Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome
Asiminas, Antonis, Jackson, Adam D, Louros, Susana R, Till, Sally M, Spano, Teresa, Dando, Owen, Bear, Mark F, Chattarji, Sumantra, Hardingham, Giles E, Osterweil, Emily K, Wyllie, David J A, Wood, Emma R, Kind, Peter C
Published in Science translational medicine (29.05.2019)
Published in Science translational medicine (29.05.2019)
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Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism
Hasel, Philip, Dando, Owen, Jiwaji, Zoeb, Baxter, Paul, Todd, Alison C., Heron, Samuel, Márkus, Nóra M., McQueen, Jamie, Hampton, David W., Torvell, Megan, Tiwari, Sachin S., McKay, Sean, Eraso-Pichot, Abel, Zorzano, Antonio, Masgrau, Roser, Galea, Elena, Chandran, Siddharthan, Wyllie, David J. A., Simpson, T. Ian, Hardingham, Giles E.
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Published in Nature communications (02.05.2017)
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Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
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Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2012)
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Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals
Qiu, Jing, Tan, Yan-Wei, Hagenston, Anna M., Martel, Marc-Andre, Kneisel, Niclas, Skehel, Paul A., Wyllie, David J. A., Bading, Hilmar, Hardingham, Giles E.
Published in Nature communications (18.06.2013)
Published in Nature communications (18.06.2013)
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C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity
Selvaraj, Bhuvaneish T., Livesey, Matthew R., Zhao, Chen, Gregory, Jenna M., James, Owain T., Cleary, Elaine M., Chouhan, Amit K., Gane, Angus B., Perkins, Emma M., Dando, Owen, Lillico, Simon G., Lee, Youn-Bok, Nishimura, Agnes L., Poreci, Urjana, Thankamony, Sai, Pray, Meryll, Vasistha, Navneet A., Magnani, Dario, Borooah, Shyamanga, Burr, Karen, Story, David, McCampbell, Alexander, Shaw, Christopher E., Kind, Peter C., Aitman, Timothy J., Whitelaw, C. Bruce A., Wilmut, Ian, Smith, Colin, Miles, Gareth B., Hardingham, Giles E., Wyllie, David J. A., Chandran, Siddharthan
Published in Nature communications (24.01.2018)
Published in Nature communications (24.01.2018)
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Altered dendritic spine function and integration in a mouse model of fragile X syndrome
Booker, Sam A., Domanski, Aleksander P. F., Dando, Owen R., Jackson, Adam D., Isaac, John T. R., Hardingham, Giles E., Wyllie, David J. A., Kind, Peter C.
Published in Nature communications (23.10.2019)
Published in Nature communications (23.10.2019)
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Physiological normoxia and absence of EGF is required for the long-term propagation of anterior neural precursors from human pluripotent cells
Bilican, Bilada, Livesey, Matthew R, Haghi, Ghazal, Qiu, Jing, Burr, Karen, Siller, Rick, Hardingham, Giles E, Wyllie, David J A, Chandran, Siddharthan
Published in PloS one (17.01.2014)
Published in PloS one (17.01.2014)
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Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction
Perkins, Emma M, Burr, Karen, Banerjee, Poulomi, Mehta, Arpan R, Dando, Owen, Selvaraj, Bhuvaneish T, Suminaite, Daumante, Nanda, Jyoti, Henstridge, Christopher M, Gillingwater, Thomas H, Hardingham, Giles E, Wyllie, David J A, Chandran, Siddharthan, Livesey, Matthew R
Published in Molecular neurodegeneration (04.03.2021)
Published in Molecular neurodegeneration (04.03.2021)
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Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity
Patani, Rickie, Compston, Alastair, Puddifoot, Clare A, Wyllie, David J A, Hardingham, Giles E, Allen, Nicholas D, Chandran, Siddharthan
Published in PloS one (06.10.2009)
Published in PloS one (06.10.2009)
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Genome-wide analysis of the GDSL esterase/lipase family genes in Physcomitrium patens and the involvement of GELP31 in spore germination
Barker, Elizabeth I., Rabbi, Fazle, Brisbourne, Wyllie A., Aparato, Vincent P. M., Escarrega Valenzuela, Vania, Renzaglia, Karen S., Suh, Dae-Yeon
Published in Molecular genetics and genomics : MGG (01.09.2023)
Published in Molecular genetics and genomics : MGG (01.09.2023)
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Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants
Soares da Costa, Tatiana P, Hall, Cody J, Panjikar, Santosh, Wyllie, Jessica A, Christoff, Rebecca M, Bayat, Saadi, Hulett, Mark D, Abbott, Belinda M, Gendall, Anthony R, Perugini, Matthew A
Published in eLife (27.07.2021)
Published in eLife (27.07.2021)
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Accuracy of reporting of family history of colorectal cancer
Mitchell, R J, Brewster, D, Campbell, H, Porteous, M E M, Wyllie, A H, Bird, C C, Dunlop, M G
Published in Gut (01.02.2004)
Published in Gut (01.02.2004)
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Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder
Simões de Oliveira, Laura, O'Leary, Heather E, Nawaz, Sarfaraz, Loureiro, Rita, Davenport, Elizabeth C, Baxter, Paul, Louros, Susana R, Dando, Owen, Perkins, Emma, Peltier, Julien, Trost, Matthias, Osterweil, Emily K, Hardingham, Giles E, Cousin, Michael A, Chattarji, Sumantra, Booker, Sam A, Benke, Tim A, Wyllie, David J A, Kind, Peter C
Published in Molecular autism (14.06.2024)
Published in Molecular autism (14.06.2024)
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Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1
McQueen, Jamie, Ryan, Tomás J, McKay, Sean, Marwick, Katie, Baxter, Paul, Carpanini, Sarah M, Wishart, Thomas M, Gillingwater, Thomas H, Manson, Jean C, Wyllie, David J A, Grant, Seth G N, McColl, Barry W, Komiyama, Noboru H, Hardingham, Giles E
Published in eLife (21.07.2017)
Published in eLife (21.07.2017)
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