Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients
Gros, Alena, Parkhurst, Maria R, Tran, Eric, Pasetto, Anna, Robbins, Paul F, Ilyas, Sadia, Prickett, Todd D, Gartner, Jared J, Crystal, Jessica S, Roberts, Ilana M, Trebska-McGowan, Kasia, Wunderlich, John R, Yang, James C, Rosenberg, Steven A
Published in Nature medicine (01.04.2016)
Published in Nature medicine (01.04.2016)
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Immunogenicity of somatic mutations in human gastrointestinal cancers
Tran, Eric, Ahmadzadeh, Mojgan, Lu, Yong-Chen, Gros, Alena, Turcotte, Simon, Robbins, Paul F., Gartner, Jared J., Zheng, Zhili, Li, Yong F., Ray, Satyajit, Wunderlich, John R., Somerville, Robert P., Rosenberg, Steven A.
Published in Science (American Association for the Advancement of Science) (11.12.2015)
Published in Science (American Association for the Advancement of Science) (11.12.2015)
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PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors
Gros, Alena, Robbins, Paul F, Yao, Xin, Li, Yong F, Turcotte, Simon, Tran, Eric, Wunderlich, John R, Mixon, Arnold, Farid, Shawn, Dudley, Mark E, Hanada, Ken-Ichi, Almeida, Jorge R, Darko, Sam, Douek, Daniel C, Yang, James C, Rosenberg, Steven A
Published in The Journal of clinical investigation (01.05.2014)
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Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer
Tran, Eric, Turcotte, Simon, Gros, Alena, Robbins, Paul F., Lu, Yong-Chen, Dudley, Mark E., Wunderlich, John R., Somerville, Robert P., Hogan, Katherine, Hinrichs, Christian S., Parkhurst, Maria R., Yang, James C., Rosenberg, Steven A.
Published in Science (American Association for the Advancement of Science) (09.05.2014)
Published in Science (American Association for the Advancement of Science) (09.05.2014)
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A Phase II Study of Tumor-infiltrating Lymphocyte Therapy for Human Papillomavirus-associated Epithelial Cancers
Stevanović, Sanja, Helman, Sarah R, Wunderlich, John R, Langhan, Michelle M, Doran, Stacey L, Kwong, Mei Li M, Somerville, Robert P T, Klebanoff, Christopher A, Kammula, Udai S, Sherry, Richard M, Yang, James C, Rosenberg, Steven A, Hinrichs, Christian S
Published in Clinical cancer research (01.03.2019)
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Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4
Lin, Jimmy C, Wunderlich, John R, Prickett, Todd D, Yates, Kristin E, Cruz, Pedro, Agrawal, Neena S, Cronin, Julia C, Samuels, Yardena, Wei, Xiaomu, Rosenberg, Steven A
Published in Nature genetics (01.10.2009)
Published in Nature genetics (01.10.2009)
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Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: a single-centre, two-stage, single-arm, phase 2 study
Chandran, Smita S, PhD, Somerville, Robert P T, PhD, Yang, James C, MD, Sherry, Richard M, MD, Klebanoff, Christopher A, MD, Goff, Stephanie L, MD, Wunderlich, John R, MD, Danforth, David N, MD, Zlott, Daniel, PharmD, Paria, Biman C, PhD, Sabesan, Arvind C, MD, Srivastava, Abhishek K, PhD, Xi, Liqiang, PhD, Pham, Trinh H, MS, Raffeld, Mark, MD, White, Donald E, MS, Toomey, Mary Ann, BSN, Rosenberg, Steven A, MD, Kammula, Udai S, Dr
Published in The lancet oncology (01.06.2017)
Published in The lancet oncology (01.06.2017)
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Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
Ahmadzadeh, Mojgan, Johnson, Laura A., Heemskerk, Bianca, Wunderlich, John R., Dudley, Mark E., White, Donald E., Rosenberg, Steven A.
