Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression
De Boeck, Astrid, Ahn, Bo Young, D’Mello, Charlotte, Lun, Xueqing, Menon, Shyam V., Alshehri, Mana M., Szulzewsky, Frank, Shen, Yaoqing, Khan, Lubaba, Dang, Ngoc Ha, Reichardt, Elliott, Goring, Kimberly-Ann, King, Jennifer, Grisdale, Cameron J., Grinshtein, Natalie, Hambardzumyan, Dolores, Reilly, Karlyne M., Blough, Michael D., Cairncross, J. Gregory, Yong, V. Wee, Marra, Marco A., Jones, Steven J. M., Kaplan, David R., McCoy, Kathy D., Holland, Eric C., Bose, Pinaki, Chan, Jennifer A., Robbins, Stephen M., Senger, Donna L.
Published in Nature communications (05.10.2020)
Published in Nature communications (05.10.2020)
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Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma
Beug, Shawn T., Beauregard, Caroline E., Healy, Cristin, Sanda, Tarun, St-Jean, Martine, Chabot, Janelle, Walker, Danielle E., Mohan, Aditya, Earl, Nathalie, Lun, Xueqing, Senger, Donna L., Robbins, Stephen M., Staeheli, Peter, Forsyth, Peter A., Alain, Tommy, LaCasse, Eric C., Korneluk, Robert G.
Published in Nature communications (15.02.2017)
Published in Nature communications (15.02.2017)
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Journal Article
Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells
Sarkar, Susobhan, Döring, Axinia, Zemp, Franz J, Silva, Claudia, Lun, Xueqing, Wang, Xiuling, Kelly, John, Hader, Walter, Hamilton, Mark, Mercier, Philippe, Dunn, Jeff F, Kinniburgh, Dave, van Rooijen, Nico, Robbins, Stephen, Forsyth, Peter, Cairncross, Gregory, Weiss, Samuel, Yong, V Wee
Published in Nature neuroscience (01.01.2014)
Published in Nature neuroscience (01.01.2014)
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Novel MSH6 mutations in treatment-naïve glioblastoma and anaplastic oligodendroglioma contribute to temozolomide resistance independently of MGMT promoter methylation
Nguyen, Stephanie A, Stechishin, Owen D M, Luchman, H Artee, Lun, Xueqing Q, Senger, Donna L, Robbins, Stephen M, Cairncross, J Gregory, Weiss, Samuel
Published in Clinical cancer research (15.09.2014)
Published in Clinical cancer research (15.09.2014)
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Spatiotemporal modeling reveals high-resolution invasion states in glioblastoma
Manoharan, Varsha Thoppey, Abdelkareem, Aly, Gill, Gurveer, Brown, Samuel, Gillmor, Aaron, Hall, Courtney, Seo, Heewon, Narta, Kiran, Grewal, Sean, Dang, Ngoc Ha, Ahn, Bo Young, Osz, Kata, Lun, Xueqing, Mah, Laura, Zemp, Franz, Mahoney, Douglas, Senger, Donna L, Chan, Jennifer A, Morrissy, A Sorana
Published in Genome Biology (10.10.2024)
Published in Genome Biology (10.10.2024)
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Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments
Shen, Yaoqing, Grisdale, Cameron J., Islam, Sumaiya A., Bose, Pinaki, Lever, Jake, Zhao, Eric Y., Grinshtein, Natalie, Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Lun, Xueqing, Senger, Donna L., Robbins, Stephen M., Wang, Alice Yijun, MacIsaac, Julia L., Kobor, Michael S., Luchman, H. Artee, Weiss, Samuel, Chan, Jennifer A., Blough, Michael D., Kaplan, David R., Cairncross, J. Gregory, Marra, Marco A., Jones, Steven J. M.
Published in Proceedings of the National Academy of Sciences - PNAS (17.09.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (17.09.2019)
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macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma
Nikolic, Ana, Maule, Francesca, Bobyn, Anna, Ellestad, Katrina, Paik, Seungil, Marhon, Sajid A., Mehdipour, Parinaz, Lun, Xueqing, Chen, Huey-Miin, Mallard, Claire, Hay, Alexander J., Johnston, Michael J., Gafuik, Christopher J., Zemp, Franz J., Shen, Yaoqing, Ninkovic, Nicoletta, Osz, Katalin, Labit, Elodie, Berger, N. Daniel, Brownsey, Duncan K., Kelly, John J., Biernaskie, Jeff, Dirks, Peter B., Derksen, Darren J., Jones, Steven J. M., Senger, Donna L., Chan, Jennifer A., Mahoney, Douglas J., De Carvalho, Daniel D., Gallo, Marco
Published in Nature communications (27.05.2023)
Published in Nature communications (27.05.2023)
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Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival
Luchman, H Artee, Stechishin, Owen D M, Nguyen, Stephanie A, Lun, Xueqing Q, Cairncross, J Gregory, Weiss, Samuel
Published in Clinical cancer research (15.11.2014)
Published in Clinical cancer research (15.11.2014)
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Journal Article
Proliferation of Human Glioblastoma Stem Cells Occurs Independently of Exogenous Mitogens
Kelly, John J. P., Stechishin, Owen, Chojnacki, Andrew, Lun, Xueqing, Sun, Beichen, Senger, Donna L., Forsyth, Peter, Auer, Roland N., Dunn, Jeff F., Cairncross, J. Gregory, Parney, Ian F., Weiss, Samuel
Published in Stem cells (Dayton, Ohio) (01.08.2009)
Published in Stem cells (Dayton, Ohio) (01.08.2009)
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Journal Article
ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts
Yuan, Alice L, Ricks, Christian B, Bohm, Alexandra K, Lun, Xueqing, Maxwell, Lori, Safdar, Shahana, Bukhari, Shazreh, Gerber, Amanda, Sayeed, Wajid, Bering, Elizabeth A, Pedersen, Haley, Chan, Jennifer A, Shen, Yaoqing, Marra, Marco, Kaplan, David R, Mason, Warren, Goodman, Lindsey D, Ezhilarasan, Ravesanker, Kaufmann, Ascher B, Cabral, Matthew, Robbins, Steve M, Senger, Donna L, Cahill, Daniel P, Sulman, Erik P, Cairncross, J Gregory, Blough, Michael D
Published in PloS one (28.08.2018)
Published in PloS one (28.08.2018)
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M011L-deficient oncolytic myxoma virus induces apoptosis in brain tumor-initiating cells and enhances survival in a novel immunocompetent mouse model of glioblastoma
Pisklakova, Alexandra, McKenzie, Brienne, Zemp, Franz, Lun, Xueqing, Kenchappa, Rajappa S, Etame, Arnold B, Rahman, Masmudur M, Reilly, Karlyne, Pilon-Thomas, Shari, McFadden, Grant, Kurz, Ebba, Forsyth, Peter A
Published in Neuro-oncology (Charlottesville, Va.) (01.08.2016)
Published in Neuro-oncology (Charlottesville, Va.) (01.08.2016)
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Journal Article
Myxoma virus infection promotes NK lysis of malignant gliomas in vitro and in vivo
Ogbomo, Henry, Zemp, Franz J, Lun, Xueqing, Zhang, Jiqing, Stack, Danuta, Rahman, Masmudur M, McFadden, Grant, Mody, Christopher H, Forsyth, Peter A
Published in PloS one (10.06.2013)
Published in PloS one (10.06.2013)
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Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production
Alain, Tommy, Lun, XueQing, Martineau, Yvan, Sean, Polen, Pulendran, Bali, Petroulakis, Emmanuel, Zemp, Franz J, Lemay, Chantal G, Roy, Dominic, Bell, John C, Thomas, George, Kozma, Sara C, Forsyth, Peter A, Costa-Mattioli, Mauro, Sonenberg, Nahum
Published in Proceedings of the National Academy of Sciences - PNAS (26.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (26.01.2010)
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Journal Article
The p75 neurotrophin receptor is a central regulator of glioma invasion
Johnston, Angela L M, Lun, Xueqing, Rahn, Jennifer J, Liacini, Abdelhamid, Wang, Limei, Hamilton, Mark G, Parney, Ian F, Hempstead, Barbara L, Robbins, Stephen M, Forsyth, Peter A, Senger, Donna L
Published in PLoS biology (01.08.2007)
Published in PLoS biology (01.08.2007)
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Journal Article
Correction: Publisher Correction: Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma
Beug, Shawn T., Beauregard, Caroline E., Healy, Cristin, Sanda, Tarun, St-Jean, Martine, Chabot, Janelle, Walker, Danielle E., Mohan, Aditya, Earl, Nathalie, Lun, Xueqing, Senger, Donna L., Robbins, Stephen M., Staeheli, Peter, Forsyth, Peter A., Alain, Tommy, LaCasse, Eric C., Korneluk, Robert G.
Published in Nature communications (18.07.2018)
Published in Nature communications (18.07.2018)
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Journal Article
Myxoma virus is a novel oncolytic virus with significant antitumor activity against experimental human gliomas
XUEQING LUN, WENQING YANG, FORSYTH, Peter A, ALAIN, Tommy, SHI, Zhong-Qiao, MUZIK, Huong, BARRETT, John W, MCFADDEN, Grant, BELL, John, HAMILTON, Mark G, SENGER, Donna L
Published in Cancer research (Chicago, Ill.) (01.11.2005)
Published in Cancer research (Chicago, Ill.) (01.11.2005)
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Effects of Intravenously Administered Recombinant Vesicular Stomatitis Virus (VSVΔM51) on Multifocal and Invasive Gliomas
Lun, XueQing, Senger, Donna L., Alain, Tommy, Oprea, Andra, Parato, Kelley, Stojdl, Dave, Lichty, Brian, Power, Anthony, Johnston, Randal N., Hamilton, Mark, Parney, Ian, Bell, John C., Forsyth, Peter A.
Published in JNCI : Journal of the National Cancer Institute (01.11.2006)
Published in JNCI : Journal of the National Cancer Institute (01.11.2006)
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Journal Article
Proteolytic Disassembly Is a Critical Determinant for Reovirus Oncolysis
Alain, Tommy, Kim, Tom SY, Lun, XueQing, Liacini, Adelhamid, Schiff, Leslie A, Senger, Donna L, Forsyth, Peter A
Published in Molecular therapy (01.08.2007)
Published in Molecular therapy (01.08.2007)
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Journal Article
Gamma-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor
Wang, LiMei, Rahn, Jennifer J, Lun, XueQing, Sun, Beichen, Kelly, John J P, Weiss, Samuel, Robbins, Stephen M, Forsyth, Peter A, Senger, Donna L
Published in PLoS biology (01.11.2008)
Published in PLoS biology (01.11.2008)
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Journal Article
Resistance to oncolytic myxoma virus therapy in nf1(-/-)/trp53(-/-) syngeneic mouse glioma models is independent of anti-viral type-I interferon
Zemp, Franz J, McKenzie, Brienne A, Lun, Xueqing, Maxwell, Lori, Reilly, Karlyne M, McFadden, Grant, Yong, V Wee, Forsyth, Peter A
Published in PloS one (06.06.2013)
Published in PloS one (06.06.2013)
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