Synthesis and Evaluation of Novel Inhibitors of Pim-1 and Pim-2 Protein Kinases
Xia, Zuping, Knaak, Christian, Ma, Jian, Beharry, Zanna M, McInnes, Campbell, Wang, Wenxue, Kraft, Andrew S, Smith, Charles D
Published in Journal of medicinal chemistry (08.01.2009)
Published in Journal of medicinal chemistry (08.01.2009)
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Journal Article
Pim protein kinases regulate energy metabolism and cell growth
Beharry, Zanna, Mahajan, Sandeep, Zemskova, Marina, Lin, Ying-Wei, Tholanikunnel, Baby G, Xia, Zuping, Smith, Charles D, Kraft, Andrew S
Published in Proceedings of the National Academy of Sciences - PNAS (11.01.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (11.01.2011)
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Journal Article
A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma
Lin, Ying-Wei, Beharry, Zanna M., Hill, Elizabeth G., Song, Jin H., Wang, Wenxue, Xia, Zuping, Zhang, Zhenhua, Aplan, Peter D., Aster, Jon C., Smith, Charles D., Kraft, Andrew S.
Published in Blood (28.01.2010)
Published in Blood (28.01.2010)
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Journal Article
Discovery and evaluation of inhibitors of human ceramidase
Draper, Jeremiah M, Xia, Zuping, Smith, Ryan A, Zhuang, Yan, Wang, Wenxue, Smith, Charles D
Published in Molecular cancer therapeutics (01.11.2011)
Published in Molecular cancer therapeutics (01.11.2011)
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Identification of the 4‑Position of 3‑Alkynyl and 3‑Heteroaromatic Substituted Pyridine Methanamines as a Key Modification Site Eliciting Increased Potency and Enhanced Selectivity for Cytochrome P‑450 2A6 Inhibition
Denton, Travis T., Srivastava, Pramod, Xia, Zuping, Chen, Gang, Watson, Christy J. W., Wynd, Alec, Lazarus, Philip
Published in Journal of medicinal chemistry (23.08.2018)
Published in Journal of medicinal chemistry (23.08.2018)
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Journal Article
Suppression of Ulcerative Colitis in Mice by Orally Available Inhibitors of Sphingosine Kinase
Maines, Lynn W., Fitzpatrick, Leo R., French, Kevin J., Zhuang, Yan, Xia, Zuping, Keller, Staci N., Upson, John J., Smith, Charles D.
Published in Digestive diseases and sciences (01.04.2008)
Published in Digestive diseases and sciences (01.04.2008)
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Journal Article
Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells
Beharry, Zanna, Zemskova, Marina, Mahajan, Sandeep, Zhang, Fengxue, Ma, Jian, Xia, Zuping, Lilly, Michael, Smith, Charles D, Kraft, Andrew S
Published in Molecular cancer therapeutics (01.06.2009)
Published in Molecular cancer therapeutics (01.06.2009)
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Journal Article
Cellular palmitoylation and trafficking of lipidated peptides
Draper, Jeremiah M., Xia, Zuping, Smith, Charles D.
Published in Journal of lipid research (01.08.2007)
Published in Journal of lipid research (01.08.2007)
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Journal Article
Improved synthesis of a fluorogenic ceramidase substrate
Xia, Zuping, Draper, Jeremiah M., Smith, Charles D.
Published in Bioorganic & medicinal chemistry (01.02.2010)
Published in Bioorganic & medicinal chemistry (01.02.2010)
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Journal Article
Synthesis and Evaluation of Dihydropyrroloquinolines That Selectively Antagonize P-Glycoprotein
Lee, Brian D, Li, Zhanjiang, French, Kevin J, Zhuang, Yan, Xia, Zuping, Smith, Charles D
Published in Journal of medicinal chemistry (11.03.2004)
Published in Journal of medicinal chemistry (11.03.2004)
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Journal Article
Cyclohexyl-octahydro-pyrrolo[1,2-a]pyrazine-Based Inhibitors of Human N-Myristoyltransferase-1
French, Kevin J, Zhuang, Yan, Schrecengost, Randy S, Copper, Jean E, Xia, Zuping, Smith, Charles D
Published in The Journal of pharmacology and experimental therapeutics (01.04.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2004)
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Journal Article
In vitro metabolism of exemestane by hepatic cytochrome P450s: impact of nonsynonymous polymorphisms on formation of the active metabolite 17β‐dihydroexemestane
Peterson, Amity, Xia, Zuping, Chen, Gang, Lazarus, Philip
Published in Pharmacology research & perspectives (01.06.2017)
Published in Pharmacology research & perspectives (01.06.2017)
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Journal Article
Exemestane potency is unchanged by common nonsynonymous polymorphisms in CYP19A1: results of a novel anti‐aromatase activity assay examining exemestane and its derivatives
Peterson, Amity, Xia, Zuping, Chen, Gang, Lazarus, Philip
Published in Pharmacology research & perspectives (01.06.2017)
Published in Pharmacology research & perspectives (01.06.2017)
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Journal Article
Synthesis and Biological Evaluation of Butanoate, Retinoate, and Bis(2,2,2-trichloroethyl)phosphate Derivatives of 5-Fluoro-2′-deoxyuridine and 2′,5-Difluoro-2′-deoxyuridine as Potential Dual Action Anticancer Prodrugs
Xia, Zuping, Wiebe, Leonard I., Miller, Gerald G., Knaus, Edward E.
Published in Archiv der Pharmazie (Weinheim) (01.08.1999)
Published in Archiv der Pharmazie (Weinheim) (01.08.1999)
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Journal Article
Exemestane potency is unchanged by common nonsynonymous polymorphisms in CYP 19A1: results of a novel anti‐aromatase activity assay examining exemestane and its derivatives
Peterson, Amity, Xia, Zuping, Chen, Gang, Lazarus, Philip
Published in Pharmacology research & perspectives (01.06.2017)
Published in Pharmacology research & perspectives (01.06.2017)
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Journal Article