Ramesh M, Kunciw, Dominique L, Yaffe, Michael B, Burke, Terrence R
Published in Organic & biomolecular chemistry (22.09.2021)
Published in Organic & biomolecular chemistry (22.09.2021)
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Systematic Discovery of In Vivo Phosphorylation Networks
Linding, Rune, Jensen, Lars Juhl, Ostheimer, Gerard J., van Vugt, Marcel A.T.M., Jørgensen, Claus, Miron, Ioana M., Diella, Francesca, Colwill, Karen, Taylor, Lorne, Elder, Kelly, Metalnikov, Pavel, Nguyen, Vivian, Pasculescu, Adrian, Jin, Jing, Park, Jin Gyoon, Samson, Leona D., Woodgett, James R., Russell, Robert B., Bork, Peer, Yaffe, Michael B., Pawson, Tony
Published in Cell (29.06.2007)
Published in Cell (29.06.2007)
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A Reversible Gene-Targeting Strategy Identifies Synthetic Lethal Interactions between MK2 and p53 in the DNA Damage Response In Vivo
Morandell, Sandra, Reinhardt, H. Christian, Cannell, Ian G., Kim, Jacob S., Ruf, Daniela M., Mitra, Tanya, Couvillon, Anthony D., Jacks, Tyler, Yaffe, Michael B.
Published in Cell reports (Cambridge) (01.11.2013)
Published in Cell reports (Cambridge) (01.11.2013)
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Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel
Liu, Fa, Park, Jung-Eun, Qian, Wen-Jian, Lim, Dan, Gräber, Martin, Berg, Thorsten, Yaffe, Michael B, Lee, Kyung S, Burke, Terrence R
Published in Nature chemical biology (17.07.2011)
Published in Nature chemical biology (17.07.2011)
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Transite: A Computational Motif-Based Analysis Platform That Identifies RNA-Binding Proteins Modulating Changes in Gene Expression
Krismer, Konstantin, Bird, Molly A., Varmeh, Shohreh, Handly, Erika D., Gattinger, Anna, Bernwinkler, Thomas, Anderson, Daniel A., Heinzel, Andreas, Joughin, Brian A., Kong, Yi Wen, Cannell, Ian G., Yaffe, Michael B.
Published in Cell reports (Cambridge) (25.08.2020)
Published in Cell reports (Cambridge) (25.08.2020)
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Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: A comparison of the X-ray crystal structures of all human 14-3-3 isoforms
Gardino, Alexandra K., Smerdon, Stephen J., Yaffe, Michael B.
Published in Seminars in cancer biology (01.06.2006)
Published in Seminars in cancer biology (01.06.2006)
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Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints
Kong, Yi Wen, Dreaden, Erik C., Morandell, Sandra, Zhou, Wen, Dhara, Sanjeev S., Sriram, Ganapathy, Lam, Fred C., Patterson, Jesse C., Quadir, Mohiuddin, Dinh, Anh, Shopsowitz, Kevin E., Varmeh, Shohreh, Yilmaz, Ömer H., Lippard, Stephen J., Reinhardt, H. Christian, Hemann, Michael T., Hammond, Paula T., Yaffe, Michael B.
Published in Nature communications (17.08.2020)
Published in Nature communications (17.08.2020)
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Activation of the Yeast Hippo Pathway by Phosphorylation-Dependent Assembly of Signaling Complexes
Rock, Jeremy M., Lim, Daniel, Stach, Lasse, Ogrodowicz, Roksana W., Keck, Jamie M., Jones, Michele H., Wong, Catherine C. L., Yates, John R., Winey, Mark, Smerdon, Stephen J., Yaffe, Michael B., Amon, Angelika
Published in Science (American Association for the Advancement of Science) (17.05.2013)
Published in Science (American Association for the Advancement of Science) (17.05.2013)
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Modeling chemotherapy-induced stress to identify rational combination therapies in the DNA damage response pathway
Alkan, Ozan, Schoeberl, Birgit, Shah, Millie, Koshkaryev, Alexander, Heinemann, Tim, Drummond, Daryl C, Yaffe, Michael B, Raue, Andreas
Published in Science signaling (24.07.2018)
Published in Science signaling (24.07.2018)
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Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs
van de Kooij, Bert, Creixell, Pau, van Vlimmeren, Anne, Joughin, Brian A, Miller, Chad J, Haider, Nasir, Simpson, Craig D, Linding, Rune, Stambolic, Vuk, Turk, Benjamin E, Yaffe, Michael B
Published in eLife (24.05.2019)
Published in eLife (24.05.2019)
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Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate
Lowery, Drew M, Clauser, Karl R, Hjerrild, Majbrit, Lim, Dan, Alexander, Jes, Kishi, Kazuhiro, Ong, Shao-En, Gammeltoft, Steen, Carr, Steven A, Yaffe, Michael B
Published in The EMBO journal (02.05.2007)
Published in The EMBO journal (02.05.2007)
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Exploiting synthetic lethal interactions for targeted cancer therapy
Reinhardt, H. Christian, Jiang, Hai, Hemann, Michael T., Yaffe, Michael B.
Published in Cell cycle (Georgetown, Tex.) (01.10.2009)
Published in Cell cycle (Georgetown, Tex.) (01.10.2009)
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