Convection-Enhanced Delivery of Carboplatin PLGA Nanoparticles for the Treatment of Glioblastoma
Arshad, Azeem, Yang, Bin, Bienemann, Alison S, Barua, Neil U, Wyatt, Marcella J, Woolley, Max, Johnson, Dave E, Edler, Karen J, Gill, Steven S
Published in PloS one (17.07.2015)
Published in PloS one (17.07.2015)
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Repurposing the anti-epileptic drug sodium valproate as an adjuvant treatment for diffuse intrinsic pontine glioma
Killick-Cole, Clare L, Singleton, William G B, Bienemann, Alison S, Asby, Daniel J, Wyatt, Marcella J, Boulter, Lisa J, Barua, Neil U, Gill, Steven S
Published in PloS one (25.05.2017)
Published in PloS one (25.05.2017)
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PEGylation improves the receptor-mediated transfection efficiency of peptide-targeted, self-assembling, anionic nanocomplexes
Tagalakis, Aristides D., Kenny, Gavin D., Bienemann, Alison S., McCarthy, David, Munye, Mustafa M., Taylor, Hannah, Wyatt, Marcella J., Lythgoe, Mark F., White, Edward A., Hart, Stephen L.
Published in Journal of controlled release (28.01.2014)
Published in Journal of controlled release (28.01.2014)
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The distribution, clearance, and brainstem toxicity of panobinostat administered by convection-enhanced delivery
Singleton, William G B, Bienemann, Alison S, Woolley, Max, Johnson, David, Lewis, Owen, Wyatt, Marcella J, Damment, Stephen J P, Boulter, Lisa J, Killick-Cole, Clare L, Asby, Daniel J, Gill, Steven S
Published in Journal of neurosurgery. Pediatrics (01.09.2018)
Published in Journal of neurosurgery. Pediatrics (01.09.2018)
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Combined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity
Asby, Daniel J, Killick-Cole, Clare L, Boulter, Lisa J, Singleton, William Gb, Asby, Claire A, Wyatt, Marcella J, Barua, Neil U, Bienemann, Alison S, Gill, Steven S
Published in Cancer management and research (01.01.2018)
Published in Cancer management and research (01.01.2018)
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A novel implantable catheter system with transcutaneous port for intermittent convection-enhanced delivery of carboplatin for recurrent glioblastoma
Barua, Neil U., Hopkins, Kirsten, Woolley, Max, O'Sullivan, Stephen, Harrison, Rob, Edwards, Richard J., Bienemann, Alison S., Wyatt, Marcella J., Arshad, Azeem, Gill, Steven S.
Published in Drug delivery (02.01.2016)
Published in Drug delivery (02.01.2016)
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Intrastriatal convection-enhanced delivery results in widespread perivascular distribution in a pre-clinical model
Barua, Neil U, Bienemann, Alison S, Hesketh, Shirley, Wyatt, Marcella J, Castrique, Emma, Love, Seth, Gill, Steven S
Published in Fluids and barriers of the CNS (20.01.2012)
Published in Fluids and barriers of the CNS (20.01.2012)
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Clearance and toxicity of recombinant methionyl human glial cell line-derived neurotrophic factor (r-metHu GDNF) following acute convection-enhanced delivery into the striatum
Taylor, Hannah, Barua, Neil, Bienemann, Alison, Wyatt, Marcella, Castrique, Emma, Foster, Rebecca, Luz, Matthias, Fibiger, Christian, Mohr, Erich, Gill, Steven
Published in PloS one (20.03.2013)
Published in PloS one (20.03.2013)
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Convection-enhanced delivery of neprilysin: a novel amyloid-β-degrading therapeutic strategy
Barua, Neil U, Miners, J Scott, Bienemann, Alison S, Wyatt, Marcella J, Welser, Katharina, Tabor, Alethea B, Hailes, Helen C, Love, Seth, Gill, Steven S
Published in Journal of Alzheimer's disease (01.01.2012)
Published in Journal of Alzheimer's disease (01.01.2012)
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Reduction of early vein graft thrombosis by tissue plasminogen activator gene transfer
Thomas, Anita C, Wyatt, Marcella J, Newby, Andrew C
Published in Thrombosis and haemostasis (01.07.2009)
Published in Thrombosis and haemostasis (01.07.2009)
