Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis
Ruhland, Megan K., Loza, Andrew J., Capietto, Aude-Helene, Luo, Xianmin, Knolhoff, Brett L., Flanagan, Kevin C., Belt, Brian A., Alspach, Elise, Leahy, Kathleen, Luo, Jingqin, Schaffer, Andras, Edwards, John R., Longmore, Gregory, Faccio, Roberta, DeNardo, David G., Stewart, Sheila A.
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Published in Nature communications (08.06.2016)
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Therapy-Induced Senescence Drives Bone Loss
Yao, Zhangting, Murali, Bhavna, Ren, Qihao, Luo, Xianmin, Faget, Douglas V, Cole, Tom, Ricci, Biancamaria, Thotala, Dinesh, Monahan, Joseph, van Deursen, Jan M, Baker, Darren, Faccio, Roberta, Schwarz, Julie K, Stewart, Sheila A
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Published in Cancer research (Chicago, Ill.) (01.03.2020)
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p38MAPK plays a crucial role in stromal-mediated tumorigenesis
Alspach, Elise, Flanagan, Kevin C, Luo, Xianmin, Ruhland, Megan K, Huang, Hui, Pazolli, Ermira, Donlin, Maureen J, Marsh, Timothy, Piwnica-Worms, David, Monahan, Joseph, Novack, Deborah V, McAllister, Sandra S, Stewart, Sheila A
Published in Cancer discovery (01.06.2014)
Published in Cancer discovery (01.06.2014)
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Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development
Luo, Xianmin, Fu, Yujie, Loza, Andrew J., Murali, Bhavna, Leahy, Kathleen M., Ruhland, Megan K., Gang, Margery, Su, Xinming, Zamani, Ali, Shi, Yu, Lavine, Kory J., Ornitz, David M., Weilbaecher, Katherine N., Long, Fanxin, Novack, Deborah V., Faccio, Roberta, Longmore, Gregory D., Stewart, Sheila A.
Published in Cell reports (Cambridge) (05.01.2016)
Published in Cell reports (Cambridge) (05.01.2016)
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53. Limiting metastatic breast cancer progression by targeting MK2 stromal signaling
Ramalho-Oliveira, Renata, Faget, Douglas V., Luo, Xianmin, Ye, Jiayu, Stewart, Sheila A.
Published in Journal of bone oncology (01.04.2024)
Published in Journal of bone oncology (01.04.2024)
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Senescent Stromal-Derived Osteopontin Promotes Preneoplastic Cell Growth
PAZOLLI, Ermira, XIANMIN LUO, STEWART, Sheila A, BREHM, Sarah, CARBERY, Kelly, CHUNG, Jun-Jae, PRIOR, Julie L, DOHERTY, Jason, DEMEHRI, Shadmehr, SALAVAGGIONE, Lorena, PIWNICA-WORMS, David
Published in Cancer research (Chicago, Ill.) (01.02.2009)
Published in Cancer research (Chicago, Ill.) (01.02.2009)
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Chemotherapy-induced adipocyte senescence triggers bone loss through RANKL-mediated osteoclastogenesis
Kumar Raut, Ganesh, Yao, Zhangting, Luo, Xianmin, Ren, Qihao, Malachowski, Taylor, Faget, Douglas V., Stewart, Sheila A.
Published in Journal of bone oncology (01.04.2024)
Published in Journal of bone oncology (01.04.2024)
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Osteopontin stimulates preneoplastic cellular proliferation through activation of the MAPK pathway
Luo, Xianmin, Ruhland, Megan K, Pazolli, Ermira, Lind, Anne C, Stewart, Sheila A
Published in Molecular cancer research (01.08.2011)
Published in Molecular cancer research (01.08.2011)
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Targeting stromal p38MAPKalpha triggers innate-adaptive anti-tumor immunity and sensitizes metastatic breast cancer to immunotherapy
Faget, Douglas V., Luo, Xianmin, Inkman, Matthew J., Ren, Qihao, Su, Xinming, Ding, Kai, Waters, Michael R., Kumar Raut, Ganesh, Pandey, Gaurav, Dodhiawala, Paarth B., Ramalho-Oliveira, Renata, Ye, Jiayu, Cole, Thomas, Murali, Bhavna, Zheleznyak, Alexander, Shokeen, Monica, Weiss, Kurt R., Monahan, Joseph B., DeSelm, Carl J., Lee, Adrian V., Oesterreich, Steffi, Weilbaecher, Katherine N., Zhang, Jin, DeNardo, David G., Stewart, Sheila A.
