Bouchardatine analogue alleviates non‐alcoholic hepatic fatty liver disease/non‐alcoholic steatohepatitis in high‐fat fed mice by inhibiting ATP synthase activity
Rao, Yong, Lu, Yu‐Ting, Li, Chan, Song, Qin‐Qin, Xu, Yao‐Hao, Xu, Zhao, Hu, Yu‐Tao, Yu, Hong, Gao, Lin, Gu, Lian‐Quan, Ye, Ji‐Ming, Huang, Zhi‐Shu
Published in British journal of pharmacology (01.08.2019)
Published in British journal of pharmacology (01.08.2019)
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A novel HSF1 activator ameliorates non‐alcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation
Rao, Yong, Li, Chan, Hu, Yu‐Tao, Xu, Yao‐Hao, Song, Bing‐Bing, Guo, Shi‐Yao, Jiang, Zhi, Zhao, Dan‐Dan, Chen, Shuo‐Bin, Tan, Jia‐Heng, Huang, Shi‐Liang, Li, Qing‐Jiang, Wang, Xiao‐Jun, Zhang, Ying‐Jun, Ye, Ji‐Ming, Huang, Zhi‐Shu
Published in British journal of pharmacology (01.04.2022)
Published in British journal of pharmacology (01.04.2022)
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Fluorescent Quinolinium Derivative as Novel Mitochondria Probe and Function Modulator by Targeting Mitochondrial RNA
Wang, Bo-Zheng, Zhou, Ying-Chen, Lin, Yu-Wei, Chen, Xiu-Cai, Yu, Ze-Yi, Xu, Yao-Hao, Tan, Jia-Heng, Huang, Zhi-Shu, Chen, Shuo-Bin
Published in Molecules (Basel, Switzerland) (01.03.2023)
Published in Molecules (Basel, Switzerland) (01.03.2023)
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Journal Article
Matrine counteracts obesity in mice via inducing adipose thermogenesis by activating HSF1/PGC-1α axis
Li, Chan, Xu, Yao-Hao, Hu, Yu-Tao, Zhou, Xiu, Huang, Zhi-Shu, Ye, Ji-Ming, Rao, Yong
Published in Pharmacological research (01.03.2022)
Published in Pharmacological research (01.03.2022)
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New Disubstituted Quindoline Derivatives Inhibiting Burkitt’s Lymphoma Cell Proliferation by Impeding c‑MYC Transcription
Liu, Hui-Yun, Chen, Ai-Chun, Yin, Qi-Kun, Li, Zeng, Huang, Su-Mei, Du, Gang, He, Jin-Hui, Zan, Li-Peng, Wang, Shi-Ke, Xu, Yao-Hao, Tan, Jia-Heng, Ou, Tian-Miao, Li, Ding, Gu, Lian-Quan, Huang, Zhi-Shu
Published in Journal of medicinal chemistry (13.07.2017)
Published in Journal of medicinal chemistry (13.07.2017)
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Palladium oxidative addition complex-enabled synthesis of amino-substituted indolyl-4(3 H )-quinazolinones and their antitumor activity evaluation
Jiang, Zhi, Zhao, Dan-Dan, Hu, Yu-Tao, Rao, Yong, Guo, Shi-Yao, Xu, Yao-Hao, Li, Qingjiang, Huang, Zhi-Shu
Published in Organic & biomolecular chemistry (19.01.2022)
Published in Organic & biomolecular chemistry (19.01.2022)
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Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors
Wang, Chen-Xi, Zhang, Zi-Lin, Yin, Qi-Kun, Tu, Jia-Li, Wang, Jia-En, Xu, Yao-Hao, Rao, Yong, Ou, Tian-Miao, Huang, Shi-Liang, Li, Ding, Wang, Hong-Gen, Li, Qing-Jiang, Tan, Jia-Heng, Chen, Shuo-Bin, Huang, Zhi-Shu
Published in Journal of medicinal chemistry (10.09.2020)
Published in Journal of medicinal chemistry (10.09.2020)
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Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism
Guo, Shi-Yao, Wei, Li-Yuan, Song, Bing-Bing, Hu, Yu-Tao, Jiang, Zhi, Zhao, Dan-Dan, Xu, Yao-Hao, Lin, Yu-Wei, Xu, Shu-Min, Chen, Shuo-Bin, Huang, Zhi-Shu
Published in European journal of medicinal chemistry (15.11.2023)
Published in European journal of medicinal chemistry (15.11.2023)
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Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal Cancer
Xu, Yao-Hao, Hu, Yu-Tao, Xu, Shu-Min, Song, Bing-Bing, Yuan, Hao, Zhao, Dan-Dan, Guo, Shi-Yao, Jiang, Zhi, Wei, Li-Yuan, Rao, Yong, Tan, Jia-Heng, Huang, Shi-Liang, Li, Qing-Jiang, Chen, Shuo-Bin, Huang, Zhi-Shu
Published in Journal of medicinal chemistry (08.06.2023)
Published in Journal of medicinal chemistry (08.06.2023)
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Bouchardatine suppresses rectal cancer in mice by disrupting its metabolic pathways via activating the SIRT1-PGC-1α-UCP2 axis
Xu, Yao-Hao, Song, Qin-Qin, Li, Chan, Hu, Yu-Tao, Song, Bing-Bing, Ye, Ji-Ming, Rao, Yong, Huang, Zhi-Shu
Published in European journal of pharmacology (05.07.2019)
Published in European journal of pharmacology (05.07.2019)
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Journal Article
Discovery of a promising agent IQZ23 for the treatment of obesity and related metabolic disorders
Rao, Yong, Xu, Zhao, Hu, Yu-Tao, Li, Chan, Xu, Yao-Hao, Song, Qin-Qin, Yu, Hong, Song, Bing-Bing, Chen, Shuo-Bin, Li, Qing-Jiang, Huang, Shi-Liang, Tan, Jia-Heng, Ou, Tian-Miao, Wang, Hong-Gen, Zhong, Guo-Ping, Ye, Ji-Ming, Huang, Zhi-Shu
Published in European journal of medicinal chemistry (15.04.2020)
Published in European journal of medicinal chemistry (15.04.2020)
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Pyridocarbazole alkaloids from Ochrosia borbonica: lipid-lowering agents inhibit the cell proliferation and adipogenesis of 3T3-L1 adipocyte via intercalating into supercoiled DNA
XU, Yao-Hao, LI, Wei, RAO, Yong, HUANG, Zhi-Shu, YIN, Sheng
Published in Chinese journal of natural medicines (01.09.2019)
Published in Chinese journal of natural medicines (01.09.2019)
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Journal Article
Design, synthesis and biological evaluation of novel bouchardatine analogs as potential inhibitors of adipogenesis/lipogenesis in 3T3-L1 adipocytes
Gao, Lin, Xu, Zhao, Rao, Yong, Lu, Yu-Ting, Hu, Yu-Tao, Yu, Hong, Xu, Yao-Hao, Song, Qing-Qing, Ye, Ji-Ming, Huang, Zhi-Shu
Published in European journal of medicinal chemistry (10.03.2018)
Published in European journal of medicinal chemistry (10.03.2018)
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