Published in Blood (20.08.2009)
Published in Blood (20.08.2009)
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Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells
Stevanović, Sanja, Draper, Lindsey M, Langhan, Michelle M, Campbell, Tracy E, Kwong, Mei Li, Wunderlich, John R, Dudley, Mark E, Yang, James C, Sherry, Richard M, Kammula, Udai S, Restifo, Nicholas P, Rosenberg, Steven A, Hinrichs, Christian S
Published in Journal of clinical oncology (10.05.2015)
Published in Journal of clinical oncology (10.05.2015)
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Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1
ROBBINS, Paul F, MORGAN, Richard A, KAMMULA, Udai S, HUGHES, Marybeth S, RESTIFO, Nicholas P, RAFFELD, Mark, LEE, Chyi-Chia Richard, LEVY, Catherine L, LI, Yong F, EL-GAMIL, Mona, SCHWARZ, Susan L, LAURENCOT, Carolyn, FELDMAN, Steven A, ROSENBERG, Steven A, YANG, James C, SHERRY, Richard M, DUDLEY, Mark E, WUNDERLICH, John R, NAHVI, Azam V, HELMAN, Lee J, MACKALL, Crystal L
Published in Journal of clinical oncology (01.03.2011)
Published in Journal of clinical oncology (01.03.2011)
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CD8+ Enriched Young Tumor Infiltrating Lymphocytes Can Mediate Regression of Metastatic Melanoma
DUDLEY, Mark E, GROSS, Colin A, RESTIFO, Nicholas P, WUNDERLICH, John R, PRIETO, Peter A, HONG, Jenny J, LANGAN, Russell C, ZLOTT, Daniel A, MORTON, Kathleen E, WHITE, Donald E, LAURENCOT, Carolyn M, ROSENBERG, Steven A, LANGHAN, Michelle M, GARCIA, Marcos R, SHERRY, Richard M, YANG, James C, PHAN, Giao Q, KAMMULA, Udai S, HUGHES, Marybeth S, CITRIN, Deborah E
Published in Clinical cancer research (15.12.2010)
Published in Clinical cancer research (15.12.2010)
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Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers
Parkhurst, Maria R, Robbins, Paul F, Tran, Eric, Prickett, Todd D, Gartner, Jared J, Jia, Li, Ivey, Gabriel, Li, Yong F, El-Gamil, Mona, Lalani, Almin, Crystal, Jessica S, Sachs, Abraham, Groh, Eric, Ray, Satyajit, Ngo, Lien T, Kivitz, Scott, Pasetto, Anna, Yossef, Rami, Lowery, Frank J, Goff, Stephanie L, Lo, Winifred, Cafri, Gal, Deniger, Drew C, Malekzadeh, Parisa, Ahmadzadeh, Mojgan, Wunderlich, John R, Somerville, Robert P T, Rosenberg, Steven A
Published in Cancer discovery (01.08.2019)
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A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response
Robbins, Paul F, Kassim, Sadik H, Tran, Thai L N, Crystal, Jessica S, Morgan, Richard A, Feldman, Steven A, Yang, James C, Dudley, Mark E, Wunderlich, John R, Sherry, Richard M, Kammula, Udai S, Hughes, Marybeth S, Restifo, Nicholas P, Raffeld, Mark, Lee, Chyi-Chia R, Li, Yong F, El-Gamil, Mona, Rosenberg, Steven A
Published in Clinical cancer research (01.03.2015)
Published in Clinical cancer research (01.03.2015)
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Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy
ROSENBERG, Steven A, YANG, James C, MORTON, Kathleen E, LAURENCOT, Carolyn M, STEINBERG, Seth M, WHITE, Donald E, DUDLEY, Mark E, SHERRY, Richard M, KAMMULA, Udai S, HUGHES, Marybeth S, PHAN, Giao Q, CITRIN, Deborah E, RESTIFO, Nicholas P, ROBBINS, Paul F, WUNDERLICH, John R
Published in Clinical cancer research (01.07.2011)
Published in Clinical cancer research (01.07.2011)
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Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma
