SWELL1 is a glucose sensor regulating β-cell excitability and systemic glycaemia
Kang, Chen, Xie, Litao, Gunasekar, Susheel K, Mishra, Anil, Zhang, Yanhui, Pai, Saachi, Gao, Yiwen, Kumar, Ashutosh, Norris, Andrew W, Stephens, Samuel B, Sah, Rajan
Published in Nature communications (25.01.2018)
Published in Nature communications (25.01.2018)
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Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes
Gunasekar, Susheel K, Xie, Litao, Kumar, Ashutosh, Hong, Juan, Chheda, Pratik R, Kang, Chen, Kern, David M, My-Ta, Chau, Maurer, Joshua, Heebink, John, Gerber, Eva E, Grzesik, Wojciech J, Elliot-Hudson, Macaulay, Zhang, Yanhui, Key, Phillip, Kulkarni, Chaitanya A, Beals, Joseph W, Smith, Gordon I, Samuel, Isaac, Smith, Jessica K, Nau, Peter, Imai, Yumi, Sheldon, Ryan D, Taylor, Eric B, Lerner, Daniel J, Norris, Andrew W, Klein, Samuel, Brohawn, Stephen G, Kerns, Robert, Sah, Rajan
Published in Nature communications (10.02.2022)
Published in Nature communications (10.02.2022)
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The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function
Alghanem, Ahmad F, Abello, Javier, Maurer, Joshua M, Kumar, Ashutosh, Ta, Chau My, Gunasekar, Susheel K, Fatima, Urooj, Kang, Chen, Xie, Litao, Adeola, Oluwaseun, Riker, Megan, Elliot-Hudson, Macaulay, Minerath, Rachel A, Grueter, Chad E, Mullins, Robert F, Stratman, Amber N, Sah, Rajan
Published in eLife (25.02.2021)
Published in eLife (25.02.2021)
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SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism
Kumar, Ashutosh, Xie, Litao, Ta, Chau My, Hinton, Antentor O, Gunasekar, Susheel K, Minerath, Rachel A, Shen, Karen, Maurer, Joshua M, Grueter, Chad E, Abel, E Dale, Meyer, Gretchen, Sah, Rajan
Published in eLife (15.09.2020)
Published in eLife (15.09.2020)
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Journal Article
Adipose-targeted SWELL1 deletion exacerbates obesity- and age-related nonalcoholic fatty liver disease
Gunasekar, Susheel K, Heebink, John, Carpenter, Danielle H, Kumar, Ashutosh, Xie, Litao, Zhang, Haixia, Schilling, Joel D, Sah, Rajan
Published in JCI insight (08.03.2023)
Published in JCI insight (08.03.2023)
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The multifunctional Ca2+/calmodulin-dependent kinase II regulates vascular smooth muscle migration through matrix metalloproteinase 9
Scott, Jason A, Xie, Litao, Li, Hui, Li, Weiwei, He, Julie B, Sanders, Philip N, Carter, A Brent, Backs, Johannes, Anderson, Mark E, Grumbach, Isabella M
Published in American journal of physiology. Heart and circulatory physiology (15.05.2012)
Published in American journal of physiology. Heart and circulatory physiology (15.05.2012)
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Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription
Pennington, Steven M., Klutho, Paula R., Xie, Litao, Broadhurst, Kim, Koval, Olha M., McCormick, Michael L., Spitz, Douglas R., Grumbach, Isabella M.
Published in Redox biology (01.06.2018)
Published in Redox biology (01.06.2018)
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Oxidative activation of the Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates vascular smooth muscle migration and apoptosis
Zhu, Linda J., Klutho, Paula J., Scott, Jason A., Xie, Litao, Luczak, Elizabeth D., Dibbern, Megan E., Prasad, Anand M., Jaffer, Omar A., Venema, Ashlee N., Nguyen, Emily K., Guan, Xiaoqun, Anderson, Mark E., Grumbach, Isabella M.
Published in Vascular pharmacology (01.02.2014)
Published in Vascular pharmacology (01.02.2014)
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The multifunctional Ca²⁺/calmodulin-dependent kinase IIδ (CaMKIIδ) regulates arteriogenesis in a mouse model of flow-mediated remodeling
Scott, Jason A, Klutho, Paula J, El Accaoui, Ramzi, Nguyen, Emily, Venema, Ashlee N, Xie, Litao, Jiang, Shuxia, Dibbern, Megan, Scroggins, Sabrina, Prasad, Anand M, Luczak, Elisabeth D, Davis, Melissa K, Li, Weiwei, Guan, Xiaoqun, Backs, Johannes, Schlueter, Annette J, Weiss, Robert M, Miller, Francis J, Anderson, Mark E, Grumbach, Isabella M
Published in PloS one (08.08.2013)
Published in PloS one (08.08.2013)
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Persistent expression of factor VIII in vivo following nonprimate lentiviral gene transfer
Kang, Yubin, Xie, Litao, Tran, Diane Thi, Stein, Colleen S., Hickey, Melissa, Davidson, Beverly L., McCray, Paul B.
