Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis
Lv, Jian-Ming, Hu, Dan, Gao, Hao, Kushiro, Tetsuo, Awakawa, Takayoshi, Chen, Guo-Dong, Wang, Chuan-Xi, Abe, Ikuro, Yao, Xin-Sheng
Published in Nature communications (21.11.2017)
Published in Nature communications (21.11.2017)
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Biosynthesis of Biscognienyne B Involving a Cytochrome P450‐Dependent Alkynylation
Lv, Jian‐Ming, Gao, Yao‐Hui, Zhao, Huan, Awakawa, Takayoshi, Liu, Ling, Chen, Guo‐Dong, Yao, Xin‐Sheng, Hu, Dan, Abe, Ikuro, Gao, Hao
Published in Angewandte Chemie International Edition (03.08.2020)
Published in Angewandte Chemie International Edition (03.08.2020)
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Fuziline alleviates isoproterenol‐induced myocardial injury by inhibiting ROS‐triggered endoplasmic reticulum stress via PERK/eIF2α/ATF4/Chop pathway
Fan, Cai‐lian, Yao, Zhi‐hong, Ye, Meng‐nan, Fu, Lei‐lei, Zhu, Guo‐nian, Dai, Yi, Yao, Xin‐sheng
Published in Journal of cellular and molecular medicine (01.01.2020)
Published in Journal of cellular and molecular medicine (01.01.2020)
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Delivering Crocetin across the Blood-Brain Barrier by Using γ-Cyclodextrin to Treat Alzheimer's Disease
Wong, Ka Hong, Xie, Yuning, Huang, Xiao, Kadota, Kazunori, Yao, Xin-Sheng, Yu, Yang, Chen, Xiaoyu, Lu, Aiping, Yang, Zhijun
Published in Scientific reports (27.02.2020)
Published in Scientific reports (27.02.2020)
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Development of a versatile and conventional technique for gene disruption in filamentous fungi based on CRISPR-Cas9 technology
Zheng, Yan-Mei, Lin, Fu-Long, Gao, Hao, Zou, Gen, Zhang, Jiang-Wei, Wang, Gao-Qian, Chen, Guo-Dong, Zhou, Zhi-Hua, Yao, Xin-Sheng, Hu, Dan
Published in Scientific reports (23.08.2017)
Published in Scientific reports (23.08.2017)
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Activation of Nrf2/HO-1 Pathway by Nardochinoid C Inhibits Inflammation and Oxidative Stress in Lipopolysaccharide-Stimulated Macrophages
Luo, Jin-Fang, Shen, Xiu-Yu, Lio, Chon Kit, Dai, Yi, Cheng, Chun-Song, Liu, Jian-Xin, Yao, Yun-Da, Yu, Yang, Xie, Ying, Luo, Pei, Yao, Xin-Sheng, Liu, Zhong-Qiu, Zhou, Hua
Published in Frontiers in pharmacology (04.09.2018)
Published in Frontiers in pharmacology (04.09.2018)
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Biosynthetic pathway for furanosteroid demethoxyviridin and identification of an unusual pregnane side-chain cleavage
Wang, Gao-Qian, Chen, Guo-Dong, Qin, Sheng-Ying, Hu, Dan, Awakawa, Takayoshi, Li, Shao-Yang, Lv, Jian-Ming, Wang, Chuan-Xi, Yao, Xin-Sheng, Abe, Ikuro, Gao, Hao
Published in Nature communications (09.05.2018)
Published in Nature communications (09.05.2018)
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Pharmacokinetics, hepatic disposition, and heart tissue distribution of 14 compounds in rat after oral administration of Qi‐Li‐Qiang‐Xin capsule via ultra‐high‐performance liquid chromatography coupled with triple quadrupole tandem mass spectrometry
Tang, Xi‐Yang, Dai, Zi‐Qin, Zeng, Jia‐Xing, Li, Zi‐Ting, Fan, Cai‐Lian, Yao, Zhi‐Hong, Yao, Xin‐Sheng, Dai, Yi
Published in Journal of separation science (01.07.2022)
Published in Journal of separation science (01.07.2022)
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Sporormielones A-E, bioactive novel C-C coupled orsellinic acid derivative dimers, and their biosynthetic origin
Chen, Guo-Dong, Hu, Dan, Huang, Mei-Juan, Tang, Jia, Wang, Xiao-Xia, Zou, Jian, Xie, Jun, Zhang, Wei-Guang, Guo, Liang-Dong, Yao, Xin-Sheng, Abe, Ikuro, Gao, Hao
Published in Chemical communications (Cambridge, England) (28.04.2020)
Published in Chemical communications (Cambridge, England) (28.04.2020)
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An integrated strategy by absorbed component characterization, pharmacokinetics, and activity evaluation for identification of potential nephroprotective substances in Zhu‐Ling decoction
