Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance
Turpin, Sarah M., Nicholls, Hayley T., Willmes, Diana M., Mourier, Arnaud, Brodesser, Susanne, Wunderlich, Claudia M., Mauer, Jan, Xu, Elaine, Hammerschmidt, Philipp, Brönneke, Hella S., Trifunovic, Aleksandra, LoSasso, Giuseppe, Wunderlich, F. Thomas, Kornfeld, Jan-Wilhelm, Blüher, Matthias, Krönke, Martin, Brüning, Jens C.
Published in Cell metabolism (07.10.2014)
Published in Cell metabolism (07.10.2014)
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Journal Article
Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment
Wunderlich, Claudia M., Ackermann, P. Justus, Ostermann, Anna Lena, Adams-Quack, Petra, Vogt, Merly C., Tran, My-Ly, Nikolajev, Alexei, Waisman, Ari, Garbers, Christoph, Theurich, Sebastian, Mauer, Jan, Hövelmeyer, Nadine, Wunderlich, F. Thomas
Published in Nature communications (25.04.2018)
Published in Nature communications (25.04.2018)
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Journal Article
Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance
Tsaousidou, Eva, Paeger, Lars, Belgardt, Bengt F., Pal, Martin, Wunderlich, Claudia M., Brönneke, Hella, Collienne, Ursel, Hampel, Brigitte, Wunderlich, F. Thomas, Schmidt-Supprian, Marc, Kloppenburg, Peter, Brüning, Jens C.
Published in Cell reports (Cambridge) (20.11.2014)
Published in Cell reports (Cambridge) (20.11.2014)
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Journal Article
Mosaic Deficiency in Mitochondrial Oxidative Metabolism Promotes Cardiac Arrhythmia during Aging
Baris, Olivier R., Ederer, Stefan, Neuhaus, Johannes F.G., von Kleist-Retzow, Jürgen-Christoph, Wunderlich, Claudia M., Pal, Martin, Wunderlich, F. Thomas, Peeva, Viktoriya, Zsurka, Gabor, Kunz, Wolfram S., Hickethier, Tilman, Bunck, Alexander C., Stöckigt, Florian, Schrickel, Jan W., Wiesner, Rudolf J.
Published in Cell metabolism (05.05.2015)
Published in Cell metabolism (05.05.2015)
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Journal Article
Diet-Induced Growth Is Regulated via Acquired Leptin Resistance and Engages a Pomc-Somatostatin-Growth Hormone Circuit
Löhr, Heiko, Hess, Simon, Pereira, Mafalda M.A., Reinoß, Philip, Leibold, Sandra, Schenkel, Christel, Wunderlich, Claudia M., Kloppenburg, Peter, Brüning, Jens C., Hammerschmidt, Matthias
Published in Cell reports (Cambridge) (08.05.2018)
Published in Cell reports (Cambridge) (08.05.2018)
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Journal Article
Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice
Pal, Martin, Wunderlich, Claudia M, Spohn, Gabriele, Brönneke, Hella S, Schmidt-Supprian, Marc, Wunderlich, F Thomas
Published in PloS one (17.01.2013)
Published in PloS one (17.01.2013)
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Journal Article
Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma
Mittenbühler, Melanie J., Sprenger, Hans-Georg, Gruber, Sabine, Wunderlich, Claudia M., Kern, Lara, Brüning, Jens C., Wunderlich, F. Thomas
Published in Molecular metabolism (Germany) (01.11.2018)
Published in Molecular metabolism (Germany) (01.11.2018)
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Journal Article
Cutting edge: Inhibition of IL-6 trans-signaling protects from malaria-induced lethality in mice
Wunderlich, Claudia M, Delić, Denis, Behnke, Kristina, Meryk, Andreas, Ströhle, Peter, Chaurasia, Bhagirath, Al-Quraishy, Saleh, Wunderlich, Frank, Brüning, Jens C, Wunderlich, F Thomas
Published in The Journal of immunology (1950) (01.05.2012)
Published in The Journal of immunology (1950) (01.05.2012)
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Journal Article
Obesity Promotes Liver Carcinogenesis via Mcl-1 Stabilization Independent of IL-6Rα Signaling
Gruber, Sabine, Straub, Beate K., Ackermann, P. Justus, Wunderlich, Claudia M., Mauer, Jan, Seeger, Jens M., Büning, Hildegard, Heukamp, Lukas, Kashkar, Hamid, Schirmacher, Peter, Brüning, Jens C., Wunderlich, F. Thomas
Published in Cell reports (Cambridge) (29.08.2013)
Published in Cell reports (Cambridge) (29.08.2013)
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Journal Article
Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting
Biglari, Nasim, Gaziano, Isabella, Schumacher, Jonas, Radermacher, Jan, Paeger, Lars, Klemm, Paul, Chen, Weiyi, Corneliussen, Svenja, Wunderlich, Claudia M., Sue, Michael, Vollmar, Stefan, Klöckener, Tim, Sotelo-Hitschfeld, Tamara, Abbasloo, Amin, Edenhofer, Frank, Reimann, Frank, Gribble, Fiona M., Fenselau, Henning, Kloppenburg, Peter, Wunderlich, Frank T., Brüning, Jens C.