Published in Blood (01.09.2005)
Published in Blood (01.09.2005)
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Integration Site Choice of a Feline Immunodeficiency Virus Vector
YUBIN KANG, MORESSI, Christopher J, SCHEETZ, Todd E, LITAO XIE, DIANE THI TRAN, CASAVANT, Thomas L, AK, Prashanth, BENHAM, Craig J, DAVIDSON, Beverly L, MCCRAY, Paul B
Published in Journal of Virology (01.09.2006)
Published in Journal of Virology (01.09.2006)
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Journal Article
SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis
Zhang, Yanhui, Xie, Litao, Gunasekar, Susheel K, Tong, Dan, Mishra, Anil, Gibson, William J, Wang, Chuansong, Fidler, Trevor, Marthaler, Brodie, Klingelhutz, Aloysius, Abel, E Dale, Samuel, Isaac, Smith, Jessica K, Cao, Lei, Sah, Rajan
Published in Nature cell biology (01.05.2017)
Published in Nature cell biology (01.05.2017)
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Abstract 119: LRRC8 Complex Is An ATP Release Channel Regulating Platelet Activation And Thrombosis
Tranter, John D, Kumar, Ashutosh, Brown, Gavriel, Mikami, Ryan, Zhao, Yonghui, Abraham, Nihil, Abd El-Aziz, Tarek M, Ajanel, Abigail, Xie, Litao, Ashworth, Katrina, Hong, Juan, Zhang, Haixia, Kumari, Tripti, Liu, Alice, Balutowski, Adam, Nair, Vinayak K, Lasky, Nina M, Feng, Yongmei, Stitziel, Nathan O, Lerner, Daniel J, Campbell, Robert A, Di Paola, Jorge, Cho, Jaehyung, Sah, Rajan
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2024)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2024)
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Journal Article
The Swell1-LRRC8 Complex Regulates Endothelial PI3K-AKT2-GRB2-eNOS Signaling and Vascular Function
Alghanem, Ahmad F., Ta, Chau, Adeola, Oluwaseun, Gunasekar, Susheel K., Fatima, Urooj, Elliot-Hudson, Elliot-Hudson, Zhang, Yanhui, Riker, Megan, Mullins, Robert F., Xie, Litao, Sah, Rajan
Published in Biophysical journal (15.02.2019)
Published in Biophysical journal (15.02.2019)
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Abstract 524: Deletion of Methionine Sulfoxide Reductase A in Mice Increases Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia
Klutho, Paula J, Scott, Jason, Xie, Litao, Grumbach, Isabella M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2014)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2014)
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Journal Article
Isolation and Patch-Clamp of Primary Adipocytes
Zhang, Yanhui, Tong, Dan, Mishra, Anil, Xie, Litao, Samuel, Isaac, Smith, Jessica K, Sah, Rajan
Published in Methods in molecular biology (Clifton, N.J.) (2017)
Published in Methods in molecular biology (Clifton, N.J.) (2017)
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Deletion of Methionine Sulfoxide Reductase A Does Not Affect Atherothrombosis but Promotes Neointimal Hyperplasia and Extracellular Signal-Regulated Kinase 1/2 Signaling
Klutho, Paula J, Pennington, Steven M, Scott, Jason A, Wilson, Katina M, Gu, Sean X, Doddapattar, Prakash, Xie, Litao, Venema, Ashlee N, Zhu, Linda J, Chauhan, Anil K, Lentz, Steven R, Grumbach, Isabella M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2015)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2015)
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Erratum: SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis
Zhang, Yanhui, Xie, Litao, Gunasekar, Susheel K, Tong, Dan, Mishra, Anil, Gibson, William J, Wang, Chuansong, Fidler, Trevor, Marthaler, Brodie, Klingelhutz, Aloysius, Abel, E Dale, Samuel, Isaac, Smith, Jessica K, Cao, Lei, Sah, Rajan
Published in Nature cell biology (01.07.2017)
Published in Nature cell biology (01.07.2017)
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