Shu, Zhi‐heng, Fan, Cai‐lian, Wei, Hong‐yan, Li, Zi‐ting, Norimoto, Hisayoshi, Tang, Xi‐yang, Yao, Zhi‐hong, Yao, Xin‐sheng, Dai, Yi
Published in Journal of separation science (01.09.2023)
Published in Journal of separation science (01.09.2023)
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Biosynthetic characterization of the antifungal fernane-type triterpenoid polytolypin for generation of new analogues via combinatorial biosynthesis
Li, Xin-Yu, Lv, Jian-Ming, Cao, Zhi-Qin, Wang, Gao-Qian, Lin, Fu-Long, Chen, Guo-Dong, Qin, Sheng-Ying, Hu, Dan, Gao, Hao, Yao, Xin-Sheng
Published in Organic & biomolecular chemistry (25.01.2023)
Published in Organic & biomolecular chemistry (25.01.2023)
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Discovery of the mechanisms and major bioactive compounds responsible for the protective effects of Gualou Xiebai Decoction on coronary heart disease by network pharmacology analysis
Li, Chong, Zhang, Wei-Yang, Yu, Yang, Cheng, Chun-Song, Han, Jing-Yan, Yao, Xin-Sheng, Zhou, Hua
Published in Phytomedicine (Stuttgart) (15.03.2019)
Published in Phytomedicine (Stuttgart) (15.03.2019)
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Nur77 Serves as a Potential Prognostic Biomarker That Correlates with Immune Infiltration and May Act as a Good Target for Prostate adenocarcinoma
Hu, Qiong-Ying, Liu, Jie, Zhang, Xiao-Kun, Yang, Wan-Ting, Tao, Yu-Tian, Chen, Ce, Qian, Ye-He, Tang, Jin-Shan, Yao, Xin-Sheng, Xu, Ying-He, Wang, Jing-Hui
Published in Molecules (Basel, Switzerland) (28.01.2023)
Published in Molecules (Basel, Switzerland) (28.01.2023)
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Isolation of new compounds related to xyloketals biosynthesis implies an alternative pathway for furan-fused-chromene formation
Huang, Jia-Hua, Lv, Jian-Ming, Xie, Yan-Feng, Zhao, Huan, Xiao, Liang-Yan, Dai, Ping, Qin, Sheng-Ying, Hu, Dan, Gao, Hao, Yao, Xin-Sheng
Published in Organic & biomolecular chemistry (24.05.2023)
Published in Organic & biomolecular chemistry (24.05.2023)
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Biosynthesis of an anti- tuberculosis sesterterpenoid asperterpenoid A
Huang, Jia-Hua, Lv, Jian-Ming, Wang, Qiao-Zhen, Zou, Jian, Lu, Yong-Jun, Wang, Qing-Lin, Chen, Dong-Ni, Yao, Xin-Sheng, Gao, Hao, Hu, Dan
Published in Organic & biomolecular chemistry (02.01.2019)
Published in Organic & biomolecular chemistry (02.01.2019)
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Baphicacanthcusines A–E, Bisindole Alkaloids from the Leaves of Baphicacanthus cusia (Nees) Bremek
Zhu, Ling-Juan, Cao, Fei, Su, Xiang-Xin, Li, Chun-Yu, Lin, Bin, Wang, Hai-Feng, Yao, Xin-Sheng, Zhang, Xue, Jia, Jing-Ming, Liu, Hong-Wei
Published in Journal of organic chemistry (02.07.2020)
Published in Journal of organic chemistry (02.07.2020)
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Nardochinoid B Inhibited the Activation of RAW264.7 Macrophages Stimulated by Lipopolysaccharide through Activating the Nrf2/HO-1 Pathway
Yao, Yun-Da, Shen, Xiu-Yu, Machado, Jorge, Luo, Jin-Fang, Dai, Yi, Lio, Chon-Kit, Yu, Yang, Xie, Ying, Luo, Pei, Liu, Jian-Xin, Yao, Xin-Sheng, Liu, Zhong-Qiu, Zhou, Hua
Published in Molecules (Basel, Switzerland) (06.07.2019)
Published in Molecules (Basel, Switzerland) (06.07.2019)
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Triangeliphthalides A-D: bioactive phthalide trimers with new skeletons from Angelica sinensis and their production mechanism
Zou, Jian, Chen, Guo-Dong, Zhao, Huan, Wang, Xiao-Xia, Zhang, Zai-Jun, Qu, Yi-Bo, He, Rong-Rong, So, Kwok-Fai, Yao, Xin-Sheng, Gao, Hao
Published in Chemical communications (Cambridge, England) (28.05.2019)
Published in Chemical communications (Cambridge, England) (28.05.2019)
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