STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism
Xian, Hongxu, Yang, Qiaoyun, Xiao, Lin, Shen, Han-Ming, Liou, Yih-Cherng
Published in Nature communications (03.05.2019)
Published in Nature communications (03.05.2019)
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Journal Article
Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling
Xian, Hongxu, Watari, Kosuke, Sanchez-Lopez, Elsa, Offenberger, Joseph, Onyuru, Janset, Sampath, Harini, Ying, Wei, Hoffman, Hal M., Shadel, Gerald S., Karin, Michael
Published in Immunity (Cambridge, Mass.) (09.08.2022)
Published in Immunity (Cambridge, Mass.) (09.08.2022)
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Journal Article
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation
Xian, Hongxu, Liu, Yuan, Rundberg Nilsson, Alexandra, Gatchalian, Raphaella, Crother, Timothy R., Tourtellotte, Warren G., Zhang, Yi, Aleman-Muench, German R., Lewis, Gavin, Chen, Weixuan, Kang, Sarah, Luevanos, Melissa, Trudler, Dorit, Lipton, Stuart A., Soroosh, Pejman, Teijaro, John, de la Torre, Juan Carlos, Arditi, Moshe, Karin, Michael, Sanchez-Lopez, Elsa
Published in Immunity (Cambridge, Mass.) (13.07.2021)
Published in Immunity (Cambridge, Mass.) (13.07.2021)
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Journal Article
Death-associated Protein 3 Regulates Mitochondrial-encoded Protein Synthesis and Mitochondrial Dynamics
Xiao, Lin, Xian, Hongxu, Lee, Kit Yee, Xiao, Bin, Wang, Hongyan, Yu, Fengwei, Shen, Han-Ming, Liou, Yih-Cherng
Published in The Journal of biological chemistry (09.10.2015)
Published in The Journal of biological chemistry (09.10.2015)
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Journal Article
IRF1 regulates self-renewal and stress-responsiveness to support hematopoietic stem cell maintenance
Rundberg Nilsson, Alexandra, Xian, Hongxu, Shalapour, Shabnam, Cammenga, Jörg, Karin, Michael
Published in bioRxiv (02.03.2023)
Published in bioRxiv (02.03.2023)
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Paper
FEN1-generated oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling
Xian, Hongxu, Watari, Kosuke, Sanchez-Lopez, Elsa, Offenberger, Joseph, Onyuru, Janset, Sampath, Harini, Ying, Wei, Hoffman, Hal M., Shadel, Gerald S., Karin, Michael
Published in Immunity (Cambridge, Mass.) (13.07.2022)
Published in Immunity (Cambridge, Mass.) (13.07.2022)
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Journal Article