Published in Nature neuroscience (01.07.2021)
Published in Nature neuroscience (01.07.2021)
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Journal Article
Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver
Henschke, Sinika, Nolte, Hendrik, Magoley, Judith, Kleele, Tatjana, Brandt, Claus, Hausen, A Christine, Wunderlich, Claudia M, Bauder, Corinna A, Aschauer, Philipp, Manley, Suliana, Langer, Thomas, Wunderlich, F Thomas, Brüning, Jens C
Published in Science (American Association for the Advancement of Science) (26.04.2024)
Published in Science (American Association for the Advancement of Science) (26.04.2024)
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Journal Article
Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity
Ernst, Marianne B, Wunderlich, Claudia M, Hess, Simon, Paehler, Moritz, Mesaros, Andrea, Koralov, Sergei B, Kleinridders, André, Husch, Andreas, Münzberg, Heike, Hampel, Brigitte, Alber, Jens, Kloppenburg, Peter, Brüning, Jens C, Wunderlich, F Thomas
Published in The Journal of neuroscience (16.09.2009)
Published in The Journal of neuroscience (16.09.2009)
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Journal Article
Enhanced Stat3 Activation in POMC Neurons Provokes Negative Feedback Inhibition of Leptin and InsulinSignaling in Obesity
Ernst, Marianne B, Wunderlich, Claudia M, Hess, Simon, Paehler, Moritz, Mesaros, Andrea, Koralov, Sergei B, Kleinridders, Andre, Husch, Andreas, Munzberg, Heike, Hampel, Brigitte, Alber, Jens, Kloppenburg, Peter, Bruning, Jens C, Wunderlich, F. Thomas
Published in The Journal of neuroscience (16.09.2009)
Published in The Journal of neuroscience (16.09.2009)
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Journal Article
Mechanisms of chronic JAK-STAT3-SOCS3 signaling in obesity
Wunderlich, Claudia M., Hövelmeyer, Nadine, Wunderlich, F. Thomas
Published in JAK-STAT (01.04.2013)
Published in JAK-STAT (01.04.2013)
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Journal Article
BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella
Andree, Maria, Seeger, Jens M, Schüll, Stephan, Coutelle, Oliver, Wagner-Stippich, Diana, Wiegmann, Katja, Wunderlich, Claudia M, Brinkmann, Kerstin, Broxtermann, Pia, Witt, Axel, Fritsch, Melanie, Martinelli, Paola, Bielig, Harald, Lamkemeyer, Tobias, Rugarli, Elena I, Kaufmann, Thomas, Sterner-Kock, Anja, Wunderlich, F Thomas, Villunger, Andreas, Martins, L Miguel, Krönke, Martin, Kufer, Thomas A, Utermöhlen, Olaf, Kashkar, Hamid
Published in The EMBO journal (01.10.2014)
Published in The EMBO journal (01.10.2014)
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Journal Article
Single and Transient Ca2+ Peaks in Podocytes do not induce Changes in Glomerular Filtration and Perfusion
Koehler, Sybille, Brähler, Sebastian, Kuczkowski, Alexander, Binz, Julia, Hackl, Matthias J., Hagmann, Henning, Höhne, Martin, Vogt, Merly C., Wunderlich, Claudia M., Wunderlich, F. Thomas, Schweda, Frank, Schermer, Bernhard, Benzing, Thomas, Brinkkoetter, Paul T.
Published in Scientific reports (19.10.2016)
Published in Scientific reports (19.10.2016)
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Journal Article
Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity
Geibel, Mirjam, Badurek, Sylvia, Horn, Jacqueline M., Vatanashevanopakorn, Chinnavuth, Koudelka, Juraj, Wunderlich, Claudia M., Brönneke, Hella S., Wunderlich, F. Thomas, Minichiello, Liliana
Published in Nature communications (12.03.2014)
Published in Nature communications (12.03.2014)
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Journal Article
Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling
Rastetter, Raphael H, Blömacher, Margit, Drebber, Uta, Marko, Marija, Behrens, Juliane, Solga, Roxana, Hojeili, Sarah, Bhattacharya, Kurchi, Wunderlich, Claudia M, Wunderlich, F Thomas, Odenthal, Margarete, Ziemann, Anja, Eichinger, Ludwig, Clemen, Christoph S
Published in BMC cancer (15.09.2015)
Published in BMC cancer (15.09.2015)
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Journal Article
Single and Transient Ca 2+ Peaks in Podocytes do not induce Changes in Glomerular Filtration and Perfusion
Koehler, Sybille, Brähler, Sebastian, Kuczkowski, Alexander, Binz, Julia, Hackl, Matthias J, Hagmann, Henning, Höhne, Martin, Vogt, Merly C, Wunderlich, Claudia M, Wunderlich, F Thomas, Schweda, Frank, Schermer, Bernhard, Benzing, Thomas, Brinkkoetter, Paul T
Published in Scientific reports (19.10.2016)
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Published in Scientific reports (19.10.2016)
Journal Article