Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module
Arce, Nicholas A., Cao, Wenpeng, Brown, Alexander K., Legan, Emily R., Wilson, Moriah S., Xu, Emma-Ruoqi, Berndt, Michael C., Emsley, Jonas, Zhang, X. Frank, Li, Renhao
Published in Nature communications (21.04.2021)
Published in Nature communications (21.04.2021)
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The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction
Schneppenheim, Reinhard, Hellermann, Natalie, Brehm, Maria A., Klemm, Ulrike, Obser, Tobias, Huck, Volker, Schneider, Stefan W., Denis, Cécile V., Tischer, Alexander, Auton, Matthew, März, Winfried, Xu, Emma-Ruoqi, Wilmanns, Matthias, Zotz, Rainer B.
Published in Blood (24.01.2019)
Published in Blood (24.01.2019)
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The thrombospondin module 1 domain of the matricellular protein CCN3 shows an atypical disulfide pattern and incomplete CWR layers
Xu, Emma Ruoqi, Lafita, Aleix, Bateman, Alex, Hyvönen, Marko
Published in Acta crystallographica. Section D, Biological crystallography. (01.02.2020)
Published in Acta crystallographica. Section D, Biological crystallography. (01.02.2020)
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Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2
Xu, Emma-Ruoqi, Blythe, Emily E., Fischer, Gerhard, Hyvönen, Marko
Published in The Journal of biological chemistry (28.07.2017)
Published in The Journal of biological chemistry (28.07.2017)
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Structural assessment of SARS-CoV2 accessory protein ORF7a predicts LFA-1 and Mac-1 binding potential
Nizamudeen, Zubair Ahmed, Xu, Emma-Ruoqi, Karthik, Vivin, Halawa, Mohamed, Arkill, Kenton P, Jackson, Andrew M, Bates, David O, Emsley, Jonas
Published in Bioscience reports (29.01.2021)
Published in Bioscience reports (29.01.2021)
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Structure and dynamics of the von Willebrand Factor C6 domain
Chen, Po-chia, Kutzki, Fabian, Mojzisch, Angelika, Simon, Bernd, Xu, Emma-Ruoqi, Aponte-Santamaría, Camilo, Horny, Kai, Jeffries, Cy, Schneppenheim, Reinhard, Wilmanns, Matthias, Brehm, Maria A., Gräter, Frauke, Hennig, Janosch
Published in Journal of structural biology (01.12.2022)
Published in Journal of structural biology (01.12.2022)
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Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor
Xu, Emma-Ruoqi, von Bülow, Sören, Chen, Po-Chia, Lenting, Peter J., Kolšek, Katra, Aponte-Santamaría, Camilo, Simon, Bernd, Foot, Jaelle, Obser, Tobias, Schneppenheim, Reinhard, Gräter, Frauke, Denis, Cécile V., Wilmanns, Matthias, Hennig, Janosch
Published in Blood (24.01.2019)
Published in Blood (24.01.2019)
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Gain-of-Function Variant p.Pro2555Arg of von Willebrand Factor Increases Aggregate Size through Altering Stem Dynamics
Huck, Volker, Chen, Po-Chia, Xu, Emma-Ruoqi, Tischer, Alexander, Klemm, Ulrike, Aponte-Santamaría, Camilo, Mess, Christian, Obser, Tobias, Kutzki, Fabian, König, Gesa, Denis, Cécile V., Gräter, Frauke, Wilmanns, Matthias, Auton, Matthew, Schneider, Stefan W., Schneppenheim, Reinhard, Hennig, Janosch, Brehm, Maria A.
Published in Thrombosis and haemostasis (01.02.2022)
Published in Thrombosis and haemostasis (01.02.2022)
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The Von Willebrand Factor Tyr2561 Allele Is a Gain-of-Function Variant and a Potential Risk Factor for Early Myocardial Infarction
Schneppenheim, Reinhard, Hellermann, Natalie, Brehm, Maria Alexandra, Klemm, Ulrike, Obser, Tobias, Huck, Volker, Schneider, Stefan W, Denis, Cecile V., Tischer, Alexander, Auton, Matthew, Maerz, Winfried, Xu, Emma-Ruoqi, Wilmanns, Matthias, Zotz, Rainer B.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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