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An evaluation of the relationships between catheter design and tissue mechanics in achieving high-flow convection-enhanced delivery
White, Edward, Bienemann, Alison, Malone, John, Megraw, Lisa, Bunnun, Chotirote, Wyatt, Marcella, Gill, Steven
Published in Journal of neuroscience methods (15.07.2011)
Published in Journal of neuroscience methods (15.07.2011)
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TRTH-18. COMBINED TOPOTECAN AND CARBOPLATIN THERAPY FOR DIPG SUPPRESSES CELL GROWTH IN VITRO AND IS WELL TOLERATED WHEN DELIVERED BY CONVECTION ENHANCED DELIVERY IN VIVO
Bienemann, Alison, Killick-Cole, Clare, Singleton, William, Arshad, Azeem, Marcella, Wyatt, Neil, Barua, Steven, Gill
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
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Preclinical analysis of sodium valproate for the treatment of pediatric diffuse intrinsic pontine glioma and adult glioblastoma
Killick-Cole, Clare, Bienemann, Ali, Singleton, Will, Wyatt, Marcella, Asby, Daniel, Boulter, Lisa, Haynes, Harry, Barua, Neil, Gill, Steven
Published in Neuro-oncology (Charlottesville, Va.) (31.01.2018)
Published in Neuro-oncology (Charlottesville, Va.) (31.01.2018)
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Convection enhanced delivery of tri-block copolymer nano-micelles: a method of direct intraparenchymal water-insoluble drug delivery for the treatment of high-grade glioma
Singleton, Will, Collins, Andy, Bienemann, Ali, Killick-Cole, Clare, Asby, Daniel, Haynes, Harry, Wyatt, Marcella, Boulter, Lisa, Gill, Steven
Published in Neuro-oncology (Charlottesville, Va.) (31.01.2018)
Published in Neuro-oncology (Charlottesville, Va.) (31.01.2018)
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An evaluation of the safety and feasibility of convection-enhanced delivery of carboplatin into the white matter as a potential treatment for high-grade glioma
White, Edward, Bienemann, Alison, Pugh, John, Castrique, Emma, Wyatt, Marcella, Taylor, Hannah, Cox, Alan, Mcleod, Cameron, Gill, Steven
Published in Journal of neuro-oncology (01.05.2012)
Published in Journal of neuro-oncology (01.05.2012)
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TRTH-19. PRECLINICAL ANALYSIS OF SODIUM VALPROATE FOR THE TREATMENT OF DIPG BY CONVECTION ENHANCED DELIVERY
Killick-Cole, Clare, Bienemann, Ali, Asby, Daniel, Singleton, William, Wyatt, Marcella, Boulter, Lisa, Barua, Neil, Gill, Steven
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
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PDTM-14. THE DISTRIBUTION, CLEARANCE AND TOXICITY OF PANOBINOSTAT ADMINISTERED TO JUVENILE RAT AND PIG BRAINSTEM BY CONVECTION ENHANCED DELIVERY
Singleton, Will, Bienemann, Alison, Woolley, Max, Johnson, David, Lewis, Owen, Wyatt, Marcella, Damment, Steve, Boulter, Lisa, Killick-Cole, Clare, Asby, Daniel, Gill, Steven
Published in Neuro-oncology (Charlottesville, Va.) (06.11.2017)
Published in Neuro-oncology (Charlottesville, Va.) (06.11.2017)
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HG-84SODIUM VALPROATE POTENTIATES CARBOPLATIN INDUCED CYTOTOXICITY SUPPORTING ITS USE AS AN ADJUVANT CHEMOTHERAPEUTIC FOR THE TREATMENT OF DIPG
Killick-Cole, Clare, Bienemann, Alison, Wyatt, Marcella, Boulter, Lisa, Asby, Daniel, Singleton, William, Barua, Neil, Gill, Steven
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2016)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2016)
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On the biology of saphenous vein grafts fitted with external synthetic sheaths and stents
Jeremy, Jamie Y, Gadsdon, Pat, Shukla, Nilima, Vijayan, Vikram, Wyatt, Marcella, Newby, Andrew C, Angelini, Gianni D
Published in Biomaterials (01.02.2007)
Published in Biomaterials (01.02.2007)
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Distribution properties of lentiviral vectors administered into the striatum by convection-enhanced delivery
White, Edward, Bienemann, Alison, Megraw, Lisa, Bunnun, Chotirote, Wyatt, Marcella, Taylor, Hannah, Gill, Steven
Published in Human gene therapy (01.01.2012)
Published in Human gene therapy (01.01.2012)
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