Published in Journal of bone oncology (01.04.2024)
Published in Journal of bone oncology (01.04.2024)
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Hypoglycemia Induces General Neuronal Death, Whereas Hypoxia and Glutamate Transport Blockade Lead to Selective Retinal Ganglion Cell Death In Vitro
Luo, Xianmin, Lambrou, George N, Sahel, Jose A, Hicks, David
Published in Investigative ophthalmology & visual science (01.10.2001)
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Published in Investigative ophthalmology & visual science (01.10.2001)
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Design of novel AlCoFeNiV high-entropy alloys with high-strength and high-ductility
Wang, Xin, An, Zibing, Cai, Jixiang, Jiang, Cheng, Su, Honghong, Luo, Xianmin, Li, Ziyao, Wu, Shichang, Yang, Luyan, Long, Haibo, Zhang, Jianfei, Mao, Shengcheng, Zhang, Ze, Han, Xiaodong
Published in Materials characterization (01.09.2023)
Published in Materials characterization (01.09.2023)
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FHB resistance conferred by Fhb1 is under inhibitory regulation of two genetic loci in wheat (Triticum aestivum L.)
Li, Guoqiang, Yuan, Yang, Zhou, Jiyang, Cheng, Rui, Chen, Ruitong, Luo, Xianmin, Shi, Jinxing, Wang, Heyu, Xu, Boyang, Duan, Youyu, Zhong, Jinkun, Wang, Xin, Kong, Zhongxin, Jia, Haiyan, Ma, Zhengqiang
Published in Theoretical and applied genetics (01.06.2023)
Published in Theoretical and applied genetics (01.06.2023)
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Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss
Murali, Bhavna, Ren, Qihao, Luo, Xianmin, Faget, Douglas V, Wang, Chun, Johnson, Radia Marie, Gruosso, Tina, Flanagan, Kevin C, Fu, Yujie, Leahy, Kathleen, Alspach, Elise, Su, Xinming, Ross, Michael H, Burnette, Barry, Weilbaecher, Katherine N, Park, Morag, Mbalaviele, Gabriel, Monahan, Joseph B, Stewart, Sheila A
Published in Cancer research (Chicago, Ill.) (01.10.2018)
Published in Cancer research (Chicago, Ill.) (01.10.2018)
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Abstract 2962: Chemotherapy induced senescence drives peripheral neuropathy
Malachowski, Taylor, Raut, Ganesh Kumar, Luo, Xianmin, Bagchi, Satarupa Mullick, Stewart, Sheila
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Senescent CAFs mediate immunosuppression and drive breast cancer progression
Ye, Jiayu, Baer, John M, Faget, Douglas V, Morikis, Vasilios A, Ren, Qihao, Melam, Anupama, Delgado, Ana Paula, Luo, Xianmin, Mullick Bagchi, Satarupa, Belle, Jad I, Campos, Edward, Friedman, Michael, Veis, Deborah J, Knudsen, Erik S, Witkiewicz, Agnieszka K, Powers, Scott, Longmore, Gregory D, DeNardo, David G, Stewart, Sheila A
Published in Cancer discovery (01.07.2024)
Published in Cancer discovery (01.07.2024)
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Abstract 2956: Chemotherapy-induced adipocyte senescence triggers bone loss through osteoclast activation
Raut, Ganesh Kumar, Malachowski, Taylor, Holt, Taylor, Oliveira, Renata, Luo, Xianmin, Faget, Douglas, Ren, Qihao, Stewart, Sheila
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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