Goff, Stephanie L, Dudley, Mark E, Citrin, Deborah E, Somerville, Robert P, Wunderlich, John R, Danforth, David N, Zlott, Daniel A, Yang, James C, Sherry, Richard M, Kammula, Udai S, Klebanoff, Christopher A, Hughes, Marybeth S, Restifo, Nicholas P, Langhan, Michelle M, Shelton, Thomas E, Lu, Lily, Kwong, Mei Li M, Ilyas, Sadia, Klemen, Nicholas D, Payabyab, Eden C, Morton, Kathleen E, Toomey, Mary Ann, Steinberg, Seth M, White, Donald E, Rosenberg, Steven A
Published in Journal of clinical oncology (10.07.2016)
Published in Journal of clinical oncology (10.07.2016)
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T-cell Responses to TP53 "Hotspot" Mutations and Unique Neoantigens Expressed by Human Ovarian Cancers
Deniger, Drew C, Pasetto, Anna, Robbins, Paul F, Gartner, Jared J, Prickett, Todd D, Paria, Biman C, Malekzadeh, Parisa, Jia, Li, Yossef, Rami, Langhan, Michelle M, Wunderlich, John R, Danforth, David N, Somerville, Robert P T, Rosenberg, Steven A
Published in Clinical cancer research (15.11.2018)
Published in Clinical cancer research (15.11.2018)
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Randomized Selection Design Trial Evaluating CD8+-Enriched Versus Unselected Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy for Patients With Melanoma
DUDLEY, Mark E, GROSS, Colin A, WUNDERLICH, John R, KAMMULA, Udai S, SHERRY, Richard M, YANG, James C, PHAN, Giao Q, HUGHES, Marybeth S, LAURENCOT, Carolyn M, ROSENBERG, Steven A, SOMERVILLE, Robert P. T, HONG, Young, SCHAUB, Nicholas P, ROSATI, Shannon F, WHITE, Donald E, NATHAN, Debbie, RESTIFO, Nicholas P, STEINBERG, Seth M
Published in Journal of clinical oncology (10.06.2013)
Published in Journal of clinical oncology (10.06.2013)
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Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes
Morgan, Richard A, Dudley, Mark E, Wunderlich, John R, Hughes, Marybeth S, Yang, James C, Sherry, Richard M, Royal, Richard E, Topalian, Suzanne L, Kammula, Udai S, Restifo, Nicholas P, Zheng, Zhili, Nahvi, Azam, de Vries, Christiaan R, Rogers-Freezer, Linda J, Mavroukakis, Sharon A, Rosenberg, Steven A
Published in Science (American Association for the Advancement of Science) (06.10.2006)
Published in Science (American Association for the Advancement of Science) (06.10.2006)
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A Phase I Study on Adoptive Immunotherapy Using Gene-Modified T Cells for Ovarian Cancer
KERSHAW, Michael H, WESTWARD, Jennifer A, CHEN, Clara C, YANG, James C, ROSENBERG, Steven A, HWU, Patrick, PARKER, Linda L, GANG WANG, ESHHAR, Zelig, MAVROUKAKIS, Sharon A, WHITE, Donald E, WUNDERLICH, John R, CANEVARI, Silvana, ROGERS-FREEZER, Linda
Published in Clinical cancer research (15.10.2006)
Published in Clinical cancer research (15.10.2006)
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Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
Johnson, Laura A., Morgan, Richard A., Dudley, Mark E., Cassard, Lydie, Yang, James C., Hughes, Marybeth S., Kammula, Udai S., Royal, Richard E., Sherry, Richard M., Wunderlich, John R., Lee, Chyi-Chia R., Restifo, Nicholas P., Schwarz, Susan L., Cogdill, Alexandria P., Bishop, Rachel J., Kim, Hung, Brewer, Carmen C., Rudy, Susan F., VanWaes, Carter, Davis, Jeremy L., Mathur, Aarti, Ripley, Robert T., Nathan, Debbie A., Laurencot, Carolyn M., Rosenberg, Steven A.
Published in Blood (16.07.2009)
Published in Blood (16.07.2009)
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